Matthew John Heckert

US Patent:

20120042412, Feb 16, 2012

Filed:

Aug 12, 2011

Appl. No.:

13/208960

Inventors:

Henrik Albert - Alameda CA, US
Linda A. Castle - Mountain View CA, US
Matthew Heckert - Union City CA, US
Jian Lu - Union City IA, US
Daniel L. Siehl - Menlo Park CA, US
Yumin Tao - Urbandale IA, US

Assignee:

Pioneer Hi-Bred International, Inc. - Johnston IA

International Classification:

A01H 1/06
C12N 15/82
C12N 5/10
C12N 9/96
A01H 5/10
C07K 19/00
C12N 9/02
C12N 15/62
A01H 5/00

US Classification:

800278, 536 234, 536 232, 4353201, 435419, 435412, 435416, 435415, 800298, 530350, 435189, 435418, 435188

Abstract:

Chimeric polynucleotides comprising a nucleotide sequence encoding a chloroplast transit peptide operably linked to a heterologous polynucleotide of interest are provided, wherein the chloroplast transit peptide comprises an amino acid sequence having the chloroplast transit peptide sequence as set forth in SEQ ID NO:1 or a biologically active variant or fragment thereof or wherein the chloroplast transit peptide comprises the sequence set forth in SEQ ID NO: 58 or an active variant or fragment thereof. Chimeric polypeptides encoding the same, as well as, cells, plant cells, plants and seeds are further provided which comprise the chimeric polynucleotides. Compositions further include HPPD polypeptides and polynucleotides encoding the same as set forth in SEQ ID NOS: 57 and 60 or active variants and fragments thereof. Such sequences comprise the chloroplast transit peptide as set forth in SEQ ID NO: 58 or an active variants or fragments thereof. Cells, plant cells, plants and seeds are further provided which comprise such sequences. Methods of use of the various sequences are also provided.

US Patent:

20120042413, Feb 16, 2012

Filed:

Aug 12, 2011

Appl. No.:

13/208966

Inventors:

Henrik Albert - Alameda CA, US
Ericka R. Bermudez - Aptos CA, US
Linda A. Castle - Mountain View CA, US
Yuxia Dong - San Ramon CA, US
Matthew J. Heckert - Union City CA, US
Jingtong Hou - San Pablo CA, US
Zhenglin Hou - Ankeny IA, US
Jian Lu - Union City CA, US
Daniel L. Siehl - Menlo Park CA, US
Yumin Tao - Urbandale IA, US

Assignee:

Pioneer Hi-Bred International, Inc. - Johnston IA

International Classification:

C12N 15/82
C12N 15/63
C12N 5/10
A01H 5/00
A01H 5/10
C12N 9/02
C12Q 1/68
A01N 41/10
A01N 43/80
A01N 43/56
A01N 57/20
A01N 43/90
A01N 43/54
A01P 13/00
G01N 33/573
C12N 15/53

US Classification:

800278, 536 232, 4353201, 435419, 435413, 435415, 435416, 800300, 435189, 435468, 435 618, 504348, 504271, 504282, 504128, 504130, 504136, 504138, 504139, 504118, 435 74, 435 612

Abstract:

Compositions and methods comprising polynucleotides and polypeptides having 4-hydroxyphenylpyruvate dioxygenase (HPPD) activity and having insensitivity to an HPPD inhibitor are provided. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the HPPD sequences. Various methods of employing the HPPD sequences are provided. Such methods include, for example, methods for producing an HPPD inhibitor tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional HPPD variants. Further provided are various methods and compositions that allow the various HPPD polypeptides and variant and fragments thereof to be expressed in a chloroplast or transported to a chloroplast.

US Patent:

20080234130, Sep 25, 2008

Filed:

Aug 22, 2006

Appl. No.:

11/507751

Inventors:

Billy Fred McCutchen - College Station TX, US
Linda A. Castle - Mountain View CA, US
Timothy K. Chicoine - St. Charles IA, US
Jon S. Claus - Wilmington DE, US
Jerry M. Green - Landenberg PA, US
Anthony D. Guida - Newark DE, US
Christine B. Hazel - Port Deposit MD, US
Matthew J. Heckert - San Carlos CA, US
Jeffrey M. Hegstad - Ankeny IA, US
James M. Hutchison - Wilmington DE, US
Donglong Liu - Johnston IA, US
Albert L. Lu - Newark DE, US
Wayne J. Mehre - Urbandale IA, US
York Moy - San Francisco CA, US
Paul D. Olson - Kalaheo HI, US
Kenneth A. Peeples - Wilmington DE, US
David W. Saunders - Dallas Center IA, US
Mark D. Vogt - Ankeny IA, US
Jack Q. Wilkinson - Redwood City CA, US
James F. H. Wong - Johnston IA, US

Assignee:

Pioneer Hi-Bred International, Inc. - Johnston IA
E.I. du Pont de Nemours and Company - Wilmington DE

International Classification:

A01N 43/48
A01N 43/64
A01N 57/18
A01N 43/647
A01P 13/00
C12N 15/11
A01N 59/26

US Classification:

504128, 504130, 800278, 504187, 504227, 504261, 504235, 504209

Abstract:

Methods and compositions are provided related to improved plants that are tolerant to more than one herbicide. Particularly, the invention provides plants that are tolerant of glyphosate and are tolerant to at least one ALS inhibitor, and methods of use thereof. The glyphosate/ALS inhibitor-tolerant plants comprise a polynucleotide that encodes a polypeptide that confers tolerance to glyphosate and a polynucleotide that encodes an ALS inhibitor-tolerant polypeptide. In specific embodiments, a plant of the invention expresses a GAT polypeptide and an HRA polypeptide. Methods to control weeds, improve plant yield, and increase transformation efficiencies are provided.

US Patent:

20210002657, Jan 7, 2021

Filed:

Feb 28, 2019

Appl. No.:

16/977020

Inventors:

- JOHNSTON IA, US
MYEONG-JE CHO - SUNNYVALE CA, US
VIRGINIA CRANE - DES MOINES IA, US
MATTHEW J HECKERT - UNION CITY CA, US
JIAN JIN - WEST LAFAYETTE IN, US
TODD J JONES - JOHNSTON IA, US
KEVIN E MCBRIDE - DAVIS CA, US
JEANNE SANDAHL - WEST DES MOINES IA, US
SHIV BAHADUR TIWARI - SAN JOSE CA, US

Assignee:

PIONEER HI-BRED INTERNATIONAL, INC. - JOHNSTON IA

International Classification:

C12N 15/82
G01N 33/50
C12N 15/81
C12Q 1/06

Abstract:

Methods of detecting the impacts on plant health attributable to the presence of one or more agronomically important polypeptides of interest in a transgenic plant are disclosed. The methods involve transforming plants or plant cells with nucleic acid sequences encoding proteins of agronomically important traits. The transformed plants or plant cells expressing the nucleic acid sequences encoding the proteins of agronomically important traits are compared to transformed plants or plant cells expressing a neutral control gene to detect the impacts on plant health attributable to the presence of the one or more agronomically important polypeptides of interest.

US Patent:

20160017351, Jan 21, 2016

Filed:

Aug 25, 2015

Appl. No.:

14/835242

Inventors:

- Johnston IA, US
Linda A. Castle - Mountain View CA, US
Matthew Heckert - Union City CA, US
Jian Lu - Union City CA, US
Daniel L. Siehl - Menlo Park CA, US
Yumin Tao - Urbandale IA, US

International Classification:

C12N 15/82
C12N 9/02

Abstract:

Chimeric polynucleotides comprising a nucleotide sequence encoding a chloroplast transit peptide operably linked to a heterologous polynucleotide of interest are provided, wherein the chloroplast transit peptide comprises an amino acid sequence having the chloroplast transit peptide sequence as set forth in SEQ ID NO: 1 or a biologically active variant or fragment thereof or wherein the chloroplast transit peptide comprises the sequence set forth in SEQ ID NO: 58 or an active variant or fragment thereof. Chimeric polypeptides encoding the same, as well as, cells, plant cells, plants and seeds are further provided which comprise the chimeric polynucleotides. Compositions further include HPPD polypeptides and polynucleotides encoding the same as set forth in SEQ ID NOS: 57 and 60 or active variants and fragments thereof. Such sequences comprise the chloroplast transit peptide as set forth in SEQ ID NO: 58 or an active variants or fragments thereof. Cells, plant cells, plants and seeds are further provided which comprise such sequences. Methods of use of the various sequences are also provided.