Michael W Kaufman

US Patent:

7029821, Apr 18, 2006

Filed:

Feb 11, 2004

Appl. No.:

10/777997

Inventors:

Richard J. Carey - Sherborn MA, US
Peter Trefonas, III - Medway MA, US
Michael J. Kaufman - Holliston MA, US

Assignee:

Rohm and Haas Electronic Materials LLC - Marlborough MA

International Classification:

G03F 7/00
G03F 7/004

US Classification:

4302701, 430326, 430950

Abstract:

Methods are provides methods are provided to prepare photoresist and organic antireflective coating composition with a filter having a mean pore size of less than about 0. 4 microns. Photoresist compositions and antireflective coatings produced by such methods can provide manufactured microelectronic devices that have significantly reduced defects. Photoresist and antireflective compositions obtainable by such methods also are provided.

US Patent:

7498115, Mar 3, 2009

Filed:

Dec 6, 2005

Appl. No.:

11/294816

Inventors:

Joan M. Mintz - Harvard MA, US
Michael J. Kaufman - Holliston MA, US
Norman S. Jessiman - Southborough MA, US

Assignee:

Rohm and Haas Electronic Materials LLC - Marlborough MA

International Classification:

G03C 1/492
G03C 1/494
G03C 1/76

US Classification:

4302701, 430269, 4302811

Abstract:

Photoresists of the invention contain an added acid reaction component together with one or more resins and a photoactive component. Preferred photoresists of the invention can provide processes substrates such as microelectronic wafers with desired iso-dense bias values. Particularly preferred photoresists of the invention are chemically-amplified positive-acting resists and contain an ester-based solvent such as ethyl lactate or propylene glycol methyl ether acetate in addition to the acid reaction component.

US Patent:

20090105908, Apr 23, 2009

Filed:

Oct 20, 2008

Appl. No.:

12/254178

Inventors:

Robert Casey - Saugus MA, US
Michael T. Gansler - Candia NH, US
John B. Morrell - Hamden CT, US
Michael F. Kaufman - New Boston NH, US
Jon M. Stevens - Manchester NH, US

Assignee:

Segway Inc. - Bedford NH

International Classification:

B62D 6/00

US Classification:

701 41

Abstract:

An apparatus and method for controlling a steering command of a vehicle is provided. A deadband value based on a current state of a transporter is applied to a roll compensated steering command to control steering of the vehicle. A gain is applied to a steering command to control steering of the vehicle.

US Patent:

20090325903, Dec 31, 2009

Filed:

Jun 16, 2009

Appl. No.:

12/485344

Inventors:

Eric L. Elliott - Brighton MA, US
Abu J. Ferdous - Winchester MA, US
Michael J. Kaufman - Lexington MA, US
Sonja A. Komar - Belmont MA, US
Debra L. Mazaik - Hopkinton MA, US
Quentin J. McCubbin - Belmont MA, US
Phuong Nguyen - Cambridge MA, US
Vaithianathan Palaniappan - Andover MA, US
Raymond D. Skwierczynski - Andover MA, US
Nobel T. Truong - Milford MA, US
Csanad M. Varga - Cambridge MA, US
Peter N. Zawaneh - Cambridge MA, US

Assignee:

Millennium Pharmaceuticals, Inc. - Cambridge MA

International Classification:

A61K 31/69
C07F 5/04
A61P 35/00

US Classification:

514 64, 558288, 544229

Abstract:

The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.

US Patent:

20130165390, Jun 27, 2013

Filed:

Nov 2, 2012

Appl. No.:

13/667164

Inventors:

Millennium Pharmaceuticals, Inc. - Cambridge MA, US
Abu J. Ferdous - Winchester MA, US
Michael J. Kaufman - Lexington MA, US
Sonja A. Komar - Belmont MA, US
Debra L. Mazaik - Hopkinton MA, US
Quentin J. McCubbin - Belmont MA, US
Phuong M. Nguyen - Cambridge MA, US
Vaithianathan Palaniappan - Andover MA, US
Raymond D. Skwierczynski - Andover MA, US
Nobel T. Truong - Milford MA, US
Csanad M. Varga - Cambridge MA, US
Peter N. Zawaneh - Cambridge MA, US

Assignee:

MILLENNIUM PHARMACEUTICALS, INC. - Cambridge MA

International Classification:

C07K 5/06

US Classification:

514 193, 558288, 544229, 546 13

Abstract:

The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.

US Patent:

20220370423, Nov 24, 2022

Filed:

Jun 21, 2022

Appl. No.:

17/845275

Inventors:

- Waltham MA, US
Michael D. Kaufman - Waltham MA, US
Oliver Rosen - Waltham MA, US
Bryan D. Smith - Waltham MA, US

International Classification:

A61K 31/4375
A61P 35/04
A61K 31/495

Abstract:

The present disclosure relates to the use of 1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea or 1-(5-(7-amino-1-ethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-bromo-2-fluorophenyl)-3-phenylurea in the treatment of cancers. Specifically, the disclosure is directed to methods of inhibiting PDGFR kinases and treating cancers and disorders associated with inhibition of PDGFR kinases including lung adenocarcinoma, squamous cell lung cancer, glioblastoma, pediatric glioma, astrocytomas, sarcomas, gastrointestinal stromal tumors, malignant peripheral nerve sheath sarcoma, intimal sarcomas, hypereosinophilic syndrome, idiopathic hypereosinophilic syndrome, chronic eosinophilic leukemia, eosinophilia-associated acute myeloid leukemia, or lymphoblastic T-cell lymphoma.

US Patent:

20220370424, Nov 24, 2022

Filed:

Jun 21, 2022

Appl. No.:

17/845278

Inventors:

- Waltham MA, US
Michael D. Kaufman - Waltham MA, US
Oliver Rosen - Waltham MA, US
Bryan D. Smith - Waltham MA, US

International Classification:

A61K 31/4375
A61P 35/04
A61K 31/495

Abstract:

The present disclosure relates to the use of 1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea or 1-(5-(7-amino-1-ethyl-2-oxo-1,2-dihydro-1, 6-naphthyridin-3-yl)-4-bromo-2-fluorophenyl)-3-phenylurea in the treatment of cancers. Specifically, the disclosure is directed to methods of inhibiting PDGFR kinases and treating cancers and disorders associated with inhibition of PDGFR kinases including lung adenocarcinoma, squamous cell lung cancer, glioblastoma, pediatric glioma, astrocytomas, sarcomas, gastrointestinal stromal tumors, malignant peripheral nerve sheath sarcoma, intimal sarcomas, hypereosinophilic syndrome, idiopathic hypereosinophilic syndrome, chronic eosinophilic leukemia, eosinophilia-associated acute myeloid leukemia, or lymphoblastic T-cell lymphoma.

US Patent:

20160031913, Feb 4, 2016

Filed:

Oct 12, 2015

Appl. No.:

14/880776

Inventors:

- Cambridge MA, US
Abu J. Ferdous - Winchester MA, US
Michael J. Kaufman - Lexington MA, US
Debra L. Mazaik - Holliston MA, US
Quentin J. Mccubbin - Belmont MA, US
Phuong M. Nguyen - Cambridge MA, US
Vaithianathan Palaniappan - Andover MA, US
Raymond D. Skwierczynski - Andover MA, US
Nobel T. Truong - Milford MA, US
Csanad Varga - Newton MA, US
Peter N. Zawaneh - Cambridge MA, US

International Classification:

C07F 5/04

Abstract:

The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.