Michael Robert Hoy

US Patent:

6387411, May 14, 2002

Filed:

Apr 4, 2001

Appl. No.:

09/826072

Inventors:

Richard D. Bruce - Rydal PA
Brid Burruano - King of Prussia PA
Michael R. Hoy - Sellersville PA
Nicholas R. Paquette - Danbury CT

Assignee:

McNeil-PPC, Inc. - Skillman NJ

International Classification:

A61K 914

US Classification:

424489, 424464, 424465, 5147723, 5147724, 514784, 514785, 514786, 514951

Abstract:

A method for preparing sterol/stanol and sterol/stanol ester compositions with improved dispersibility is provided by co-melting the sterol/stanol and/or sterol/stanol ester with highly branched hydrocarbons and then grinding the resulting product. A method for preparing the compounds is also disclosed. The ground compound is suitable for formulating into orally administered products suitable for control of blood serum cholesterol.

US Patent:

55995772, Feb 4, 1997

Filed:

May 31, 1995

Appl. No.:

8/455427

Inventors:

Charles A. Stevens - Lansdale PA
Michael R. Hoy - North Wales PA
Edward J. Roche - Paoli PA

Assignee:

McNeil-PPC, Inc. - Skillman NJ

International Classification:

B05D 312
A61K 924
A61J 300

US Classification:

427 214

Abstract:

A method of making solid oral dosage form for the treatment of gastrointestinal disorders comprising a therapeutically effective amount of a pharmaceutical suitable for the treatment of gastric disorders selected from the group consisting of cimetidine, ranitidine, famotidine, diphenoxylate, loperamide, loperamide-N-oxide, pharmaceutically acceptable salts thereof and combinations thereof; and a therapeutically effective amount of simethicone wherein the pharmaceutical and simethicone are separated by a barrier. The barrier is formed by coating with a polymer impermeable to simethicone.

US Patent:

59194812, Jul 6, 1999

Filed:

Jun 28, 1996

Appl. No.:

8/671991

Inventors:

Sharon L. Cody - Erie PA
Brid T. Devlin - Conshohocken PA
John Dubek - Philadelphia PA
Michael R. Hoy - Sellersville PA

Assignee:

NcNeil-PPC, Inc. - Skillman NJ

International Classification:

A61K 948

US Classification:

424452

Abstract:

The present invention relates to a substantially translucent, semi-solid fill material for a soft gelatin capsule containing a therapeutically effective amount of a pharmaceutical dissolved or suspended in the semi-solid. The semi-solid is sufficiently viscous so that it cannot be readily expelled at room temperature from the capsule with a syringe.

US Patent:

60249803, Feb 15, 2000

Filed:

Jun 28, 1996

Appl. No.:

8/671979

Inventors:

Michael R. Hoy - Sellersville PA

Assignee:

McNeil-PPC, Inc. - Skillman NJ

International Classification:

A61K 948

US Classification:

424456

Abstract:

The present invention relates to a dosage form containing a common enclosure of polymeric material. The enclosure contains multiple phases of semi-solid fill materials containing active ingredients.

US Patent:

54894360, Feb 6, 1996

Filed:

Dec 13, 1993

Appl. No.:

8/166111

Inventors:

Michael R. Hoy - Sellersville PA
Edward J. Roche - Paoli PA

Assignee:

McNeil-PPC, Inc. - Milltown NJ

International Classification:

A61K 920

US Classification:

424441

Abstract:

Chewable tablets are made from a coated medicament wherein the coating comprises a mixture of dimethylaminoethyl methacrylate and neutral methacrylic acid ester and a cellulose ester, e. g. cellulose acetate, cellulose acetate butyrate, cellulose triacetate or a combination thereof and optionally polyvinyl pyrrolidone, and a process for making such tablets and a method of providing taste masking and sustained releasing of medicaments utilizing such coatings.

US Patent:

56793766, Oct 21, 1997

Filed:

May 31, 1995

Appl. No.:

8/455443

Inventors:

Charles A. Stevens - Lansdale PA
Michael R. Hoy - North Wales PA
Edward J. Roche - Paoli PA

Assignee:

McNeil-PPC, Inc. - Skillman NJ

International Classification:

A61K 924
A61K 926
A61K 952

US Classification:

424472

Abstract:

A solid oral dosage form for the treatment of gastrointestinal disorders comprising a therapeutically effective amount of a pharmaceutical suitable for the treatment of gastric disorders selected from the group consisting of cimetidine, ranitidine, famotidine, diphenoxylate, loperamide, loperamide-N-oxide, pharmaceutically acceptable salts thereof and combinations thereof; and a therapeutically effective amount of simethicone wherein the pharmaceutical and simethicone are separated by a barrier which is substantially impermeable to simethicone.

US Patent:

56608594, Aug 26, 1997

Filed:

Dec 29, 1994

Appl. No.:

8/366271

Inventors:

Sharon L. Cody - Philadelphia PA
Michael R. Hoy - Sellersville PA
Eric J. Walter - Philadelphia PA

Assignee:

McNeil-PPC, Inc. - Skillman NJ

International Classification:

A61K 948
A61K 964

US Classification:

424451

Abstract:

The present invention relates to gelling liquid polyethylene glycol at room temperature with calcium acetate.

US Patent:

6054144, Apr 25, 2000

Filed:

Nov 4, 1998

Appl. No.:

9/185788

Inventors:

Brid Burruano - King of Prussia PA
Richard D. Bruce - Rydal PA
Michael R. Hoy - Sellersville PA
John D. Higgins - Ft. Washington PA

Assignee:

McNeil-PPC, Inc. - Skillman NJ

International Classification:

A61K 920

US Classification:

424464

Abstract:

A method for preparing. beta. -sitosterol, oryzanol, esters of both of these compounds and related compounds are disclosed which provides the sterol in a readily consumable form. The method includes the spray drying of the. beta. -sitosterol in a mixed micelle formulation. The product is provided in a convenient form that can be provided to food or drinks or incorporated into solid and suspension dosage forms.