Mahesh I Desai

US Patent:

6340683, Jan 22, 2002

Filed:

Apr 22, 1999

Appl. No.:

09/296332

Inventors:

Mohammad R. Marzabadi - Ridgewood NJ
Stewart A. Noble - Upper Saddle River NJ
Mahesh N. Desai - Clifton NJ

Assignee:

Synaptic Pharmaceutical Corporation - Paramus NJ

International Classification:

C07D25150

US Classification:

514245, 544197, 544198, 544208, 544209

Abstract:

This invention is directed to triazine derivatives which are selective antagonists for a NPY (Y5) receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier.

US Patent:

6569856, May 27, 2003

Filed:

Jan 3, 2002

Appl. No.:

10/037859

Inventors:

Mohammad R. Marzabadi - Ridgewood NJ
Stewart A. Noble - Upper Saddle River NJ
Mahesh N. Desai - Clifton NJ

Assignee:

Synaptic Pharmaceutical Corporation - Paramus NJ

International Classification:

C07D25150

US Classification:

514245, 544197, 544198, 544208, 544209

Abstract:

This invention is directed to triazine derivatives which are selective antagonists for a NPY (Y5) receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier.

US Patent:

7189720, Mar 13, 2007

Filed:

Apr 6, 2005

Appl. No.:

11/099960

Inventors:

Mohammad R. Marzabadi - Ridgewood NJ, US
Stewart A. Noble - San Diego CA, US
Mahesh N. Desai - Nutley NJ, US

Assignee:

H. Lundbeck A/S - Valby-Copenhagen

International Classification:

C07D 251/50
C07D 251/70
A61K 31/53
A61P 3/04

US Classification:

514245, 544197, 544198, 544208, 544209

Abstract:

This invention is directed to triazine derivatives, bicyclic compounds and tricyclic compounds which are selective antagonists for a NPY (Y5) receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of this invention and a pharmaceutically acceptable carrier. This invention provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The invention further provides the use of a compound of the invention for the preparation of a pharmaceutical composition for treating an abnormality, wherein the abnormality is alleviated by decreasing the activity of a human Y5 receptor.

US Patent:

20040019050, Jan 29, 2004

Filed:

Apr 22, 2003

Appl. No.:

10/420238

Inventors:

Mohammad Marzabadi - Ridgewood NJ, US
Stewart Nobel - Upper Saddle River NJ, US
Mahesh Desai - Clifton NJ, US

Assignee:

Synaptic Pharmaceutical Corporation

International Classification:

A61K031/53
C07D251/18
C07D251/48
C 07D 4 3/02

US Classification:

514/245000, 544/204000, 544/209000

Abstract:

This invention is directed to triazine derivatives which are selective antagonists for a NPY (Y5) receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier.

US Patent:

20080045524, Feb 21, 2008

Filed:

Mar 12, 2007

Appl. No.:

11/716925

Inventors:

Mohammad Marzabadi - Ridgewood NJ, US
Wai Wong - Hamden CT, US
Stewart Noble - San Diego CA, US
Mahesh Desai - Nutley NJ, US

Assignee:

H. Lundbeck A/S - Valby-Copenhagen

International Classification:

A61K 31/53
A61K 31/426
A61K 31/5377
C07D 251/54
C07D 413/12
C07D 417/04
C07D 413/14
C07D 277/38
A61P 3/00
A61K 31/4436

US Classification:

514232200, 514236200, 514245000, 514342000, 514366000, 514370000, 544113000, 544197000, 544198000, 544083000, 546270400, 548151000, 548198000

Abstract:

This invention is directed to triazine derivatives, bicyclic compounds and tricyclic compounds which are selective antagonists for a NPY (Y5) receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of this invention and a pharmaceutically acceptable carrier. This invention provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The invention further provides the use of a compound of the invention for the preparation of a pharmaceutical composition for treating an abnormality, wherein the abnormality is alleviated by decreasing the activity of a human Y5 receptor.

US Patent:

48679860, Sep 19, 1989

Filed:

Jul 17, 1987

Appl. No.:

7/074935

Inventors:

Mahesh Desai - Hawthorne NJ
Frank Molinaro - West Orange NJ

Assignee:

Pharmachem Laboratories, Inc. - South Hackensack NJ

International Classification:

A61K 920

US Classification:

424464

Abstract:

Storage-stable, bio-available, free-flowing, microemulsified, Omega-three acid-containing oil compositions in the form of microspheres and macrospheres, said compositions consisting essentially of (1) up to about 70% by weight of Omega-three acid-containing oil, and (2) gelatin, in which the oil is microemulsified by the gelatin; processes for their preparation; and product applications (including tablet-type solid forms, dry powders, and spoonable, drinkable emulsions).