The University of Texas Health Science Center at Houston
Professor and Director of Clinical and Translational Research
Rice University Jul 2009 - Aug 2016
Ralph and Dorothy Looney Professor of Biochemistry and Cell Biology, Department of Biosciences
Rice University Jul 2011 - Dec 2015
Vice Provost For Translational Bioscience
Rice University Jan 2011 - Dec 2015
Scientific Director, Bioscience Research Collaborative
Rice University Jul 2009 - Dec 2014
Ralph and Dorothy Chair of Biochemistry, Department of Biochemistry and Cell Biology
Education:
University of Texas M.d. Anderson Cancer Center 1983 - 1986
The Johns Hopkins University School of Medicine 1983 - 1983
Virginia Commonwealth University 1978 - 1982
Doctorates, Doctor of Philosophy, Biochemistry
University of South Carolina 1975 - 1978
Bachelors, Bachelor of Science, Biology
Skills:
Biochemistry Molecular Biology Cell Culture Cancer Translational Research Research Cell Biology Microscopy Laboratory Pcr Science Biotechnology Tissue Culture Western Blotting Confocal Microscopy Life Sciences Cancer Research Tissue Engineering
Languages:
Spanish
Us Patents
Delivery System For Heparin-Binding Growth Factors
A device comprising a scaffold coated with a protein having at least 83% identity to the amino acid sequence of the core protein of domain I of a mammalian perlecan, wherein at least one glycosaminoglycan is attached to the protein is described. The device may be used in vitro or in vivo to induce replication and/or differentiation of connective tissue cells and to repair tissue.
Perlecan Fragments As Biomarkers Of Bone Stromal Lysis
A method for the detection in a body fluid of perlecan polypeptide fragments that are biomarkers of tumor metastasis, and antibodies for detecting these fragments are described. An immunoassay kit for detecting the presence of these biomarkers in a body fluid, such as serum or urine, is also described.
Daniel D. Carson - Houston TX, US Mary C. Farach-Carson - Houston TX, US Weidong (William) Yang - Newark DE, US
Assignee:
University of Delaware - Newark DE
International Classification:
A61K 38/18 A61P 43/00 A61P 19/02
US Classification:
514 88, 514 76
Abstract:
Biomaterials providing sustained release of growth factor for repair of tissues such as bone and cartilage are disclosed. The biomaterials comprise a proteoglycan derived from domain I of perlecan and a growth factor, and, optionally, collagen.
Injectable Delivery System For Heparan-Binding Growth Factors
Catherine B. Safran - Bear DE, US Mary C. Farach-Carson - Houston TX, US Xinqiao Jia - Newark NJ, US Padma P. Srinivasa - Newark DE, US Amit Jha - Oakland CA, US
Assignee:
UNIVERSITY OF DELAWARE - Newaek DE
International Classification:
A61K 47/48 A61K 45/06 A61K 38/18
US Classification:
514 88, 514 76
Abstract:
A method for enhancing chondrogenesis in a subject in need thereof comprises administering to the subject an effective amount of a pharmaceutical composition comprising a growth factor bound to hyaluronic acid (HA)-based hydrogel particles (HGPs). The hyaluronic acid (HA)-based hydrogel particles (HGPs) are conjugated with a heparan sulfate proteoglycan (HSPG). Related medicaments and methods for preparing the medicaments are provided.
Implantable Modular Hydrogel For Salivary Gland Restoration
Implantable modular hydrogels to aid in salivary gland restoration and associated methods are provided. In one embodiment, the present disclosure provides for a hydrogel network comprising: a hyaluronic acid macromer crosslinked with a multiblock copolymer.
Name / Title
Company / Classification
Phones & Addresses
Mary Farach-Carson Assistant
HOUSTON AREA TRANSLATIONAL RESEARCH CONSORTIUM, IN