Megan Pearl Rothney

US Patent:

20130170728, Jul 4, 2013

Filed:

Feb 27, 2013

Appl. No.:

13/778576

Inventors:

General Electric Company - Schenectady NY, US
Thomas Paul Repoff - Sprakers NY, US
Colin Craig McCulloch - Ballston Lake NY, US
Fiona Mary Ginty - Saratoga Springs NY, US
Megan Pearl Rothney - Madison WI, US
Zhengyu Pang - Clifton Park NY, US

Assignee:

General Electric Company - Schenectady NY

International Classification:

G06F 19/18

US Classification:

382133, 702 19

Abstract:

The invention relates generally to a process of analyzing and visualizing the expression of biomarkers in an individual cell wherein the cell is examined to develop patterns of expression by using a grouping algorithm, and a system to perform and display the analysis.

US Patent:

20140371570, Dec 18, 2014

Filed:

Jun 12, 2013

Appl. No.:

13/915876

Inventors:

- Schenectady NY, US
Xin Wang - Clifton Park NY, US
Tzu-Jen Kao - Watervliet NY, US
Megan Pearl Rothney - Madison WI, US

International Classification:

A61B 5/00
A61B 6/00

US Classification:

600407

Abstract:

Methods for measuring liver fat mass are provided. One method includes acquiring dual-energy two-dimensional (2D) scan information from a dual-energy X-ray scan of a body and generating a dual-energy X-ray image of the body using the 2D scan information. The method further includes identifying a region of interest using the dual-energy X-ray image and determining a subcutaneous fat mass for each of a plurality of sections of the region of interest. The method also includes determining a liver fat mass for the region of interest based on the determined subcutaneous fat mass for each of the plurality of sections.

US Patent:

20140314299, Oct 23, 2014

Filed:

Apr 17, 2013

Appl. No.:

13/865036

Inventors:

- Schenectady NY, US
Jens Rittscher - Niskayuna NY, US
Dirk Padfield - Niskayuna NY, US
Ali Can - Niskayuna NY, US
Zhengyu Pang - Niskayuna NY, US
Musodiq Bello - Niskayuna NY, US
Fiona Ginty - Niskayuna NY, US
Christopher Sevinsky - Watervliet NY, US
Qing Li - Niskayuna NY, US
Megan Rothney - Madison WI, US
Brion Sarachan - Schenectady NY, US

International Classification:

G06K 9/00

US Classification:

382133

Abstract:

Improved systems and methods for the analysis of digital images are provided. More particularly, the present disclosure provides for improved systems and methods for the analysis of digital images of biological tissue samples. Exemplary embodiments provide for: i) segmenting, ii) grouping, and iii) quantifying molecular protein profiles of individual cells in terms of sub cellular compartments (nuclei, membrane, and cytoplasm). The systems and methods of the present disclosure advantageously perform tissue segmentation at the sub-cellular level to facilitate analyzing, grouping and quantifying protein expression profiles of tissue in tissue sections globally and/or locally. Performing local-global tissue analysis and protein quantification advantageously enables correlation of spatial and molecular configuration of cells with molecular information of different types of cancer.