Maria D Escobar

US Patent:

8609144, Dec 17, 2013

Filed:

Jun 19, 2008

Appl. No.:

12/142083

Inventors:

James Burke - Santa Ana CA, US
Patrick M. Hughes - Aliso Viejo CA, US
Orilla C. Werhner - Anaheim CA, US
Ton C. Lin - Irvine CA, US
Maria Escobar - Foothill Ranch CA, US
Glenn Huang - Fremont CA, US
Kai-Ming Zhang - Irvine CA, US
Larry A. Wheeler - Irvine CA, US
Rosy S. Donn - Saratoga CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 9/00
A61K 31/498
A61P 27/02

US Classification:

424486, 424484, 514249

Abstract:

Biocompatible intraocular microspheres and implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat or to prevent the occurrence of one or more ocular conditions, to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like, to enhance normal retinal function and/or to lower intraocular pressure.

US Patent:

20050244506, Nov 3, 2005

Filed:

Apr 29, 2005

Appl. No.:

11/118519

Inventors:

James Burke - Santa Ana CA, US
Patrick Hughes - Aliso Viejo CA, US
Werhner Orilla - Anaheim CA, US
Ton Lin - Irvine CA, US
Maria Escobar - Foothill Ranch CA, US
Glenn Huang - Fremont CA, US
Kai-Ming Zhang - Irvine CA, US
Larry Wheeler - Irvine CA, US
Rosy Donn - Saratoga CA, US

Assignee:

ALLERGAN, INC. - Irvine CA

International Classification:

A61K031/498
A61K009/14

US Classification:

424489000, 514249000

Abstract:

Biocompatible intraocular microspheres and implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat or to prevent the occurrence of one or more ocular conditions, to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like, to enhance normal retinal function and/or to lower intraocular pressure.

US Patent:

20080299178, Dec 4, 2008

Filed:

Jun 19, 2008

Appl. No.:

12/142071

Inventors:

James Burke - Santa Ana CA, US
Patrick M. Hughes - Aliso Viego CA, US
Orilla C. Werhner - Anaheim CA, US
Ton Lin - Irvine CA, US
Maria Escobar - Foothill Ranch CA, US
Glenn Huang - Fremont CA, US
Kai-Ming Zhang - Irvine CA, US
Larry A. Wheeler - Irvine CA, US
Rosy S. Donn - Saratoga CA, US

Assignee:

ALLERGAN, INC. - Irvine CA

International Classification:

A61F 2/02
A61P 27/02

US Classification:

424428

Abstract:

Biocompatible intraocular microspheres and implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat or to prevent the occurrence of one or more ocular conditions, to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like, to enhance normal retinal function and/or to lower intraocular pressure.