Lisa S Karageozian

US Patent:

20200345805, Nov 5, 2020

Filed:

Apr 21, 2020

Appl. No.:

16/854818

Inventors:

- San Juan Capistrano CA, US
John Y. Park - Santa Ana CA, US
Vicken H. Karageozian - San Juan Capistrano CA, US
Melvin Arbis Sarayba - Ladera Ranch CA, US
Lisa S. Karageozian - San Juan Capistrano CA, US
Janine M. Aubel - Laguna Niguel CA, US

International Classification:

A61K 38/08
A61K 9/00
A61K 47/18
A61K 47/02
A61K 47/38

Abstract:

Compositions and methods for treating Dry Eye in a human or non-human animal subject wherein an effective amount of a pharmaceutical composition comprising an anti-integrin peptide is administered to an eye of the subject. The anti-integrin peptide may comprise a peptide which causes at least one effect selected from: reduced expression of the Complement 3 Receptor (Integrin αMβ2); reduced leucocyte adhesion; and reduced trans-endothelial leucocyte migration. The peptide may comprises Risuteganib.