Matthew Weiss

US Patent:

20130338177, Dec 19, 2013

Filed:

Nov 18, 2011

Appl. No.:

13/988745

Inventors:

Ana Elena Minatti - Santa Monica CA, US
Oleg Epstein - Belmont MA, US
Ryan White - Somerville MA, US
Matthew Weiss - Boston MA, US
Wenge Zhong - Thousand Oaks CA, US
Jonathan D. Low - Tarzana CA, US

Assignee:

AMGEN INC. - Thousand Oaks CA

International Classification:

C07D 491/107
C07D 491/20

US Classification:

514272, 544333, 514256, 546 15, 514278, 544231, 514275, 5483011, 514389

Abstract:

The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula (I), wherein variables A, A, A, A, A, A, L, R, R, R, W and Y of Formula (I) are defined herein. The invention also provides pharmaceutical compositions comprising the compounds, and corresponding uses of the compounds and compositions for treatment of disorders and/or conditions related to plaque formation and deposition, resulting from the activity of BACE. Such BACE mediated disorders include, for example, Alzheimer's Disease, cognitive deficits, cognitive impairments, schizophrenia and other central nervous system conditions. The invention further provides compounds of Formulas (II) and (III), sub-Formula embodiments of Formulas (I), (II) and (III), intermediates and processes and methods useful for the preparation of compounds of Formulae (I-III).

US Patent:

20220358816, Nov 10, 2022

Filed:

Jul 21, 2022

Appl. No.:

17/870048

Inventors:

Matthew Weiss - New York NY, US

International Classification:

G07F 17/32

Abstract:

A method for playing a cooperative card wagering game for a plurality of players and a dealer using a customer cooperative wagering table and a deck of cards with each card having a numerical value, the cooperative wagering table having a dealer table edge, a community table edge, and a community line positioned therebetween, each player has an individual hand, and contributes a card to form a community hand by placing the card upon the community line, the players cooperate to maximize the value of the community hand, while also maximizing their respective individual hands, whereby the players cannot obtain a player win result if the community hand is less than the dealer's hand in value.

US Patent:

20210358274, Nov 18, 2021

Filed:

Jul 27, 2021

Appl. No.:

17/386102

Inventors:

Matthew Weiss - New York NY, US

International Classification:

G07F 17/32

Abstract:

A method for playing a dual-hand card wagering game with a player and a dealer using a wagering table and a deck of cards with each card having a numerical value, the player is dealt cards to form a primary hand, and transfers a card from the primary hand to form a secondary hand, while the dealer retains cards to form a dealer hand. The total numerical values of the primary hand and the secondary hand are compared to the dealer hand to determine a primary result and a secondary result corresponding to a primary or secondary loss, tie, or win. The primary and secondary results are considered in combination to determine a game result corresponding to a player win, player push, or player loss. The dual-hand card wagering game may also be played electronically using a dual-hand card game system.

US Patent:

20210335102, Oct 28, 2021

Filed:

Mar 11, 2021

Appl. No.:

17/198571

Inventors:

Matthew Weiss - Secaucus NJ, US

International Classification:

G07F 17/32

Abstract:

A method for playing a cooperative card wagering game for a plurality of players and a dealer using a customer cooperative wagering table and a deck of cards with each card having a numerical value, the cooperative wagering table having a dealer table edge, a community table edge, and a community line positioned therebetween, each player has an individual hand, and contributes a card to form a community hand by placing the card upon the community line, the players cooperate to maximize the value of the community hand, while also maximizing their respective individual hands, whereby the players cannot obtain a player win result if the community hand is less than the dealer's hand in value.