Michael P Kilgard

US Patent:

7024398, Apr 4, 2006

Filed:

Nov 1, 2001

Appl. No.:

10/000844

Inventors:

Michael Kilgard - Richardson TX, US
Michael M. Merzenich - San Francisco CA, US
Shaowen Bao - San Francisco CA, US

Assignee:

Scientific Learning Corporation - Berkeley CA
The University of Texas - Austin TX
The Regents of the University of California - Oakland CA

International Classification:

G06F 15/18

US Classification:

706 25

Abstract:

The invention described herein provides computer-implemented methods and systems for alleviating an abnormal behavior, such as a behavior associated with a fear, abnormal activity, or obsession. It has been found that behaviorally abnormal self-sustaining behaviors may be unlearned or diminished through directed forms of computer-implemented interaction. The computer-implemented interaction is generally directed to reduce the neurological representations of inputs and actions associated with the abnormal behavior. The interaction will typically comprise strategically and repeatedly presenting computer-implemented stimuli including context related to the abnormal behavior. The computer-implemented stimuli are then repeatedly presented and altered over time in a manner that alleviates the abnormal behavior. For example, the content of the computer-implemented stimuli may change to gradually vary in their ability to trigger an episode in the person. In this manner, the neurological representation pertaining to the undesirable behavior may be gradually reduced.

US Patent:

8489185, Jul 16, 2013

Filed:

Jun 16, 2009

Appl. No.:

12/485857

Inventors:

Michael Kilgard - Dallas TX, US
Larry Cauller - Plano TX, US
Navzer Engineer - Plano TX, US
Christa McIntyre - Richardson TX, US
Will Rosellini - Dallas TX, US

Assignee:

The Board of Regents, The University of Texas System - Austin TX

International Classification:

A61N 1/00

US Classification:

607 2, 607 1, 607 3, 607 44, 607 45, 607 48, 607 49

Abstract:

Systems, methods and devices for paired training include timing controls so that training and neural stimulation can be provided simultaneously. Paired trainings may include therapies, rehabilitation and performance enhancement training. Stimulations of nerves such as the vagus nerve that affect subcortical regions such as the nucleus basalis, locus coeruleus or amygdala induce plasticity in the brain, enhancing the effects of a variety of therapies, such as those used to treat tinnitus, stroke, traumatic brain injury and post-traumatic stress disorder.

US Patent:

20100003656, Jan 7, 2010

Filed:

Jun 15, 2009

Appl. No.:

12/485040

Inventors:

Michael Kilgard - Richardson TX, US
Larry Cauller - Plano TX, US
Navzer Engineer - Plano TX, US
Christa Mclntyre - Richardson TX, US
Will Rosellini - Dallas TX, US

Assignee:

The Board of Regents, The University of Texas System - Austin TX

International Classification:

G09B 23/28
A61N 1/36

US Classification:

434262, 607 3

Abstract:

Systems, methods and devices for paired training include timing controls so that training and neural stimulation can be provided simultaneously. Paired trainings may include therapies, rehabilitation and performance enhancement training. Stimulations of nerves such as the vagus nerve that affect subcortical regions such as the nucleus basalis, locus coeruleus or amygdala induce plasticity in the brain, enhancing the effects of a variety of therapies, such as those used to treat tinnitus, stroke, traumatic brain injury and post-traumatic stress disorder.

US Patent:

20100004705, Jan 7, 2010

Filed:

Jun 16, 2009

Appl. No.:

12/485860

Inventors:

Michael Kilgard - Dallas TX, US
Larry Cauller - Plano TX, US
Navzer Engineer - Plano TX, US
Christa McIntyre - Richardson TX, US
Will Rosellini - Dallas TX, US

Assignee:

MICROTRANSPONDER INC. - Dallas TX
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM - Austin TX

International Classification:

A61F 11/00
A61N 1/36

US Classification:

607 3

Abstract:

Systems, methods and devices for paired training include timing controls so that training and neural stimulation can be provided simultaneously. Paired trainings may include therapies, rehabilitation and performance enhancement training. Stimulations of nerves such as the vagus nerve that affect subcortical regions such as the nucleus basalis, locus coeruleus or amygdala induce plasticity in the brain, enhancing the effects of a variety of therapies, such as those used to treat tinnitus, stroke, traumatic brain injury and post-traumatic stress disorder.

US Patent:

62219081, Apr 24, 2001

Filed:

Dec 31, 1998

Appl. No.:

9/224510

Inventors:

Michael P. Kilgard - Richardson TX
Michael M. Merzenich - San Francisco CA

Assignee:

Scientific Learning Corporation - Berkeley CA
Regents of the University of California - Oakland CA

International Classification:

A61K 3122
A61K 118

US Classification:

514546

Abstract:

A system for stimulating brain plasticity releases acetylcholine into the learner's brain while the learner is receiving incoming stimuli or performing an activity during the learning process. It is believed that acetylcholine helps the brain in the learning and memorizing process. In one embodiment, the nucleus basalis region of the learner's brain is electrically stimulated to release acetylcholine, thereby aiding the learning and memorizing process. The electrical stimulation advantageously reduces the need for the learner to attach "behavioral importance" and to pay close attention on the incoming stimuli or activity to stimulate the release of acetylcholine. In other embodiments, delivery systems such as microinjection, implanted micro release devices or implanted photo-sensitive release devices may be used to release acetylcholine into the brain to aid the learning process.

US Patent:

20220355111, Nov 10, 2022

Filed:

May 30, 2022

Appl. No.:

17/804576

Inventors:

- Austin TX, US
Michael P. Kilgard - Richardson TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61N 1/36
A61N 1/372
G09B 19/00

Abstract:

Provided is an effective stereognosis training system that integrates hardware and software to provide a simple, reliable, quantitative system to provide tactile rehabilitation and progress monitoring. The system can include an interactive device including a novel set of objects, that are combined with neuromodulatory systems such as wireless closed-loop vagus nerve stimulation to improve neural plasticity and expedite functional recovery. The system can send updates to therapists or clinicians to monitor progress and encourage compliance with prescribed therapy.

US Patent:

20210316141, Oct 14, 2021

Filed:

Apr 15, 2021

Appl. No.:

17/231165

Inventors:

- Austin TX, US
Michael P. KILGARD - Richardson TX, US
Patrick D. GANZER - Richardson TX, US
Seth A. HAYS - Richardson TX, US

International Classification:

A61N 1/36

Abstract:

Provided herein are methods for the treatment of spinal cord injury in a subject by administering vagus nerve stimulation. In particular, the vagus nerve stimulation is administered in combination with conventional rehabilitation training.

US Patent:

20200215329, Jul 9, 2020

Filed:

Nov 12, 2019

Appl. No.:

16/681575

Inventors:

- Austin TX, US
Michael P. Kilgard - Richardson TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61N 1/36
A61N 1/372
G09B 19/00

Abstract:

Provided is an effective stereognosis training system that integrates hardware and software to provide a simple, reliable, quantitative system to provide tactile rehabilitation and progress monitoring. The system can include an interactive device including a novel set of objects, that are combined with neuromodulatory systems such as wireless closed-loop vagus nerve stimulation to improve neural plasticity and expedite functional recovery. The system can send updates to therapists or clinicians to monitor progress and encourage compliance with prescribed therapy.