Lisa T Kajisa from 769 Oregon Ave, Palo Alto, CA 94303, age 61, Phone: (408)5541371

Methods For Improved Array Preparation
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US Patent:

6800439, Oct 5, 2004
Filed:

Feb 7, 2001
Appl. No.:

09/779389
Inventors:

Glenn McGall - Mountain View CA
Lisa Kajisa - San Jose CA
Mark Trulson - San Jose CA
Assignee:

Affymetrix, Inc. - Santa Clara CA
International Classification:

G01N 3358
US Classification:

435 6, 435 71, 436518, 436524, 436527, 536 253
Abstract:

Improved nucleic acid arrays are provided which have been prepared in a non-oxidizing atmosphere.

Methods Of Enhancing Functional Performance Of Nucleic Acid Arrays
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US Patent:

6806361, Oct 19, 2004
Filed:

Mar 15, 2001
Appl. No.:

09/811143
Inventors:

Lisa Kajisa - San Jose CA
Glenn McGall - Mountain View CA
Mark Trulson - San Jose CA
Assignee:

Affymetrix, Inc. - Santa Clara CA
International Classification:

C07H 2100
US Classification:

536 253, 536 221, 536 231, 536 243, 435 8
Abstract:

Methods are provided for preparing nucleic acid arrays on a support. In these methods a plurality of nucleic acids are synthesized on the support and the synthesis steps are followed by drying steps in which the array is exposed to a dry atmosphere following the synthesis steps.

Phosphite Ester Oxidation In Nucleic Acid Array Preparation
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US Patent:

6833450, Dec 21, 2004
Filed:

Mar 15, 2001
Appl. No.:

09/810434
Inventors:

Glenn McGall - Mountain View CA
Lisa Kajisa - San Jose CA
Assignee:

Affymetrix, Inc. - Santa Clara CA
International Classification:

C07H 2100
US Classification:

536 253, 436809, 536 2531, 536 2532
Abstract:

Methods are provided for preparing nucleic acid arrays on a support. In these methods a plurality of nucleic acids are synthesized on the support and the synthesis steps include oxidizing a phosphite triester nucleic acid linkage to a phosphate triester nucleic acid linkage using a solution about 0. 005 to about 0. 05 M iodine in a mixture comprising water and organic solvent.

Methods For Array Preparation Using Substrate Rotation
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US Patent:

7005259, Feb 28, 2006
Filed:

Jun 1, 2001
Appl. No.:

09/871610
Inventors:

Glenn McGall - Mountain View CA, US
Lisa Kajisa - San Jose CA, US
Bradley A Kreger - Elk Grove CA, US
Assignee:

Affymetrix, Inc. - Santa Clara CA
International Classification:

C12Q 1/68
C12M 1/36
G01N 15/06
C07H 21/04
US Classification:

435 6, 435174, 4352831, 4352867, 4352872, 422 681, 536 231, 536 253
Abstract:

Methods are provided for the preparation of polymer arrays on wafers wherein the wafers are rotated between synthesis steps to provide more uniform results across the entire wafer.

Antireflective Coatings For High-Resolution Photolithographic Synthesis Of Dna Arrays
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US Patent:

7332273, Feb 19, 2008
Filed:

Jun 20, 2002
Appl. No.:

10/177169
Inventors:

Mark Trulson - San Jose CA, US
Glenn H. McGall - Mountain View CA, US
Lisa T. Kajisa - San Jose CA, US
Dana Troung - San Jose CA, US
Assignee:

Affymetrix, Inc. - Santa Clara CA
International Classification:

C12Q 1/68
US Classification:

435 6
Abstract:

The present invention provides an array of polymers and methods of forming arrays of polymers by providing a substrate having a first layer including one or more dielectric coatings on a solid support and a second layer including a plurality of polymers disposed on the first layer. The invention also provides methods for forming an array of polymers on a substrate using light-directed synthesis by providing a substrate having a first layer including one or more dielectric coatings on a solid support; derivatizing the first layer by contacting the first layer with a silanation reagent, and a second layer disposed on said first layer wherein the second layer includes functional groups protected with a photolabile protecting group.

Antireflective Coatings For High-Resolution Photolithographic Synthesis Of Dna Arrays
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US Patent:

7790389, Sep 7, 2010
Filed:

Jan 16, 2008
Appl. No.:

12/014879
Inventors:

Mark O. Trulson - San Jose CA, US
Glenn H. McGall - Palo Alto CA, US
Lisa T. Kajisa - Palo Alto CA, US
Dana Truong - San Jose CA, US
Richard P. Rava - Redwood City CA, US
Martin J. Goldberg - Saratoga CA, US
Assignee:

Affymetrix, Inc. - Santa Clara CA
International Classification:

C12Q 1/68
US Classification:

435 6, 435 4
Abstract:

The present invention provides an array of polymers and methods of forming arrays of polymers by providing a substrate having a first layer including one or more dielectric coatings on a solid support and a second layer including a plurality of polymers disposed on the first layer. The invention also provides methods for forming an array of polymers on a substrate using light-directed synthesis by providing a substrate having a first layer including one or more dielectric coatings on a solid support, derivatizing the first layer by contacting the first layer with a silanation reagent, and a second layer disposed on said first layer wherein the second layer includes functional groups protected with a photolabile protecting group.

Antireflective Coatings For High-Resolution Photolithographic Synthesis Of Dna Array
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US Patent:

8114584, Feb 14, 2012
Filed:

Jul 8, 2010
Appl. No.:

12/832781
Inventors:

Mark O. Trulson - San Jose CA, US
Glenn H. McGall - Palo Alto CA, US
Lisa T. Kajisa - Palo Alto CA, US
Dana Truong - Sacramento CA, US
Rich P. Rava - Redwood City CA, US
Martin J. Goldberg - Saratoga CA, US
Assignee:

Affymetrix, Inc. - Santa Clara CA
International Classification:

C12Q 1/00
US Classification:

435 4
Abstract:

The present invention provides an array of polymers and methods of forming arrays of polymers by providing a substrate having a first layer including one or more dielectric coatings on a solid support and a second layer including a plurality of polymers disposed on the first layer. The invention also provides methods for forming an array of polymers on a substrate using light-directed synthesis by providing a substrate having a first layer including one or more dielectric coatings on a solid support, derivatizing the first layer by contacting the first layer with a silanation reagent, and a second layer disposed on said first layer wherein the second layer includes functional groups protected with a photolabile protecting group.

Phosphite Ester Oxidation In Nucleic Acid Array Preparation
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US Patent:

20050119473, Jun 2, 2005
Filed:

Oct 26, 2004
Appl. No.:

10/974287
Inventors:

Glenn McGall - Palo Alto CA, US
Lisa Kajisa - San Jose CA, US
Assignee:

Affymetrix, INC. - Santa Clara CA
International Classification:

C07H021/04
US Classification:

536025330
Abstract:

Methods are provided for preparing nucleic acid arrays on a support, particularly substantially planar supports. In one group of these methods a plurality of nucleic acids are synthesized on the support and the synthesis steps include oxidizing a phosphite triester nucleic acid linkage to a phosphate triester nucleic acid linkage using a solution about 0.005 M to about 0.05 M iodine in a mixture comprising water and organic solvent. In another group of these methods a plurality of nucleic acids are synthesized on the support and the synthesis steps include oxidizing a phosphite triester nucleic acid linkage to a phosphate triester nucleic acid linkage using a solution comprising iodine and at least 4% by volume of water.