Mary A Patterson

US Patent:

8316666, Nov 27, 2012

Filed:

Jul 13, 2010

Appl. No.:

12/835598

Inventors:

Mary L Patterson - Buffalo Grove IL, US

International Classification:

A44C 9/00

US Classification:

63 154, 63 151

Abstract:

A frame member has two spaced apart parallel rings that are fixed to one another only at a first location. At a second location diametrically opposed to the first location each of the spaced apart parallel rings has a pedestal with a notch therein at an edge of the pedestal adjacent a space separating the parallel rings. The pedestals and notches are circumferentially aligned to cooperate with one another to provide a seat for seating an ornamental article therein. The securing member secures the ornamental article to the frame member. The securing member is a ring inserted in the space between the parallel rings of the frame member in a movable manner and is provided with a means for securing the ornamental article seated in the pedestals and notches of the frame member when the means for securing is aligned with the pedestals and notches of the frame member. The securing member may be moved with respect to the frame member to allow the ornamental article to be removed and replaced by another ornamental article, and then moved back to its original position with respect to the frame member to secure replacement ornamental article in place.

US Patent:

8479537, Jul 9, 2013

Filed:

Sep 16, 2012

Appl. No.:

13/621273

Inventors:

Mary L. Patterson - Buffalo Grove IL, US

International Classification:

A44C 9/00

US Classification:

63 154, 63 151

Abstract:

A frame member has two spaced apart parallel rings that are fixed to one another at a first location. At a second location diametrically opposed to the first location of the spaced apart parallel rings provide a seat for an ornamental article. A securing ring is disposed in the space between the parallel rings of the frame member and is fixed to the frame member by a pivot pin that is located nearer to the second location than to the first location. The securing ring is provided with a rigid wire that is aligned with the securing ring and is configured complimentary to a surface of the ornamental article for securing the ornamental article on the seat of the frame member. The securing ring pivots about the pivot pin to allow placement of the ornamental article on the seat and the removal of the ornamental article from the seat.

US Patent:

20130239611, Sep 19, 2013

Filed:

May 14, 2013

Appl. No.:

13/893488

Inventors:

MARY L. PATTERSON - Buffalo Grove IL, US

International Classification:

A44C 9/00

US Classification:

63 15

Abstract:

A frame member has two spaced apart parallel rings that are fixed to one another. Each of the spaced apart parallel rings has a pedestal with a notch therein at an edge of the pedestal adjacent a space separating the parallel rings. The pedestals and notches are circumferentially aligned and cooperate to provide a seat for seating a spherical ornamental article therein. A securing member secures the spherical ornamental article to the frame member. The securing member is a ring inserted in the space between the parallel rings of the frame member in a movable manner and is provided with a non-arcuate portion that is complementary to and secures the spherical ornamental article seated in the pedestals and notches of the frame member when the non-arcuate portion of the securing member is aligned with the pedestals and notches of the frame member. The securing member may be moved with respect to the frame member to allow the spherical ornamental article to be removed and replaced by another spherical ornamental article, and then moved back to its original position with respect to the frame member to secure the spherical ornamental article in place.

US Patent:

20200197532, Jun 25, 2020

Filed:

Nov 18, 2019

Appl. No.:

16/686708

Inventors:

- Memphis TN, US
John Marvin STUART - Memphis TN, US
Mary Christine PATTERSON - Cordova TN, US
Hongsik CHO - Germantown TN, US

Assignee:

UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION - Memphis TN

International Classification:

A61K 47/68
C12N 5/0775
C07K 16/28
A61K 9/51

Abstract:

Provided are methods and compositions to target delivery of cells to a tissue lesion, thereby treating the lesion. For example, biotinylated antibodies with affinity to a lesion epitope are administered at the lesion. Reparative cells including avidin and biotin are then administered at the lesion. The reparative cells are targeted to the lesion via avidin-biotin bridges to the antibodies, with additional cells recruited to the lesion via cell-to-cell avidin-biotin bridges. In certain examples, antibody-reparative cell complexes are formed by mixing the biotinylated antibodies with the reparative cells including avidin and biotin. The complexes are then administered at the lesion. In other examples, multivalent antibodies are used to target reparative cells to the lesion, such as by binding an epitope at the lesion and an epitope present on the reparative cell. In other examples, the antibodies are chemically linked to a reparative cell or to a nanosome containing a therapeutic agent.