Mark Blakefield Catlin

US Patent:

7894870, Feb 22, 2011

Filed:

Aug 23, 2004

Appl. No.:

10/925074

Inventors:

Joseph Y. Lucisano - San Diego CA, US
Mark B. Catlin - San Diego CA, US

Assignee:

Glysens, Incorporated - San Diego CA

International Classification:

A61B 5/00

US Classification:

600345, 600347

Abstract:

At least one conductor is formed at a preselected location on a substrate made of a first insulating material having a high temperature resistance. The conductor is made from a solidified electrically conductive thick film material. A coating made of a second insulating material is formed over the substrate to hermetically seal at least a portion of the conductor. An exposed distal region of the conductor provides a detection electrode. The conductor has a reduced porosity that inhibits migration of fluid or constituents thereof through the conductor.

US Patent:

20050059871, Mar 17, 2005

Filed:

Oct 31, 2003

Appl. No.:

10/698911

Inventors:

David Gough - Cardiff CA, US
Michael Jablecki - La Jolla CA, US
Joseph Lucisano - San Diego CA, US
Mark Catlin - San Diego CA, US

International Classification:

A61B005/05

US Classification:

600347000

Abstract:

A tissue-implantable sensor for measurement of solutes in fluids and gases, such as oxygen and glucose, is provided. The sensor includes a multiplicity of detectors, constructed and arranged to improve the probability that one or more detectors will have access to a vascular source at points in time sufficient to permit accurate measurements to be taken. Means and methods for calculating solute levels using the sensor device of the invention are also provided.

US Patent:

20080033272, Feb 7, 2008

Filed:

Jun 26, 2007

Appl. No.:

11/823477

Inventors:

David Gough - Cardiff CA, US
Michael Jablecki - La Jolla CA, US
Joseph Lucisano - San Diego CA, US
Mark Catlin - San Diego CA, US

International Classification:

A61B 5/05

US Classification:

600347000

Abstract:

A tissue-implantable sensor for measurement of solutes in fluids and gases, such as oxygen and glucose, is provided. The sensor includes a multiplicity of detectors, constructed and arranged to improve the probability that one or more detectors will have access to a vascular source at points in time sufficient to permit accurate measurements to be taken. Means and methods for calculating solute levels using the sensor device of the invention are also provided.

US Patent:

20110137142, Jun 9, 2011

Filed:

Feb 9, 2011

Appl. No.:

13/024209

Inventors:

Joseph Y. Lucisano - SanDiego CA, US
Mark B. Catlin - San Diego CA, US

International Classification:

A61B 5/1473

US Classification:

600347

Abstract:

At least one conductor is formed at a preselected location on a substrate made of a first insulating material having a high temperature resistance. The conductor is made from a solidified electrically conductive thick film material. A coating made of a second insulating material is formed over the substrate to hermetically seal at least a portion of the conductor. An exposed distal region of the conductor provides a detection electrode. The conductor has a reduced porosity that inhibits migration of fluid or constituents thereof through the conductor.

US Patent:

20130197332, Aug 1, 2013

Filed:

Jul 26, 2012

Appl. No.:

13/559475

Inventors:

Joseph Y. Lucisano - San Diego CA, US
Mark B. Catlin - Lake Oswego OR, US
William J. Choi - San Diego CA, US
Payton C. Chu - San Diego CA, US
Joe T. Lin - San Diego CA, US
Timothy L. Routh - San Diego CA, US
Thomas G. Wallner - San Marcos CA, US

International Classification:

A61B 5/1473
A61B 5/145

US Classification:

600345, 600309, 600365, 600364, 29428, 29825

Abstract:

A tissue-implantable sensor for measurement of solutes in fluids and gases, such as oxygen and glucose, is provided. The sensor includes: i) a detector array including at least one detector; ii) a telemetry transmission portal; iii) an electrical power source; and iv) circuitry electrically connected to the detector array including signal processing means for determining an analyte level, such as glucose level, in a body fluid contacting the detectors. The sensor components are disposed in a hermetically sealed housing having a size and shape suitable for comfortable, safe, and unobtrusive subcutaneous implantation allowing for in vivo detection and long term monitoring of tissue glucose concentrations by wireless telemetry.

US Patent:

20200037932, Feb 6, 2020

Filed:

Oct 14, 2019

Appl. No.:

16/601346

Inventors:

- San Diego CA, US
Mark B. Catlin - San Diego CA, US
William J. Choi - San Diego CA, US
Payton C. Chu - San Diego CA, US
Joe T. Lin - San Diego CA, US
Timothy L. Routh - San Diego CA, US
Thomas G. Wallner - San Diego CA, US

International Classification:

A61B 5/1473
A61B 5/1486
A61B 5/145
A61B 5/07
A61B 5/00

Abstract:

A tissue-implantable sensor for measurement of solutes in fluids and gases, such as oxygen and glucose, is provided. The sensor includes: i) a detector array including at least one detector; ii) a telemetry transmission portal; iii) an electrical power source; and iv) circuitry electrically connected to the detector array including signal processing means for determining an analyte level, such as glucose level, in a body fluid contacting the detectors. The sensor components are disposed in a hermetically sealed housing having a size and shape suitable for comfortable, safe, and unobtrusive subcutaneous implantation allowing for in vivo detection and long term monitoring of tissue glucose concentrations by wireless telemetry.

US Patent:

20190246957, Aug 15, 2019

Filed:

Jan 24, 2019

Appl. No.:

16/256939

Inventors:

- San Diego CA, US
Mark B. Catlin - Lake Oswego OR, US
William J. Choi - San Diego CA, US
Payton C. Chu - San Diego CA, US
Joseph T. Lin - San Diego CA, US
Timothy L. Routh - San Diego CA, US
Thomas G. Wallner - San Marcos CA, US

International Classification:

A61B 5/1473
A61B 5/145
A61B 5/00
A61B 5/07
A61B 5/1486

Abstract:

A tissue-implantable sensor for measurement of solutes in fluids and gases, such as oxygen and glucose, is provided. The sensor includes: i) a detector array including at least one detector; ii) a telemetry transmission portal; iii) an electrical power source; and iv) circuitry electrically connected to the detector array including signal processing means for determining an analyte level, such as glucose level, in a body fluid contacting the detectors. The sensor components are disposed in a hermetically sealed housing having a size and shape suitable for comfortable, safe, and unobtrusive subcutaneous implantation allowing for in vivo detection and long term monitoring of tissue glucose concentrations by wireless telemetry.

US Patent:

20180348154, Dec 6, 2018

Filed:

Aug 6, 2018

Appl. No.:

16/055547

Inventors:

- San Diego CA, US
Mark B. Catlin - San Diego CA, US

International Classification:

G01N 27/12

Abstract:

At least one conductor is formed at a preselected location on a substrate made of a first insulating material having a high temperature resistance. The conductor is made from a solidified electrically conductive thick film material. A coating made of a second insulating material is formed over the substrate to hermetically seal at least a portion of the conductor. An exposed distal region of the conductor provides a detection electrode. The conductor has a reduced porosity that inhibits migration of fluid or constituents thereof through the conductor.