Michael K Chan

US Patent:

7545954, Jun 9, 2009

Filed:

Aug 22, 2005

Appl. No.:

11/208792

Inventors:

Michael Chan - Niskayuna NY, US
Anthony Hoogs - Niskayuna NY, US
John Schmiederer - Ballston Spa NY, US

Assignee:

General Electric Company - Niskayuna NY

International Classification:

G06K 9/00
A63F 13/00

US Classification:

382103, 382170, 382181, 463 4

Abstract:

A system recognizes events. The system includes a sequence of continuous vectors and a sequence of binarized vectors. The sequence of continuous vectors represents spatial-dynamic relationships of objects in a predetermined recognition area. The sequence of binarized vectors is derived from the sequence of continuous vectors by utilizing thresholds for determining binary values for each spatial-dynamic relationship. The sequence of binarized vectors indicates whether an event has occurred.

US Patent:

8598980, Dec 3, 2013

Filed:

Jul 19, 2010

Appl. No.:

12/838964

Inventors:

Scott Charles Evans - Burnt Hills NY, US
Rebecca Brown - Clifton Park NY, US
Michael Tin-Lung Chan - Bedford MA, US
Rahul Bhotika - Schenectady NY, US
Srinivas Chukka - San Jose CA, US
David W. Hagan - Orlando FL, US
Ken R. Turner - Bristow VA, US

Assignee:

Lockheed Martin Corporation - Bethesda MD

International Classification:

G05B 19/00
B60R 25/00

US Classification:

340 552, 340 553, 340 57, 340 58, 340 581, 340 582

Abstract:

Methods and systems for determining whether a particular individual is to be granted, among other things, access to information, access to a particular room or other space, or permission to perform a given act or transaction are disclosed. For example, disclosed is an exemplary method that includes performing multiple biometrics tests on the individual to retrieve multiple biometrics test results, performing at least a first data fusion operation on the multiple biometrics test results to determine an identity result, performing at least one biological state test to determine one or more biological state test results of the individual, and conditionally granting authority to the individual based on the identity result and the one or more biological state results.

US Patent:

20060171571, Aug 3, 2006

Filed:

Aug 17, 2005

Appl. No.:

11/205515

Inventors:

Michael Chan - Niskayuna NY, US
Rebecca Brown - Clifton Park NY, US
Wesley Turner - Rexford NY, US
Timothy Kelliher - Scotia NY, US
Ronald Sutton - Orlando FL, US
Mark Cavanagh - Orlando FL, US

International Classification:

G06K 9/00

US Classification:

382115000

Abstract:

An authentication system incorporates pluralilty of fused biometric modalities which are combined with quality indicia of the biometric samples. Fusion processing maps individual modality data along with one or more quality measurements to a fused score for purposes of making an authentication decision.

US Patent:

20090324551, Dec 31, 2009

Filed:

Aug 21, 2006

Appl. No.:

12/064529

Inventors:

Dennis A. Carson - La Jolla CA, US
Kenji Takabayshi - Poway CA, US
Suzanne Grimshaw - Poway CA, US
Howard B. Cottam - Escondido CA, US
Michael Chan - San Diego CA, US
Christina C.N. Wu - Escondido CA, US

Assignee:

The Regents of The University of California Office of Technology Transfer - Oakland CA

International Classification:

A61K 45/00
C07D 473/00
A61K 31/522
C12N 1/20
C12N 7/00
A61P 35/00

US Classification:

424 934, 544276, 51426337, 4352525, 4352521, 4352528, 4352351, 424 935, 424 936

Abstract:

The present invention provides for TLR agonist conjugates (compounds) and compositions, as well as methods of using them. The compounds of the invention are broad-spectrum, long-lasting, and non-toxic combination of synthetic immunostimulatory agents, which are useful for activating the immune system of a mammal, preferably a human and can help direct the pharmacophore to the receptor within the endosomes of target cells and enhance the signal transduction induced by the pharmacophore.

US Patent:

20100210598, Aug 19, 2010

Filed:

Feb 11, 2010

Appl. No.:

12/704343

Inventors:

Dennis A. Carson - La Jolla CA, US
Howard B. Cottam - Escondido CA, US
Tomoko Hayashi - San Diego CA, US
Michael Chan - San Diego CA, US

Assignee:

Regents of the University of California, San Diego - La Jolla CA

International Classification:

A61K 31/522
C07D 473/04
C07F 9/6558
A61K 31/688
C07F 9/6524
A61K 31/685
A61K 31/52
A61P 29/00
A61P 37/06

US Classification:

514 81, 544270, 5142632, 544244, 544269, 51426322, 544271, 5142631

Abstract:

Provided herein are small molecule conjugates that are agonists or antagonists of one or more toll-like receptors.

US Patent:

20130165455, Jun 27, 2013

Filed:

Nov 20, 2012

Appl. No.:

13/682208

Inventors:

Dennis A. Carson - La Jolla CA, US
Howard B. Cottam - Escondido CA, US
Michael Chan - San Diego CA, US
Christina C.N. Wu - Escondido CA, US
Suzanne Grimshaw - Poway CA, US

Assignee:

The Regents of The University of California - Oakland CA

International Classification:

C07D 473/34

US Classification:

5142632, 544276, 51426337

Abstract:

The present invention provides for TLR agonist conjugates (compounds) and compositions, as well as methods of using them. The compounds of the invention are broad-spectrum, long-lasting, and non-toxic combination of synthetic immunostimulatory agents, which are useful for activating the immune system of a mammal, preferably a human and can help direct the pharmacophore to the receptor within the endosomes of target cells and enhance the signal transduction induced by the pharmacophore.

US Patent:

20130202629, Aug 8, 2013

Filed:

Apr 29, 2011

Appl. No.:

13/695385

Inventors:

Dennis A. Carson - La Jolla CA, US
Howard B. Cottam - Escondido CA, US
Tomoko Hayashi - San Diego CA, US
Michael Chan - San Diego CA, US
Christina C.N. Wu - Escondido CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61K 39/39
C07F 9/6561

US Classification:

4241841

Abstract:

The invention provides uses for phospholipid conjugates of TLR agonists, for instance in vaccines, and to prevent, inhibit or treat a variety of disorders including inflammation, cancer and pathogen, e.g., microbe, infection.

US Patent:

20220305121, Sep 29, 2022

Filed:

Aug 15, 2020

Appl. No.:

17/635983

Inventors:

- Oakland CA, US
Tomoko Hayashi - San Diego CA, US
Maripat Corr - San Diego CA, US
Howard B. Cottam - Escondido CA, US
Nijunj Shukla - San Diego CA, US
Michael Chan - San Diego CA, US

International Classification:

A61K 39/39
C12N 7/00
A61K 31/63

Abstract:

Bis-aryl sulfonamide compounds and methods of using those compounds, e.g., in a method of enhancing or prolonging an immune response, are provided. For example, the compounds may be employed with a vaccine and optionally at least one other adjuvant and/or one or more TLR ligands, at least one MAP kinase inhibitor, or any combination thereof.