Mason M Yamashita

US Patent:

20180346907, Dec 6, 2018

Filed:

Nov 27, 2017

Appl. No.:

15/822692

Inventors:

- Carlsbad CA, US
Mason YAMASHITA - Carlsbad CA, US

Assignee:

Ionis Pharmaceuticals, Inc. - Carlsbad CA

International Classification:

C12N 15/113
C07K 14/47

Abstract:

In certain embodiments, methods, compounds, and compositions for treating B-cell lymphoma or hepatocellular carcinoma by inhibiting expression of STAT3 mRNA or protein in an animal are provided herein. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate B-cell lymphoma or hepatocellular carcinoma.

US Patent:

20170145413, May 25, 2017

Filed:

Nov 21, 2016

Appl. No.:

15/356947

Inventors:

- Carlsbad CA, US
Mason YAMASHITA - Carlsbad CA, US

Assignee:

Ionis Pharmaceuticals, Inc. - Carlsbad CA

International Classification:

C12N 15/113

Abstract:

In certain embodiments, methods, compounds, and compositions for treating B-cell lymphoma or hepatocellular carcinoma by inhibiting expression of ST AT3 mRNA or protein in an animal are provided herein. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate B-celllymphoma or hepatocellular carcinoma. The STAT (signal transducers and activators of transcription) family of proteins are DNA-binding proteins that play a dual role in signal transduction and activation of transcription.

US Patent:

20160002625, Jan 7, 2016

Filed:

Oct 30, 2013

Appl. No.:

14/439363

Inventors:

- Carlsbad CA, US
Mason YAMASHITA - Carlsbad CA, US

Assignee:

ISIS PHARMACEUTICALS INC. - Carlsbad CA

International Classification:

C12N 15/113
C07K 14/47

Abstract:

In certain embodiments, methods, compounds, and compositions for treating B-cell lymphoma or hepatocellular carcinoma by inhibiting expression of ST AT3 mRNA or protein in an animal are provided herein. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate B-cell lymphoma or hepatocellular carcinoma. The STAT (signal transducers and activators of transcription) family of proteins are DNA-binding proteins that play a dual role in signal transduction and activation of transcription.