Mark W Read

US Patent:

6613718, Sep 2, 2003

Filed:

Dec 5, 2001

Appl. No.:

10/001816

Inventors:

Sandeep Gupta - Concord OH
Masamitsu Tsukamoto - Mayfield Heights OH
Mark Read - Willoughby OH

Assignee:

Ishihara Sangyo Kaisha, Ltd. - Osaka

International Classification:

C07D23934

US Classification:

504242, 504243, 544309, 544317, 544180, 544182, 544224, 5483601, 5483561

Abstract:

Substituted aryl ether derived compounds represented by the general structure (I) are described. X and Y are independent of each other and are represented by hydrogen, halogen, cyano, nitro, (C )alkyl, (C )haloalkyl, or (C )haloalkoxy; Z is oxygen or sulfur; Q is selected form Q1 to Q6; A is oxygen, sulfur, or imino; R is hydrogen, (C )alkyl, (C )haloalkyl, or amino and can be independent of each other in a single molecule; R and R are independent of each other and may be selected from the group consisting of hydrogen, halogen, cyano, nitro, (C )alkyl, (C )haloalkyl, (C )alkenyl, (C )haloalkenyl and amino which may be optionally substituted with (C )alkyl or (C )haloalkyl; Ar is substituted or unsubstituted carbocyclic or heterocyclic aromatic ring being at least a five or six membered ring. This ring can be fused with another substituted or unsubstituted five or six membered carbocyclic or heterocyclic ring. When Q is Q5, unsubstituted or substituted phenyl is excluded.

US Patent:

6617282, Sep 9, 2003

Filed:

Sep 26, 2001

Appl. No.:

09/962081

Inventors:

Mark Read - Willoughby OH
Masamitsu Tsukamoto - Mayfield Heights OH
Sandeep Gupta - Concord OH

Assignee:

Ishihara Sangyo Kaisha, Ltd. - Osaka

International Classification:

C07D23954

US Classification:

504243, 544296, 544310, 544312

Abstract:

A process for producing 3-phenyl-2,4(1H,3H)-pyrimidinediones having the general formula I and their salts which comprises reacting the isocyanates represented by the general formula (II) and the substituted hydrazono esters represented by the general formula (III) in the presence of a base. These compounds are useful as herbicides, defoliants and desiccants.

US Patent:

6770597, Aug 3, 2004

Filed:

Jul 17, 2002

Appl. No.:

10/196220

Inventors:

Masamitsu Tsukamoto - Moriyama, JP
Mark Read - Willoughby OH

Assignee:

Ishihara Sangyo Kaisha, Ltd. - Osaka

International Classification:

C07D23112

US Classification:

504243, 504280, 544311, 544312, 5483701, 5483751

Abstract:

The compound of the formula: wherein Y, X, Z, T and Q are defined in the specification,.

US Patent:

6927193, Aug 9, 2005

Filed:

Mar 3, 2003

Appl. No.:

10/376621

Inventors:

Sandeep Gupta - Concord OH, US
Masamitsu Tsukamoto - Mayfield Heights OH, US
Mark Read - Willoughby OH, US

Assignee:

Ishihara Sangyo Kaisha, Ltd. - Osaka

International Classification:

C07D239/56
C07D239/58
C07D239/47
A01N043/54

US Classification:

504243, 544309, 544318, 544319, 544320

Abstract:

Substituted aryl ether derived compounds represented by the general structure (I) are described. X and Y are independent of each other and are represented by hydrogen, halogen, cyano, nitro, (C)alkyl, (C)haloalkyl, or (C)haloalkoxy; Z is oxygen or sulfur; Q is selected form Q1 to Q6; Also described are the processes for the manufacture of these compounds and agriculturally suitable compositions containing these as active ingredients which are useful as herbicides for general or selective pre-emergent or post-emergent control of undesired plant species and defoliants.

US Patent:

20040267014, Dec 30, 2004

Filed:

Aug 20, 2004

Appl. No.:

10/491337

Inventors:

Sandeep Gupta - Concord OH, US
Masamitsu Tsukamoto - Moriyama-shi, JP
Mark Read - Willoughby OH, US

International Classification:

C07D471/02
C 07D 4 3/02
C07D231/14

US Classification:

544/182000, 544/222000, 544/238000, 544/239000, 544/309000, 544/310000, 546/119000, 548/366100

Abstract:

Substituted aryl ether derived compounds represented by general structure (I) are described. X and Y are independent of each other and are represented by hydrogen, halogen, cyano, nitro, (C)alkyl, (C)haloalkyl, or (C)haloalkoxy; Z is oxygen or sulfur, Q is selected form Q1 to Q6; A is oxygen, sulfur, or imino; Ris hydrogen, (C)alkyl, (C)haloalkyl, or amino and can be independent of each other in a single molecule; Rand Rare independent of each other and may be selected from the group consisting of hydrogen, halogen, cyano nitro, (C)alkyl, (C)haloalkyl, (C)alkenyl, (C)haloalkenyl and amino which may be optionally substituted with (C)alkyl or (C)haloalkyl; Ar is substituted or unsubstituted carbocyclic or heterocyclic aromatic ring being at least a five or six membered ring. This ring can be fused with another substituted or unsubstituted five or six membered carbocyclic or heterocyclic ring. When Q is Q5, unsubstituted or substituted phenyl is excluded. Also described are the processes for the manufacture of these compounds and argiculturally suitable compositions containing these as active ingredients which are useful as herbicides for general or selective pre-emergent or post-emergent control of undesired plant species and defoliants.

US Patent:

20050221990, Oct 6, 2005

Filed:

Jul 14, 2003

Appl. No.:

10/521315

Inventors:

Masamitsu Tsukamoto - Moriyama-shi, JP
Mark Read - Big Spring TX, US

International Classification:

A01N043/52
A01N043/40

US Classification:

504251000, 546278100, 546268100, 546270100, 504276000

Abstract:

The compound of the formula wherein Y, X, Z, T and Q are defined in the specification.

US Patent:

20220273639, Sep 1, 2022

Filed:

Mar 10, 2022

Appl. No.:

17/691989

Inventors:

- Copenhagen N, DK
Mark READ - Greenville SC, US
Elisabeth Vang CARSTENSEN - Farum, DK
Marco POPPE - Linz, AT
Andreas PELZ - Freistadt, AT

International Classification:

A61K 31/4545
A61K 9/20
A61K 9/50

Abstract:

The present disclosure relates to a process for preparing arimoclomol, arimoclomol citrate and key intermediates, such as ORZY-01, thereof. The disclosure further relates to a process for preparing high purity arimoclomol citrate and methods of using the same.