Mark C Elliot

US Patent:

7705596, Apr 27, 2010

Filed:

May 19, 2008

Appl. No.:

12/154012

Inventors:

Walter R. T. Witschey - Philadelphia PA, US
Ari Borthakur - Philadelphia PA, US
Mark A. Elliot - Bryn Mawr PA, US
Ravinder Reddy - Gladwyne PA, US

Assignee:

The Trustees of the University of Pennsylvania - Philadelphia PA

International Classification:

G01V 3/00

US Classification:

324309

Abstract:

Methods of, and systems for, simultaneously compensating for external-magnetic-field inhomogeneity as well as radiofrequency magnetic-field inhomogeneity in an MRI system. In one method embodiment, a pulse sequence is applied when the transmitter-reference frequency is delivered on resonance. The pulse sequence includes radiofrequency pulses which may be applied at arbitrary-excitation-flip angles that are not necessarily 90 degrees. The pulse sequence also includes spin-locking pulses applied in concert with a refocusing-composite pulse. In another method embodiment, a pulse sequence is applied when the transmitter-reference frequency is delivered off resonance. This off-resonance-pulse sequence includes radiofrequency pulses which may be applied at arbitrary-excitation-flip angles that are not necessarily 90 degrees. Sandwiched between the excitation-flip angles are at least two off-resonance-spin-lock pulses applied at an inverse phase and frequency from each other.

US Patent:

20170285124, Oct 5, 2017

Filed:

Sep 8, 2015

Appl. No.:

15/509402

Inventors:

- Philadelphia PA, US
Luke Macyszyn - Philadelphia PA, US
Emmanuel Caruyer - Rennes cedex, FR
Jeremy Lecoeur - Philadelphia PA, US
Mark Elliot - Bryn Mawr PA, US
Steven Brem - Haverford PA, US

International Classification:

G01R 33/563
G01R 33/56

Abstract:

Edema invariant tractography methods are provided. The methods include acquiring data using a multishell, high angular resolution diffusion imaging sequence; (ii) modeling the data using a multi-compartment model; and (iii) reconstructing the fibers through a probabilistic tracking algorithm using a fiber orientation distribution which has streamlines fitted to the output of said probabilistic tracking algorithm.