David Raymond Graham - Baltimore MD, US Susan Christine Trow - Baltimore MD, US Mary Christine Zink - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
G01N 33/53
US Classification:
435 71, 436518
Abstract:
The present invention relates, e. g. , to a method for detecting a full-length protein and a truncated form (e. g. , a naturally occurring cleavage product) thereof, in a sample, comprisingIn one embodiment of the invention, the full-length protein is thioredoxin (TRX), and the truncated form thereof is its biologically active, C-terminal truncated, 10 kDa cleavage product, TRX 80.
Suppression Of Hiv Replication And Prevention And Treatment Of Hiv
Mary C. Zink - Ellicott City MD, US Sheila A. Barber - Walkersville MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61K 31/65
US Classification:
514154, 514152
Abstract:
The invention provides a new and effective treatment for human immunodeficiency diseases, particularly for HIV-infected individuals. The treatment utilizes tetracycline analogs, particularly minocycline, in amounts that are effective to prevent HIV replication both the central nervous system and in peripheral blood.
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