Martin H Bluth

US Patent:

7445889, Nov 4, 2008

Filed:

May 5, 2004

Appl. No.:

10/555958

Inventors:

Kevin D. Norowitz - Brooklyn NY, US
Martin H. Bluth - West Hempstead NY, US
Helen G. Durkin - Manhasset NY, US

Assignee:

The Research Foundation of State University of New York - Albany NY

International Classification:

C12Q 1/70
G01N 33/00
G01N 33/53
C12N 7/00

US Classification:

435 5, 435 71, 435 792, 4352351

Abstract:

The present invention provides a method for diagnosing a subject suffering a pathological condition characterized by parvovirus infection by detecting the presence of IgE anti-Parvovirus B 19 antibodies.

US Patent:

7604801, Oct 20, 2009

Filed:

Oct 16, 2008

Appl. No.:

12/252900

Inventors:

Kevin D. Norowitz - Brooklyn NY, US
Martin H. Bluth - West Hempstead NY, US
Helen G. Durkin - Manhasset NY, US

Assignee:

The Research Foundation of State University of New York - Albany NY

International Classification:

A61K 39/42
A61K 39/00
A61K 39/395
C07K 16/08

US Classification:

4241591, 4241301, 5303894

Abstract:

The present invention provides a method for diagnosing a subject suffering a pathological condition characterized by parvovirus infection by detecting the presence of IgE anti-Parvovirus B 19 antibodies.

US Patent:

7649113, Jan 19, 2010

Filed:

Aug 25, 2008

Appl. No.:

12/197401

Inventors:

Helen G. Durkin - Manhasset NY, US
Martin H. Bluth - West Hempstead NY, US
Rauno Joks - Port Washington NY, US
Alexander Kiselyov - San Diego CA, US

Assignee:

The Research Foundation of State University of New York - Albany NY

International Classification:

C07C 233/00

US Classification:

564188, 564191

Abstract:

The present invention is directed to novel compounds which are derivatives of minocycline or doxycycline, pharmaceutical compositions containing same and use thereof in lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic.

US Patent:

8012928, Sep 6, 2011

Filed:

Dec 18, 2009

Appl. No.:

12/642263

Inventors:

Martin H. Bluth - Southfield MI, US
Michael Zenilman - Lawrence NY, US

Assignee:

The Research Foundation of State University of New York - Albany NY

International Classification:

A61K 38/00
C12P 21/06
C07K 14/00

US Classification:

514 11, 435 691, 530300, 530350

Abstract:

A method of treating pancreatitis is provided, including the steps of: providing a mammal having pancreatitis; and administering a therapeutically effective amount of a truncated N-terminal PAP2; and making of an antibody specifically directed to detect PAP2.

US Patent:

8187810, May 29, 2012

Filed:

May 7, 2008

Appl. No.:

12/116307

Inventors:

Martin Heath Bluth - West Hempstead NY, US
Wellman W. Cheung - Briarwood NY, US

International Classification:

C12Q 1/68

US Classification:

435 611, 435 61

Abstract:

Techniques for diagnosing overactive bladder (OAB) in a patient are provided. For example, a technique for diagnosing overactive bladder in a patient includes the step of obtaining peripheral blood mononuclear cells (PBMC) from the patient to provide a reporter function in the patient.

US Patent:

20040219143, Nov 4, 2004

Filed:

Apr 30, 2003

Appl. No.:

10/426334

Inventors:

Martin Bluth - Brooklyn NY, US

International Classification:

A61K039/395

US Classification:

424/131100

Abstract:

Techniques for immunotherapy are provided. The techniques provide: 1) a method for the treatment of a patient, comprising the steps of obtaining recombinant Fc fragments; and providing the recombinant Fc fragments for treatment of the patient; 2) a method for the treatment of a patient having an autoimmune disease, comprising the steps of obtaining recombinant Fc fragments of immunoglobulin G; and providing the recombinant Fc fragments of immunoglobulin G for treatment of the patient having the autoimmune disease; 3) a method for the treatment of a patient having an atopic disease, comprising the steps of obtaining Fc fragments of immunoglobulin G; and providing the Fc fragments of immunoglobulin G for treatment of the patient having the atopic disease; and 4) a method for the treatment of a human, comprising the steps of obtaining Fc fragments; and providing the Fc fragments for treatment of the human.

US Patent:

20060128675, Jun 15, 2006

Filed:

Aug 8, 2003

Appl. No.:

10/523856

Inventors:

Helen Durkin - Manhasset NY, US
Rauno Joks - Port Washington NY, US
Martin Bluth - West Hempstead NY, US

International Classification:

A61K 31/65

US Classification:

514152000, 514154000

Abstract:

The present invention is directed to a method of lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic which method comprises administering to said mammal an IgE lowering effective amount of a tetracycline such as minocycline or doxycline. It is also directed to a method of monitoring the effectiveness of a drug in lowering the concentration of excess IgE in plasma in a mammal suffering from the disease in which IgE is pathogenic which method comprises making a first determination of the concentration of IgE in the plasma of said mammal at an initial time; administering to said mammal the drug; making a second determination of the concentration of IgE in the plasma of said mammal after the initial time and after administration of the drug and comparing the values obtained from the first and second determinations, such that if the value of the second determination is higher than or about the same as the value of the first determination and above a threshold level, then the dosage amount of the drug administered to the mammal is increased; otherwise the dosage amount is maintained.

US Patent:

20060235081, Oct 19, 2006

Filed:

Feb 9, 2004

Appl. No.:

10/544814

Inventors:

Helen Durkin - Manhasset NY, US
Martin Bluth - West Hempstead NY, US
Rauno Joks - Port Washington NY, US
Alexander Kiselyov - San Diego CA, US

International Classification:

A61K 31/16
A61K 31/13
A61K 31/12
C07C 237/18

US Classification:

514579000, 514613000, 514688000, 564188000, 568331000

Abstract:

The present invention is directed novel compounds which are derivatives of minocycline or doxycycline, pharmaceutical compositions containing same and use thereof in lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic.

Address:

22535 Coventry Wood Ln, Southfield, MI 48034

VIN:

2G1WB58N879109915

Make:

CHEVROLET

Model:

IMPALA

Year:

2007