Michael J Haass

US Patent:

6983176, Jan 3, 2006

Filed:

Apr 11, 2001

Appl. No.:

09/832608

Inventors:

Craig Gardner - Brookline MA, US
Michael J. Haass - Albuquerque NM, US
Robert K. Rowe - Corrales NM, US
Howland Jones - Edgewood NM, US
Steven T. Strohl - Cedar Crest NM, US
Matthew J. Novak - Tucson AZ, US
Russell E. Abbink - Albuquerque NM, US
David Nuñez - Sandia Park NM, US
William Gruner - Edgewood NM, US
Robert D. Johnson - Albuquerque NM, US

Assignee:

Rio Grande Medical Technologies, Inc. - Albuquerque NM

International Classification:

A61B 5/00

US Classification:

600310, 600473, 600476

Abstract:

Systems and methods for establishing and/or maintaining the prediction capability over time of a multivariate calibration model designed for quantitative optical spectroscopic measurement of attributes or analytes in bodily tissues, bodily fluids or other biological samples, which are particularly useful when the spectral absorbance of the attribute or analyte is small relative to the background. The present invention provides an optically similar reference sample to capture the characteristics of instrument and environmental variation and to reduce the effect of such variation on the measurement capability of the model. The optically similar reference is preferably stable over time and is designed such that its optical properties are sufficiently matched to the sample of interest that instrument and environmental variations are captured in the same manner in both the test sample of interest and the optically similar reference sample. The optically similar reference sample may include one or more physical components which are spectroscopically measured in a manner which closely mimics the spectroscopic measurement of the test sample of interest. Spectral similarity may also be achieved by using alternative components with spectral characteristics similar to the components contained in the test sample of interest.

US Patent:

7889349, Feb 15, 2011

Filed:

Nov 16, 2006

Appl. No.:

11/560362

Inventors:

Trent Ridder - Woodbridge VA, US
Ben ver Steeg - Redlands CA, US
Michael Haass - Albuquerque NM, US
John D. Maynard - Albuquerque NM, US
Zachary Benz - Albuquerque NM, US

Assignee:

TruTouch Technologies, Inc. - Albuquerque NM

International Classification:

G01B 9/02
G01J 3/45

US Classification:

356451

Abstract:

The present invention provides improved methods and apparatuses for accurate measurements using interferometers. A functional relationship between the optical path difference and time is determined from a reference signal from an interferometer. The times at which the interferometer had specific optical path differences can be determined from the functional relationship. Those times can then be used to select times at which the spectroscopic signal from the interferometer was produced at the specific optical path differences. The invention can be applied, as examples, to maintain instrument calibration, and to transfer or compare calibrations or measurements across different interferometers.

US Patent:

20040033618, Feb 19, 2004

Filed:

Aug 16, 2002

Appl. No.:

10/222721

Inventors:

Michael Haass - Albuquerque NM, US
Robert Rowe - Corrales NM, US
Edward Thomas - Albuquerque NM, US

International Classification:

G01N021/62

US Classification:

436/171000, 436/008000, 436/164000, 435/014000, 702/019000, 422/082050, 356/051000, 356/300000

Abstract:

A method and apparatus for measuring a biological attribute, such as the concentration of an analyte, particularly a blood analyte in tissue such as glucose. The method utilizes spectrographic techniques in conjunction with an improved instrument-tailored or subject-tailored calibration model. In a calibration phase, calibration model data is modified to reduce or eliminate instrument-specific attributes, resulting in a calibration data set modeling intra-instrument or intra-subject variation. In a prediction phase, the prediction process is tailored for each target instrument separately using a minimal number of spectral measurements from each instrument or subject.

US Patent:

20060239547, Oct 26, 2006

Filed:

Apr 19, 2006

Appl. No.:

11/407179

Inventors:

M. Robinson - Carlsbad CA, US
Russell Abbink - Sandia Park NM, US
Michael Haass - Albuquerque NM, US

International Classification:

G06K 9/00
G06K 9/46

US Classification:

382162000, 382118000, 382190000

Abstract:

The present invention relates to the use of optical skin measurements to determine skin properties such as surface topography, hydration, elasticity, pigmentation intensity or uniformity, dermal thickness, dermal perfusion, presence or concentration or composition of oil on or near the surface, and apparent age of the skin. An apparatus according to the present invention can comprise a skin positioning system for positioning the skin relative to other parts of the apparatus. An illumination system, adapted to produce illumination radiation, can mount with the skin positioning system such that illumination radiation impinges on a first portion of the skin at a first determined angle thereto. A detection system can mount with the skin positioning system such that radiation from a second portion of the skin at a second determined angle therefrom impinges on the detector. An analysis system can receive information from the detection system, and determine one or more skin properties from the detected radiation and the illumination radiation.

US Patent:

20090018415, Jan 15, 2009

Filed:

Sep 26, 2008

Appl. No.:

12/239601

Inventors:

M. Ries Robinson - Albuquerque NM, US
Russell E. Abbink - Sandia Park NM, US
Michael H. Haass - Albuquerque NM, US

International Classification:

A61B 5/00

US Classification:

600310

Abstract:

The present invention provides methods and apparatuses for accurate noninvasive determination of tissue properties. Some embodiments of the present invention comprise an optical sampler having an illumination subsystem, adapted to communicate light having a first polarization along a first path to a tissue surface; a collection subsystem, adapted to collect light having a second polarization communicated from the tissue along a second path after interaction with the tissue; wherein the first polarization is different from the second polarization; and wherein the first path and the second path are substantially parallel for at least of portion of each path.

US Patent:

20100113899, May 6, 2010

Filed:

Nov 6, 2009

Appl. No.:

12/614056

Inventors:

Mark Ries Robinson - Albuquerque NM, US
Andrea Magee - Albuquerque NM, US
Michael U. Haass - Albuquerque NM, US
Russell E. Abbink - Sandia Park NM, US
William Radigan - Albuquerque NM, US
V. Gerald Grafe - Corrales NM, US

International Classification:

A61B 5/1455

US Classification:

600310

Abstract:

This invention relates to measurements of material properties by determination of the response of a sample to incident radiation, and more specifically to the measurement of analytes such as glucose or alcohol in human tissue. Some example embodiments of the present invention provide an optical sampling apparatus including an optical subsystem, having a receiver for receiving light expressed from tissue; and an alignment subsystem, adapted to urge a portion of a hand placed in operative relationship with the alignment subsystem into a defined configuration relative to the receiver. In some such example embodiments, the alignment subsystem includes a substrate having a plurality of projections therefrom disposed in a pattern such that the projections urge a portion of a hand placed on the substrate to a defined configuration relative to the receiver. In some such example embodiments, the alignment subsystem includes a substrate having a surface defining a volume approximating the shape of a portion of a hand such that the volume urges a portion of a hand placed therein to a defined configuration relative to the receiver. In some such example embodiments, the alignment subsystem includes a surface having a generally U-shaped cross-section and extending for a distance, wherein the surface is mounted relative to the sampling means such that a finger placed in the U-shaped cross-section of the surface is urged to a defined configuration relative to the receiver. In some such sample embodiments, the alignment subsystem is customized to portion of the hand of a specific individual.

US Patent:

20100160747, Jun 24, 2010

Filed:

Dec 13, 2009

Appl. No.:

12/636771

Inventors:

Mark Ries Robinson - Albuquerque NM, US
Andrea Magee - Albuquerque NM, US
Michael J. Haass - Albuquerque NM, US
Russell E. Abbink - Sandia Park NM, US
William Radigan - Albuquerque NM, US
V. Gerald Grafe - Corrales NM, US

International Classification:

A61B 5/1468
A61B 5/00

US Classification:

600306, 600316

Abstract:

The present invention relates to measurements of material properties by determination of the response of a sample to incident radiation, and more specifically to the measurement of analytes such as glucose or alcohol in human tissue. The invention is particularly useful in connection with noncontact optical sampling of skin. Some example embodiments of the invention provide for selection of preferred sampling locations responsive to optically-determined characteristics of the tissue. Some example embodiments of the invention provide for precise and repeatable alignment of the tissue based on optically-determined characteristics of the tissue.

US Patent:

6441388, Aug 27, 2002

Filed:

May 3, 2000

Appl. No.:

09/563865

Inventors:

Edward V. Thomas - Albuquerque NM
Robert K. Rowe - Corrales NM
Michael J. Haass - Albuquerque NM

Assignee:

Rio Grande Medical Technologies, Inc. - Albuquerque NM
Sandia Corporation - Albuquerque NM

International Classification:

G01N 1506

US Classification:

250573, 25033909

Abstract:

A method and apparatus for measuring a biological attribute, such as the concentration of an analyte, particularly a blood analyte in tissue such as glucose. The method utilizes spectrographic techniques in conjunction with an improved instrument-tailored calibration model. In a calibration phase, calibration model data is modified to reduce or eliminate instrument-specific attributes, resulting in a calibration data set modeling intra-instrument variation. In a prediction phase, the prediction process is tailored for each target instrument separately using a minimal number of spectral measurements from each instrument.