Matthew J Titlow

US Patent:

20230025435, Jan 26, 2023

Filed:

Jan 6, 2021

Appl. No.:

17/790905

Inventors:

- Millstone NJ, US
Matthew Titlow - Carlsbad CA, US
Hector L. Lopez - Cream Ridge NJ, US

Assignee:

JUVN3 Holdings, LLC - Millstone NJ

International Classification:

A61K 33/34
A61K 31/455
A61K 31/522
A61K 36/31

Abstract:

Compositions and methods are presented that help reduce cellular ageing, improve cellular stress resilience, and/or promote increased longevity. Exemplary compositions include a combination of a purine alkaloid, an isothiocyanate or thioglucoside, a metal-containing antioxidant, and optionally an additional ingredient, where the purine alkaloid, the isothiocyanate or thioglucoside, and the metal-containing antioxidant may be chemically isolated compounds or extracts or other preparations from naturally occurring entities such as plants, bacteria, yeast, etc. Advantageously, contemplated compositions are effective to reduce and repair oxidative stress, improve mitochondrial function, augment DNA repair and telomere maintenance, increase fatty acid metabolism, and modulate histone deacetylation. More specifically, the contemplated compositions are capable of increasing cellular vitality by inducing expression of OCT4, SOX, and/or KLF4 and/or decreasing biomarkers of cell senescence.

US Patent:

20210137928, May 13, 2021

Filed:

Oct 30, 2020

Appl. No.:

17/084777

Inventors:

- Morganville NJ, US
Tim N. Ziegenfuss - Chardon OH, US
Matthew Titlow - Carlsbad CA, US

Assignee:

Ortho-Nutra, LLC - Morganville NJ

International Classification:

A61K 31/522
C07D 487/04
A23L 33/10
A23L 33/105
A61K 31/133
A61K 31/14
A61K 31/4748
A61K 31/685
A61K 31/7048
A61K 31/7068

Abstract:

An enhanced caffeinated beverage composition includes a caffeinated drink combined with an effective blend of methylliberine and theacrine providing increased mood, energy, alertness, focus, motivation, and/or decreased fatigue without adversely affecting heart rate or blood pressure.

US Patent:

20200384042, Dec 10, 2020

Filed:

Jun 6, 2019

Appl. No.:

16/434051

Inventors:

- Carlsbad CA, US
Matthew Titlow - Carlsbad CA, US

International Classification:

A61K 35/745
A61K 31/194
A61K 9/00

Abstract:

Tributyrin and/or tributyrin derivatives are used to selectively increase the levels of in the gut. In preferred methods, the tributyrin and/or tributyrin derivatives are orally administered alone or in combination with a food item or other nutritionally acceptable carrier, and may further include . Tributyrin-enhanced strains are also contemplated that include previously cultured in tributyrin and/or tributyrin derivatives.

US Patent:

20200384043, Dec 10, 2020

Filed:

Jul 23, 2019

Appl. No.:

16/519434

Inventors:

- Carlsbad CA, US
Matthew Titlow - Carlsbad CA, US

International Classification:

A61K 35/745
A61K 9/00
A61K 31/194

Abstract:

Tributyrin and/or tributyrin derivatives are used to selectively increase the levels of in the gut. In preferred methods, the tributyrin and/or tributyrin derivatives are orally administered alone or in combination with a food item or other nutritionally acceptable carrier, and may further include Tributyrin-enhanced strains are also contemplated that include previously cultured in tributyrin and/or tributyrin derivatives.