The present invention provides diagnostic and prognostic methods for predicting the effectiveness of treatment of a cancer patient with a DHODH inhibitor or an antimetabolite. Methods are provided for predicting the sensitivity of tumor cell growth to inhibition by a DHODH inhibitor or an antimetabolite, comprising assessing whether the tumor cell comprises a mutant IDH gene or protein whereby cells that comprise a mutant IDH gene or protein are sensitive to inhibition by DHODH inhibitors and antimetabolites.
Long Beach, CAVP, Product Development at Retention Education Past: Director of Training at K12, Inc, Senior Instructional Designer at eMind, Training Manager...
Ricky Loponto, Elizabeth Beth, Lori Williams, Beth Oliver, Sharon Gower, Ellen Broderick, Teresa Moquin, Kathleen Berben, Elizabeth Attila, Deborah Kindlon