Mayra Senices from 3 Wildwood Dr, Peabody, MA 01960, age 50, Phone: (978)5366939

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Treating Immunological Disorders Using Agonists Of Interleukin-21 / Interleukin-21 Receptor
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US Patent:

20060159655, Jul 20, 2006
Filed:

Mar 22, 2004
Appl. No.:

10/806611
Inventors:

Mary Collins - Natick MA, US
Elaine Chin - Concord MA, US
Mayra Senices - Peabody MA, US
Deborah Young - Melrose MA, US
Assignee:

Wyeth - Madison NJ
International Classification:

A61K 38/21
A61K 39/395
A61K 31/525
A61K 31/4745
A61K 38/20
US Classification:

424085200, 424143100, 424085500, 424085600, 424085700, 514291000, 514251000
Abstract:

Methods and compositions for modulating interleukin-21 (IL-21)/IL-21 receptor (MU-1) activity using agonists of IL-21 or IL-21 receptor (“IL-21R” or “MU-1”), are disclosed. IL-21/IL-21R agonists can be used by themselves or in combination with anti-inflammatory agents to treat, e.g., ameliorate, symptoms associated with immunological disorders of the nervous system, e.g., multiple sclerosis.