- South San Francisco CA, US Timothy J. KAMERZELL - Overland Park KS, US Megan LI - San Francisco CA, US Mary CROMWELL - Redwood City CA, US Hong LIU - Foster City CA, US
The invention provides a stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, optionally, not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.0 to about 6.0, and an optional surfactant, methods for making such a formulation, and methods of using such a formulation.
- South San Francisco CA, US Timothy J. KAMERZELL - Overland Park KS, US Megan LI - San Francisco CA, US Mary CROMWELL - Redwood City CA, US Hong LIU - Foster City CA, US
The invention provides a stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, optionally, not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.0 to about 6.0, and an optional surfactant, methods for making such a formulation, and methods of using such a formulation.
- South San Francisco CA, US Timothy J. KAMERZELL - Overland Park KS, US Megan LI - San Francisco CA, US Mary CROMWELL - Redwood City CA, US Hong LIU - Foster City CA, US
International Classification:
C07K 16/22 A61J 1/20 A61J 1/14
Abstract:
The invention provides a stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, optionally, not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.0 to about 6.0, and an optional surfactant, methods for making such a formulation, and methods of using such a formulation.
- South San Francisco CA, US Timothy J. Kamerzell - Overland Park KS, US Megan Li - San Francisco CA, US Mary Cromwell - Redwood City CA, US Hong Liu - Foster City CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A61K 39/395 A61K 47/22 A61K 47/18
US Classification:
4241331, 4241301, 4241451, 4241581, 206525
Abstract:
The invention provides a stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, optionally, not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.0 to about 6.0, and an optional surfactant, methods for making such a formulation, and methods of using such a formulation.