Jagadish C. Sircar - San Diego CA Mark L. Richards - La Jolla CA Michael G. Campbell - Durham NC Michael W. Major - Glendale WI
Assignee:
Avanir Pharmaceuticals - San Diego CA
International Classification:
A61K 31415
US Classification:
514394
Abstract:
This invention relates to a family of diacyl benzimidazole analogs, which are inhibitors of the IgE response to allergens. These compounds are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic.
Coumarinic Compounds Having Ige Affecting Properties
Jagadish C. Sircar - San Diego CA 92130 Mark L. Richards - La Jolla CA 92037 Michael G. Campbell - Durham NC 27713 Michael W. Major - Glendale WI 53217
International Classification:
A61K 31423
US Classification:
514375, 514394, 548217, 5483051
Abstract:
The present invention is directed to small molecule inhibitors of the IgE response to allergens which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic.
This invention relates to a family of phenylbenzimidazole analogs, which are inhibitors of the IgE response to allergens. These compounds are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic.
Jagadish C. Sircar - San Diego CA, US Mark L. Richards - San Diego CA, US Michael G. Campbell - Durham NC, US Michael W. Major - Mequon WI, US
Assignee:
Avanir Pharmaceuticals - San Diego CA
International Classification:
A61K031/415 A61K031/423 A61K031/4184
US Classification:
514394, 514375, 5483097, 5483101, 5483107
Abstract:
This invention relates to a family of benzimidazole analogs, which are inhibitors of the IgE response to allergens. These compounds are useful in the treatment of allergy, asthma, or any diseases where IgE is pathogenic.
Michael Major - Mequon WI, US Robert Peterson - Germantown WI, US Szymon Kosinski - Menomonee Falls WI, US
Assignee:
Amicus Therapeutics, Inc. - Cranbury NJ
International Classification:
C08B 37/00 C07H 5/04 C07H 5/06
US Classification:
536 553
Abstract:
Novel processes for the purification of an imino or amino sugar, such as D-1-deoxygalactonojirimycin (DGJ). Particularly, there are described processes for the purification of multi-kilogram scale sugars using hydrochloric acid.
This invention relates to a family of benzimidazole analogs, which are inhibitors of the IgE response to allergens. These compounds are useful in the treatment of allergy, asthma, or any diseases where IgE is pathogenic.
Jagadish Sircar - San Diego CA, US Mark Richards - San Diego CA, US Michael Campbell - Durham NC, US Michael Major - Mequon WI, US
International Classification:
A61K031/4184 C07D235/18
US Classification:
514394000, 548310700
Abstract:
This invention relates to a family of phenylbenzimidazole analogs, which are inhibitors of the IgE response to allergens. These compounds are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic.
Crystalline Sugar Compositions And Method Of Making
Michael Major - Mequon WI, US Robert Peterson - Germantown WI, US Daniel Linse - Milwaukee WI, US Szymon Kosinski - Menomonee Falls WI, US Xiaoxiang Zhu - Cranbury NJ, US
International Classification:
A61K 31/7024 C07H 13/02 C07H 5/04
US Classification:
514023000, 536119000, 536018700
Abstract:
Described are novel crystalline pivaloyl furanoses and methods of crystallizing the pivaloyl furanoses. These compounds are useful as intermediates in the synthesis of compounds such as the deoxyjirimycins and nojirimycins and are particularly useful as intermediates for production on a multi-kg scale. Particular crystalline compounds include 1,2,3,6-tetrapivaloyl-α-D-galactofuranose, 1,2,3,6-tetrapivaloyl-α-L-altrofuranose, and 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-α-D-galactofuranose.
Dr. Major graduated from the Dartmouth Medical School in 1994. He works in Moody, ME and specializes in Internal Medicine. Dr. Major is affiliated with York Hospital.
Revere HealthWasatch Ear Nose Throat & Allergy 950 Medical Dr STE 103, Brigham City, UT 84302 (877)8660170 (phone), (801)8660169 (fax)
Revere HealthWasatch Ear Nose Throat & Allergy 5896 S Ridgeline Dr STE B, Ogden, UT 84405 (801)8660170 (phone), (801)8660169 (fax)
Education:
Medical School University of Utah School of Medicine Graduated: 1996
Procedures:
Myringotomy and Tympanotomy Rhinoplasty Sinus Surgery Skull/Facial Bone Fractures and Dislocations Allergen Immunotherapy Allergy Testing Hearing Evaluation Tonsillectomy or Adenoidectomy Tympanoplasty
Dr. Major graduated from the University of Utah School of Medicine in 1996. He works in Ogden, UT and 1 other location and specializes in Otolaryngology and Allergy. Dr. Major is affiliated with Brigham City Community Hospital, Intermountain McKay-Dee Hospital Center and Ogden Regional Medical Center.
Southern Utah Neurosciences Institute 652 S Medical Ctr Dr STE 420, Saint George, UT 84790 (435)2516800 (phone), (435)2516801 (fax)
Education:
Medical School Creighton University School of Medicine Graduated: 1975
Procedures:
Spinal Fusion Spinal Surgery Arthrocentesis Spinal Cord Surgery
Conditions:
Fractures, Dislocations, Derangement, and Sprains Internal Derangement of Knee Cartilage Intervertebral Disc Degeneration Osteoarthritis Osteomyelitis
Languages:
English Spanish
Description:
Dr. Major graduated from the Creighton University School of Medicine in 1975. He works in Saint George, UT and specializes in Orthopaedic Surgery. Dr. Major is affiliated with Dixie Regional Medical Center River Road Campus and Valley View Medical Center.
University Oklahoma Health Center-Anesthesia 750 NE 13 St STE 200, Oklahoma City, OK 73104 (405)2714351 (phone), (405)2718695 (fax)
Education:
Medical School Oklahoma State University Center for Health Sciences College of Osteopathic Medicine Graduated: 1982
Languages:
English
Description:
Dr. Major graduated from the Oklahoma State University Center for Health Sciences College of Osteopathic Medicine in 1982. He works in Oklahoma City, OK and specializes in Anesthesiology. Dr. Major is affiliated with OU Medical Center Edmond and OU Medical Center The Childrens Hospital.