Michael S Huston

US Patent:

20220260525, Aug 18, 2022

Filed:

Dec 23, 2021

Appl. No.:

17/560837

Inventors:

- San Jose CA, US
Kelly GARDNER - Berkeley CA, US
Danh C. TRAN - Hayward CA, US
Eric JABART - Berkeley CA, US
David NILSON - Walnut Creek CA, US
Yuri KOUCHNIR - Sunnyvale CA, US
Michael HUSTON - San Jose CA, US
Colin B. KENNEDY - Greenbrae CA, US
David John ROACH - Los Gatos CA, US

Assignee:

ProteinSimple - San Jose CA

International Classification:

G01N 27/447

Abstract:

A system for assaying a biological sample for a presence of a target analyte includes an assaying device and a computer controller. The assaying device includes a housing, a receptacle disposed in the housing, and a source of activation energy. The receptacle is configured to accept an electrophoresis cell. The electrophoresis cell has a recess area configured to accept a chip configured to accept the biological sample. The chip includes a polymeric separation medium with activatable functional groups that covalently bond to the target analyte when activated. The source of activation energy is configured to supply activation energy to activate the activatable functional groups. The computer controller is operably coupled to the source of activation energy and is configured to activate the source of activation energy to direct an application of activation energy to the polymeric separation medium to activate the activatable functional groups.

US Patent:

20160370319, Dec 22, 2016

Filed:

May 20, 2016

Appl. No.:

15/160636

Inventors:

- Santa Clara CA, US
Kelly Gardner - Berkeley CA, US
Danh C. Tran - Hayward CA, US
Eric Jabart - Berkeley CA, US
David Nilson - Walnut Creek CA, US
Yuri Kouchnir - Sunnyvale CA, US
Michael Huston - San Jose CA, US
Colin B. Kennedy - Greenbrae CA, US
David John Roach - Los Gatos CA, US

International Classification:

G01N 27/447

Abstract:

A system for assaying a biological sample for a presence of a target analyte includes an assaying device and a computer controller. The assaying device includes a housing, a receptacle disposed in the housing, and a source of activation energy. The receptacle is configured to accept an electrophoresis cell. The electrophoresis cell has a recess area configured to accept a chip configured to accept the biological sample. The chip includes a polymeric separation medium with activatable functional groups that covalently bond to the target analyte when activated. The source of activation energy is configured to supply activation energy to activate the activatable functional groups. The computer controller is operably coupled to the source of activation energy and is configured to activate the source of activation energy to direct an application of activation energy to the polymeric separation medium to activate the activatable functional groups.