Jun 2010 to 2000 Health Science ConsultantMERCK & COMPANY
Jun 2006 to Jun 2010 Customer Representative II- CVANALYTICAL BIOLOGICAL SERVICES Wilmington, DE Sep 2005 to Feb 2006 Research AssociateTAPESTRY PHARMACEUTICALS
Jun 2004 to Dec 2004 Research Associate III- Diagnostics, Genomics GroupCONCURRENT PHARMACEUTICALS Fort Washington, PA Jan 2003 to Jun 2004 Research Associate III- Biochemistry, R & DBRISTOL MYERS SQUIBB Wilmington, DE 1998 to 2004 Associate Research Scientist IIBRISTOL MYERS SQUIBB Wilmington, DE 2002 to 2002 Molecular BiologistBRISTOL MYERS SQUIBB Wilmington, DE 1999 to 2002 Staff ScientistBRISTOL MYERS SQUIBB Wilmington, DE 1998 to 1999 Staff Scientist
Education:
Lehigh University Bethlehem, PA 2004 M.S. in Molecular BiologyThe University of Delaware Newark, DE 1999 B.A. in BiologyDelaware Tech. & Comm. College Wilmington, DE 1995 A.S.
Us Patents
Supported Polydiacetylene 3-D Arrays For Flourescent Or Phosphorescent Detection
Mary Reppy - Wilmington DE, US Bradford Pindzola - Wilmington DE, US Bethel Sharma - Wilmington DE, US Marianne Zecher - Wilmington DE, US
Assignee:
Analytical Biological Services, Inc. - Wilmington DE
International Classification:
C12Q 1/70 C12Q 1/68 G01N 33/53 C12M 3/00
US Classification:
435005000, 435006000, 435007100, 435287200
Abstract:
Supported three-dimensional arrays of a polydiacetylene backbone bonded to and supported by a solid support in a sample are provided. The bonding is achieved by providing a support having thiol and/or amine groups and epoxy groups and/or maleimide groups, and a polydiacetylene backbone containing the other of thiol and/or amine groups or the epoxy and/or maleimide groups for reacting with the corresponding thiol groups or epoxy groups and/or maleimide groups on the support; provided that when an amine is used the other group is an epoxy; and/or having a layer of a polyelectrolyte on the support; and/or having a multiple atom linker between the three-dimensional array of the polydiacetylene backbone and the solid support. The supported three-dimensional arrays can be used for detecting an analyte; for evaluating the organic/water partition coefficient and/or oral absorptivity and/or ability of a compound to diffuse into cell membranes and/or transcellular permeability properties of a compound and/or the ionization state of a compound and/or the volume of distribution of a compound and/or the distribution of a compound into different tissues and/or the partitioning of a compound into cell organelles by monitoring the change in the fluorescence or phosphorescence upon exposure to the compound and optionally comparing it to a known change in fluorescence or phosphorescence, respectively. The supported three-dimensional arrays can also be used to evaluate the ability of a compound to bind to a protein and for the detection of a plurality of different species.
Youtube
Marianne Williamson: Why You're So Sad
More and more people, in America and around the world, are reporting t...
Duration:
16m 52s
The Mother That Killed Her Daughter's Murdere...
... worst experience a parent can endure on march the 6th 1981 mariann...
Duration:
9m 44s
La Marianne & La Bourre Des Pommes, by Bistro...
La Marianne & La Bourre Des Pommes, by Bistro Moustache, recorded live...
Duration:
3m 57s
Faller 151054 Frhliche Zecher
Faller 151054 Frhliche Zecher 1:87 erhltlich bei .
Duration:
28s
Hermann Leopoldi Ich bin ein stiller Zecher
Duration:
3m 21s
Matthias Bitzer: A Different Sort of Gravity ...
A Different Sort of Gravity at Marianne Boesky Gallery in New York Cit...