- Washington DC, US - Philadelphia PA, US HANNAH ZLOTNICK - Philadelphia PA, US MEGAN FARRELL - Philadelphia PA, US LIANE MILLER - Philadelphia PA, US DAVID STEINBERG - Philadelphia PA, US
A method for forming a prosthesis comprising a bone-like portion and a cartilage-like portion can comprise additively manufacturing a first positive mold in accordance with a portion of a first three-dimensional model of a portion of a bone. A first negative mold can be formed from the first positive mold. The bone-like portion can be created within the first negative mold. A second positive mold of the bone and a cartilage can be additively manufactured from a second three-dimensional model. A portion of the second three-dimensional model can correspond to a portion of the first three-dimensional model. A second negative mold can be formed from the second positive mold. The bone-like portion can be positioned in the second negative mold so that the second negative mold and the bone-like portion can define a cartilage space that can be filled with a material to form the cartilage-like portion of the prosthesis.
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Melissa Detter, Gerald Knapp, Donald Franks, Sandra Day, Bill Giesler, Marjorie Mattison, Wayne Olson, Richard Tatham, Colene Mattison, Geraldine Hollander
study was led by Dan Huh, Wilf Family Term Assistant Professor in Bioengineering in Penn's School of Engineering and Applied Science, and Cassidy Blundell, a graduate student in the Huh lab. Other lab members, Yoon-Suk Yi, Lin Ma, Emily Tess, Megan Farrell and Andrei Georgescu, contributed to the study.