Ling Wang

US Patent:

7446671, Nov 4, 2008

Filed:

Dec 11, 2003

Appl. No.:

10/539983

Inventors:

Demetri Giannopoulos - Norwalk CT, US
Ling Wang - Millwood NY, US

Assignee:

Koninklijke Philips Electronics N.V. - Eindhoven

International Classification:

G08B 1/08

US Classification:

34082572, 398106

Abstract:

A method for associating a group of lighting units in a wireless-controlled lighting system to respective buttons or other control elements on a remote control. Each of the lighting units transmits, via modulation of its own illumination light, a unique identification code for the respective unit. The remote control is successively positioned to receive the modulated light from each lighting unit and, at each position, the user activates a respective control element of the remote control for association with the lighting unit. The remote control then transmits to a control master for the group the unique codes and codes identifying the respective control elements with which they have been associated.

US Patent:

8476458, Jul 2, 2013

Filed:

Jun 19, 2008

Appl. No.:

12/665751

Inventors:

Ronen Marmorstein - Swarthmore PA, US
Xin Liu - Menlo Park CA, US
Philip A. Cole - Baltimore MD, US
Ling Wang - Seattle WA, US
Erin M. Bowers - Baltimore MD, US
David J. Meyers - Towson MD, US
Chandrani Mukherjee - Baltimore MD, US

Assignee:

The Wistar Institute - Philadelphia PA
The John Hopkins University - Baltimore MD

International Classification:

C07D 231/00
C07D 231/06
C07D 307/00
C07D 317/00
C07D 323/02

US Classification:

5483657, 5483561, 5483661, 5483791, 549429

Abstract:

The present invention relates to a method for identifying compounds that modulate the activity of p300/CBP. Compounds of the invention are identified by designing or screening for a compound which binds to at least one amino acid residue of the newly identified lysine-CoA inhibitor binding site, L1 loop, electronegative pocket, or electronegative groove of the HAT domain of p300/CBP and testing the compound for its ability to modulate the activity of p300/CBP. Compositions and methods for preventing or treating diseases or disorders associated with p300/CBP are also provided as is a method for producing a semi-synthetic HAT domain.

US Patent:

20130345267, Dec 26, 2013

Filed:

May 30, 2013

Appl. No.:

13/905222

Inventors:

Philip A. Cole - Baltimore MD, US
Ling Wang - Seattle WA, US
Erin M. Bowers - Baltimore MD, US
David J. Meyers - Towson MD, US
Chandrani Mukherjee - Baltimore MD, US

International Classification:

C07D 405/06

US Classification:

514369, 435184, 514404, 514375, 435 74, 506 8, 5483657, 506 9, 548183, 548224

Abstract:

The present invention relates to a method for identifying compounds that modulate the activity of p300/CBP. Compounds of the invention are identified by designing or screening for a compound which binds to at least one amino acid residue of the newly identified lysine-CoA inhibitor binding site, L1 loop, electronegative pocket, or electronegative groove of the HAT domain of p300/CBP and testing the compound for its ability to modulate the activity of p300/CBP. Compositions and methods for preventing or treating diseases or disorders associated with p300/CBP are also provided as is a method for producing a semi-synthetic HAT domain.