Lisa Christine Simpson

US Patent:

6348507, Feb 19, 2002

Filed:

May 5, 1999

Appl. No.:

09/305609

Inventors:

David J. Heiler - Avon NY
Suzanne F. Groemminger - Rochester NY
John Denick, Jr. - Pittsford NY
Lisa C. Simpson - Rochester NY

Assignee:

Bausch Lomb Incorporated - Rochester NY

International Classification:

A61K 4700

US Classification:

514769

Abstract:

The present invention provides an optically clear, hydrophilic coating upon the surface of a silicone hydrogel lens by plasma treating the lens and subsequently heating the lens in an aqueous solution containing a surface-protective agent.

US Patent:

6790816, Sep 14, 2004

Filed:

Feb 13, 2001

Appl. No.:

09/782318

Inventors:

Erning Xia - Penfield NY
Lisa C. Simpson - Rochester NY

Assignee:

Bausch Lomb Incorporated - Rochester NY

International Classification:

C11D 348

US Classification:

510112, 510128, 510134, 510161, 510163

Abstract:

Contact lens cleaning compositions comprising preserved surfactant-containing solutions of a poly(oxypropylene)-poly(oxyethylene) adduct of ethylene diamine having a molecular weight from about 7500 to as high as 27,000 wherein at least 40 weight percent of the adduct is poly(oxyethylene) hydrophilic units. The solutions are effective in removing protein/lipid tear film deposits on both hard and soft contact lenses while providing a prophylactic-like action in retarding the formation of subsequent tear film deposits. The compositions provide effective cleaning and conditioning action using both ambient and high temperature disinfection methods.

US Patent:

20020182315, Dec 5, 2002

Filed:

May 7, 2002

Appl. No.:

10/140600

Inventors:

David Heiler - Avon NY, US
Lisa Simpson - Rochester NY, US
John Denick - Pittsford NY, US
Suzanne Groemminger - Rochester NY, US
Richard Smerbeck - Pittsford NY, US

International Classification:

B05D005/06
B05D003/02
B05D001/18

US Classification:

427/162000, 427/387000, 427/430100

Abstract:

The present invention provides an optically clear, hydrophilic coating upon the surface of a non-plasma treated hydrophobic hydrogel lens by heating the lens in an aqueous solution containing a surface-protective agent. Alternately, the non-plasma treated hydrophobic hydrogel lens may be subjected to ultrasonication while immersed in an aqueous solution containing a surface-protective agent.

US Patent:

20030133905, Jul 17, 2003

Filed:

Dec 9, 2002

Appl. No.:

10/314829

Inventors:

Zhenze Hu - Pittsford NY, US
Andrea Lever - Pittsford NY, US
Lisa Simpson - Rochester NY, US

International Classification:

A61K031/785
A61K031/717
A61K031/14

US Classification:

424/078310, 424/078380, 514/057000, 514/642000, 424/078320

Abstract:

A method of preventing and/or reducing deposition of denatured proteins on a contact lens while worn on the eye involves distilling in the eye an ophthalmically compatible composition including tromethamine in an amount effective to prevent or reduce protein denaturation. The compositions preferably include a demulcent, and may include conventional eye drop components such as a preservative, a buffering agent, a chelating agent, an osmolality adjusting agent, and/or a surfactant.

US Patent:

20030153475, Aug 14, 2003

Filed:

Dec 9, 2002

Appl. No.:

10/314753

Inventors:

Zhenze Hu - Pittsford NY, US
Andrea Lever - Pittsford NY, US
Lisa Simpson - Rochester NY, US

International Classification:

C11D001/00
B08B003/00

US Classification:

510/112000, 134/026000

Abstract:

A method for cleaning contact lenses employs a composition that includes tromethamine in an amount effective to reduce the amount of denatured protein on the contact lens, thus rendering the contact lenses easier to clean. Additionally, by soaking contact lenses in the composition prior to inserting the lens on the eye, the compositions provide a prophylactic effect in preventing protein denaturation while the contact lens is worn.

US Patent:

20060241001, Oct 26, 2006

Filed:

Jun 21, 2006

Appl. No.:

11/472233

Inventors:

Zhenze Hu - Pittsford NY, US
Andrea Lever - Pittsford NY, US
Lisa Simpson - Rochester NY, US

International Classification:

C11D 3/00

US Classification:

510112000

Abstract:

The present invention includes an ophthalmically acceptable composition comprising surfactants including poloxomine 1107 and poloxomer 407; and a biguanide antimicrobial agent in amount effective to disinfect a contact lens. The present invention also comprises a method of cleaning and disinfecting contact lenses using the ophthalmically acceptable composition set forth above.

US Patent:

6143244, Nov 7, 2000

Filed:

Nov 12, 1998

Appl. No.:

9/190690

Inventors:

Erning Xia - Penfield NY
Jill Short Rogalskyj - Livonia NY
Lisa C. Simpson - Rochester NY

Assignee:

Bausch & Lomb Incorporated - Rochester NY

International Classification:

A61L 200
A61L 900
A61L 1200
B08B 304
B08B 308

US Classification:

422 28

Abstract:

The present invention is directed to aqueous biguanide-containing disinfecting solutions containing an improved buffer system including both a phosphate and borate buffer. Preferred embodiments of the invention include methods and compositions for simultaneously cleaning and disinfecting contact lenses.

US Patent:

63096587, Oct 30, 2001

Filed:

Nov 12, 1998

Appl. No.:

9/190790

Inventors:

Erning Xia - Penfield NY
Lisa C. Simpson - Rochester NY
John Denick - Pittsford NY

Assignee:

Bausch & Lomb Incorporated - Rochester NY

International Classification:

A01N 2500
A61K 900
A61K 31155

US Classification:

424405

Abstract:

The present invention provides methods and compositions for cleaning and disinfecting contact lenses, which compositions comprise a carbonate or bicarbonate salt, a non-carbonate buffer system, an antimicrobial agent, and a non-ionic surfactant. Products according to the present invention, especially multi-purpose solutions, provide simultaneous disinfection and cleaning of contact lenses including the prevention or removal of protein and lipid deposits and other debris.