Matthew Joseph Neal

US Patent:

20200319128, Oct 8, 2020

Filed:

Apr 1, 2020

Appl. No.:

16/837704

Inventors:

- Cleveland OH, US
- Pittsburgh PA, US
Anirban Sen Gupta - Cleveland OH, US
Matthew David Neal - Sewickley PA, US
Ujjal Didar Singh Sekhon - Cleveland OH, US
Sanjay Pitamber Ahuja - Cleveland Heights OH, US
Sina Pourang - Cleveland Heights OH, US
Debnath Maji - Ellsworth ME, US

International Classification:

G01N 27/22
G01N 33/49
G01N 27/02

Abstract:

As one example, an apparatus includes a dielectric microsensor comprising a microfluidic chamber that includes a capacitive sensing structure, the microfluidic chamber including a fluid input port to receive a volume of a blood sample. A bioactive agent is disposed within the chamber to interact with the volume of the blood sample received in the microfluidic chamber. A transmitter provides an input radio frequency (RF) signal to an RF input of the dielectric microsensor. A receiver receives an output RF signal from an RF output of the dielectric microsensor. A computing device that computes dielectric permittivity values of the sample that vary over a time interval based on the output RF signal, the computing device to provide an assessment of hemostatic dysfunction and associated coagulopathy based on the dielectric permittivity values.