Matthew James O'Donnell

US Patent:

6852082, Feb 8, 2005

Filed:

Jul 17, 2002

Appl. No.:

10/198429

Inventors:

Adam Strickberger - Ann Arbor MI, US
Charles Cain - Ann Arbor MI, US
Matthew O'Donnell - Ann Arbor MI, US

International Classification:

A61B008/14

US Classification:

600459, 128842

Abstract:

Apparatuses and methods for performing non-invasive vasectomies are provided. In a preferred embodiment, an apparatus according to the present invention comprises a main body defining a recess and an ultrasonic transducer disposed adjacent said recess and adapted to emit ultrasonic energy into said recess. A tissue clamp is removeably disposed in the recess and is adapted to receive parallel sections of a scrotum that include a portion of the vas deferens. The clamp is further adapted to position the vas deferens within an effective distance of the ultrasonic transducer. Also, the apparatus includes means for retaining the parallel sections and the vas deferens within the clamp during a procedure.

US Patent:

6867720, Mar 15, 2005

Filed:

Aug 27, 2003

Appl. No.:

10/649209

Inventors:

Steven R. Freeman - Ann Arbor MI, US
Matthew O'Donnell - Ann Arbor MI, US
Thomas E. Linnenbrink - Monument CO, US
Marc A. Morin - Woodland Park CO, US
Marshall K. Quick - Colorado Springs CO, US
Charles S. Desilets - Edmonds WA, US

Assignee:

The Regents of the University of Michigan - Ann Arbor MI

International Classification:

H03M003/00

US Classification:

341143, 341155, 341172, 341144

Abstract:

A method and apparatus are provided for reducing distortion in a dynamically delayed digital sample stream of an imaging system. The method includes the steps of delta-sigma modulating an input analog signal of the imaging system at a frequency above the Nyquist frequency of the input analog signal to generate a digital sample stream and changing a length of the sample stream to delay a portion of the sample stream while maintaining synchronism between a delta-sigma modulator and a demodulator of the system.

US Patent:

6987474, Jan 17, 2006

Filed:

Oct 26, 2004

Appl. No.:

10/973235

Inventors:

Steven R. Freeman - Ann Arbor MI, US
Matthew O'Donnell - Ann Arbor MI, US
Thomas E. Linnenbrink - Monument CO, US
Marc A. Morin - Woodland Park CO, US
Marshall K. Quick - Colorado Springs CO, US
Charles S. Desilets - Edmonds WA, US

Assignee:

Q-Dot, Inc. - Colorado Springs CO

International Classification:

H03M 3/00

US Classification:

341143, 341172, 341144

Abstract:

A method and apparatus are provided for reducing distortion in a dynamically delayed digital sample stream of an imaging system. The method includes the steps of delta-sigma modulating an input analog signal of the imaging system at a frequency above the Nyquist frequency of the input analog signal to generate a digital sample stream and changing a length of the sample stream to delay a portion of the sample stream while maintaining synchronism between a delta-sigma modulator and a demodulator of the system.

US Patent:

7318804, Jan 15, 2008

Filed:

Dec 9, 2003

Appl. No.:

10/731302

Inventors:

William F. Weitzel - Ypsilanti MI, US
Kang Kim - Ann Arbor MI, US
Matthew O'Donnell - Ann Arbor MI, US
Jonathan M. Rubin - Scio Township MI, US
Hua Xie - Ann Arbor MI, US
Xunchang Chen - Ann Arbor MI, US

Assignee:

The Regents of the University of Michigan - Ann Arbor MI

International Classification:

A61B 8/00

US Classification:

600438, 600443

Abstract:

Methods and systems for measuring mechanical property of a vascular wall and a method and system for determining health of a vascular structure are provided wherein local deformation of a vessel wall resulting from physiologic pressures with altered transmural forces is measured. A non-invasive free-hand ultrasound scanning-procedure was performed to apply external force, comparable to the force generated in measuring a subject's blood pressure, to achieve higher strains by equalizing the internal arterial baseline pressure. When the applied pressure matched the internal baseline diastolic pressure, strain and strain rate increased by a factor of 10 over a cardiac cycle. Radial arterial strain was assessed in the vessel wall over the entire deformation procedure using a phase-sensitive, two-dimensional speckle-tracking algorithm. An elastic modulus reconstruction procedure was developed to estimate the non-linear elastic properties of the vascular wall.

US Patent:

7367948, May 6, 2008

Filed:

Aug 19, 2003

Appl. No.:

10/643659

Inventors:

Matthew O'Donnell - Ann Arbor MI, US
Jing Yong Ye - Ann Arbor MI, US
Theodore B. Norris - Dexter MI, US
Lajos P. Balogh - Ann Arbor MI, US
Susanne M. Milas - Ann Arbor MI, US
Stanislav Y. Emelianov - Ann Arbor MI, US
Kyle W. Hollman - Fenton MI, US

Assignee:

The Regents of the University of Michigan - Ann Arbor MI

International Classification:

A61B 8/00
A61B 8/12
A61B 8/14
A61B 6/00
A61H 1/00

US Classification:

600458, 600437, 600438, 600439, 600473, 600476, 601 2

Abstract:

An acoustic monitoring method and system in laser-induced optical breakdown (LIOB) provides information which characterize material which is broken down, microbubbles in the material, and/or the microenvironment of the microbubbles. In one embodiment of the invention, femtosecond laser pulses are focused just inside the surface of a volume of aqueous solution which may include dendrimer nanocomposite (DNC) particles. A tightly focused, high frequency, single-element ultrasonic transducer is positioned such that its focus coincides axially and laterally with this laser focus. When optical breakdown occurs, a microbubble forms and a shock or pressure wave is emitted (i. e. , acoustic emission). In addition to this acoustic signal, the microbubble may be actively probed with pulse-echo measurements from the same transducer. After the microbubble forms, received pulse-echo signals have an extra pulse, describing the microbubble location and providing a measure of axial microbubble size.

US Patent:

7549985, Jun 23, 2009

Filed:

Jun 25, 2003

Appl. No.:

10/603341

Inventors:

Matthew O'Donnell - Ann Arbor MI, US

Assignee:

The Regents of the University of Michigan - Ann Arbor MI

International Classification:

A61B 18/18
G01N 3/00
G01N 3/30
G01N 7/00
G01M 3/02

US Classification:

606 10, 606 12, 73 1207, 73 1208, 73 37, 734321

Abstract:

A method and system to create and acoustically manipulate without destroying a microbubble which, in biological applications, can manipulate structures such as cells and subcellular structures at a nanoscopic scale.

US Patent:

7587105, Sep 8, 2009

Filed:

Sep 8, 2005

Appl. No.:

11/662154

Inventors:

Shai Ashkenazi - Ann Arbor MI, US
Lingjie Jay Guo - Ann Arbor MI, US
Matthew O'Donnell - Ann Arbor MI, US

Assignee:

The Regents Of The University Of Michigan - Ann Arbor MI

International Classification:

G02B 6/00

US Classification:

385 13

Abstract:

A polymer waveguide resonator device for high-frequency ultrasound detection having a optical resonator coupled to a straight optical waveguide which serves as input and output ports. Acoustic waves irradiating the waveguide induce strain modifying the waveguide cross-section or other design property. As a consequence, the effective refractive index of optical waves propagating along the ring is modified. The sharp wavelength dependence of the high Q-factor resonator enhances the optical response to acoustic strain. High sensitivity is demonstrated experimentally in detecting broadband ultrasound pulses from a 10 MHz transducer.

US Patent:

8107694, Jan 31, 2012

Filed:

Jul 20, 2007

Appl. No.:

11/781212

Inventors:

James Hamilton - Brighton MI, US
Matthew O'Donnell - Seattle WA, US

Assignee:

Ultrasound Medical Devices, Inc. - Ann Arbor MI

International Classification:

G06K 9/00

US Classification:

382128, 382131, 382132, 382103

Abstract:

In a first preferred embodiment, the invention includes a method of tracking displacements between ultrasound images by calculating a coarse displacement estimate, and calculating a fine displacement estimate using images and coarse displacement estimate. In a second preferred embodiment, the invention includes a method of calculating a coarse displacement estimate from images by reducing the resolution of the images, correlating the reduced resolution images, and calculating the location of the peak of the correlation function. In a third preferred embodiment, the invention includes a method of calculating a finer displacement estimate from images by using a coarse displacement estimate with correlation processing of the images and calculating the location of the peak value of the correlation function.