Marianne Kearney - Watertown MA, US Jeffrey Isner - Weston MA, US Linda Isner - Weston MA, US
International Classification:
C12Q001/00 C12Q001/68
US Classification:
435/004000, 435/006000
Abstract:
The present invention provides novel methods for determining the bioactivity of a plasmid encoding for an endothelial cell mitogen. The invention also provides a method to optimize a plasmid construct for use in a gene therapy procedure. Further, the invention provides a quantitative quality control assay for evaluating a batch of plasmid DNA prior to use in a gene therapy treatment.