Matthew T Walters

US Patent:

20220211701, Jul 7, 2022

Filed:

Mar 27, 2020

Appl. No.:

17/599472

Inventors:

- Hayward CA, US
Devika Ashok - Belmont CA, US
Daniel M. DiRenzo - Palo Alto CA, US
Akshata R. Udyavar - Foster City CA, US
Matthew J. Walters - Pacifica CA, US
Stephen W. Young - Palomar Park CA, US

Assignee:

ARCUS BIOSCIENCES, INC. - Hayward CA

International Classification:

A61K 31/506
A61K 31/706
A61K 31/7076
A61K 45/06

Abstract:

The present disclosure provides methods of treating a cancer in a subject having an established adenosine fingerprint. An established adenosine fingerprint includes assessing the blood concentration of one or more adenosine machinery proteins, assessing the enzymatic activity of one or more adenosine machinery proteins, and/or assessing the tumor expression level of adenosine machinery proteins. The methods disclosed herein include administering to said subjects a therapeutic agent selected from the group consisting of an agent targeting the extracellular production of adenosine, and an agent antagonizing the activation by adenosine of one of its receptors.

US Patent:

20190167659, Jun 6, 2019

Filed:

Oct 3, 2018

Appl. No.:

16/150796

Inventors:

- Mountain View CA, US
Dean R. DRAGOLI - Los Altos CA, US
Jaroslaw KALISIAK - Mountain View CA, US
Christopher W. LANGE - El Cerrito CA, US
Manmohan Reddy LELETI - Dublin CA, US
Yandong LI - San Diego CA, US
Rebecca M. LUI - Santa Clara CA, US
Venkat Reddy MALI - Cupertino CA, US
Viengkham MALATHONG - Mountain View CA, US
Jay P. POWERS - Pacifica CA, US
Hiroko TANAKA - Mountain View CA, US
Joanne TAN - San Francisco CA, US
Matthew J. WALTERS - Pacifica CA, US
Ju YANG - Palo Alto CA, US
Penglie ZHANG - Foster City CA, US

International Classification:

A61K 31/47
A61K 31/4709
C07D 405/14
C07D 215/48
C07D 405/04

Abstract:

Compounds of formula (I) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6:

US Patent:

20180092902, Apr 5, 2018

Filed:

Sep 19, 2017

Appl. No.:

15/709012

Inventors:

- Mountain View CA, US
Dean R. DRAGOLI - Los Altos CA, US
Jaroslaw KALISIAK - Mountain View CA, US
Christopher W. LANGE - El Cerrito CA, US
Manmohan Reddy LELETI - West San Jose CA, US
Yandong LI - San Diego CA, US
Rebecca M. LUI - Santa Clara CA, US
Venkat Reddy MALI - Cupertino CA, US
Viengkham MALATHONG - Mountain View CA, US
Jay P. POWERS - Pacifica CA, US
Hiroko TANAKA - Mountain View CA, US
Joanne TAN - San Francisco CA, US
Matthew J. WALTERS - Pacifica CA, US
Ju YANG - Palo Alto CA, US
Penglie ZHANG - Foster City CA, US

International Classification:

A61K 31/47
A61K 31/4709
C07D 215/48
C07D 405/04
C07D 405/14

Abstract:

Compounds of formula (I) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6:

US Patent:

20160296508, Oct 13, 2016

Filed:

Mar 18, 2016

Appl. No.:

15/074965

Inventors:

- Mountain View CA, US
Dean R. Dragoli - Los Altos CA, US
Jarek Kalisiak - Mountain View CA, US
Christopher W. Lange - El Cerrito CA, US
Manmohan Reddy Leleti - Sunnyvale CA, US
Yandong Li - San Diego CA, US
Rebecca M. Lui - Santa Clara CA, US
Venkat Reddy Mali - Cupertino CA, US
Viengkham Malathong - Belmont CA, US
Jay P. Powers - Pacifica CA, US
Hiroko Tanaka - Foster City CA, US
Joanne Tan - San Francisco CA, US
Matthew J. Walters - Pacifica CA, US
Ju Yang - Palo Alto CA, US
Penglie Zhang - Foster City CA, US

International Classification:

A61K 31/47
A61K 31/4709

Abstract:

Compounds of formula (I) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6:

US Patent:

20150175547, Jun 25, 2015

Filed:

Dec 2, 2014

Appl. No.:

14/557949

Inventors:

- Mountain View CA, US
Dean R. Dragoli - Los Altos CA, US
Jarek Kalisiak - Mountain View CA, US
Christopher W. Lange - El Cerrito CA, US
Manmohan Reddy Leleti - Sunnyvale CA, US
Yandong Li - San Diego CA, US
Rebecca M. Lui - Santa Clara CA, US
Venkat Reddy Mali - Cupertino CA, US
Viengkham Malathong - Belmont CA, US
Jay P. Powers - Pacifica CA, US
Hiroko Tanaka - Foster City CA, US
Joanne Tan - San Francisco CA, US
Matthew J. Walters - Pacifica CA, US
Ju Yang - Palo Alto CA, US
Penglie Zhang - Foster City CA, US

International Classification:

C07D 215/48
C07D 405/14
C07D 405/04

Abstract:

Compounds of formula (I) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6: