Michael J Marx

US Patent:

43235646, Apr 6, 1982

Filed:

Mar 9, 1978

Appl. No.:

5/884933

Inventors:

John H. Fried - Palo Alto CA
Denis J. Kertesz - Mountain View CA
Michael Marx - Sunnyvale CA

Assignee:

Syntex (U.S.A.) Inc. - Palo Alto CA

International Classification:

A61K 3158
C07J 500

US Classification:

424241

Abstract:

The 17-butyrate, 17-benzoate, 17,21-methyl orthobutyrate, 17,21-methyl orthobenzoate, and 17,21-dibutyrate esters of cloprednol (6-chloro-11. beta. , 17. alpha. , 21-trihydroxy-pregna-1,4,6-triene-3,20-dione) are useful as topical, anti-inflammatory steroids.

US Patent:

42619955, Apr 14, 1981

Filed:

Aug 31, 1979

Appl. No.:

6/071442

Inventors:

Klaus Weinhardt - Redwood City CA
Michael Marx - Sunnyvale CA

Assignee:

Syntex (U.S.A.) Inc. - Palo Alto CA

International Classification:

A61K 31505
C07D23914
C07D23916

US Classification:

424251

Abstract:

Certain 1,4,5,6-tetrahydropyrimidine compounds which are substituted with an amino, amido or carbamate at the 2-position, with an optionally substituted phenyl at the 5-position or at the 4-position when there is no alkyl at the 1-position and optionally a lower alkyl at the 1-position when the phenyl is at the 5-position are useful as CNS agents and as antihypertensives.

US Patent:

40384098, Jul 26, 1977

Filed:

Mar 1, 1976

Appl. No.:

5/662786

Inventors:

Keith A. M. Walker - Palo Alto CA
Michael Marx - Sunnyvale CA

Assignee:

Syntex (U.S.A.) Inc. - Palo Alto CA

International Classification:

A61K 31415
C07D23360

US Classification:

424273

Abstract:

Novel 1-phenethylimidazoles substituted at the position. beta. to the imidazole ring by an optionally substituted hydrocarbyl ester, thioester, or dithioester are useful as antimicrobial agents and as intermediates in the preparation of novel 1-phenethylimidazoles substituted at the position. beta. to the imidazole with a mercapto. Both the former and latter compounds are useful as intermediates in the preparation of certain 1-[. beta. -(R-thio)phenethyl] imidazoles.

US Patent:

40369706, Jul 19, 1977

Filed:

Mar 8, 1976

Appl. No.:

5/664600

Inventors:

Keith A. M. Walker - Palo Alto CA
Michael Marx - Sunnyvale CA

Assignee:

Syntex (U.S.A.) Inc. - Palo Alto CA

International Classification:

A61K 31415
C07D23360

US Classification:

424273

Abstract:

Compounds of the formula ##STR1## wherein R. sup. 1 and R. sup. 2 are independently benzyl substituted benzyl, phenyl or substituted phenyl, said substituted benzyl and substituted phenyl substituted on the phenyl ring with one or more substituents independently selected from the group consisting of halo, lower alkyl and trifluoromethyl; X and Y are independently oxygen or sulfur with the proviso that Y is not oxygen when R. sup. 2 is phenyl or substituted phenyl; and the antimicrobial acid addition salts thereof are useful as antifungal, antibacterial and antiprotozoal agents.

US Patent:

40369730, Jul 19, 1977

Filed:

Mar 8, 1976

Appl. No.:

5/664800

Inventors:

Keith A. M. Walker - Palo Alto CA
Michael Marx - Sunnyvale CA

Assignee:

Syntex (U.S.A.) Inc. - Palo Alto CA

International Classification:

A61K 31415
C07D23360

US Classification:

424273

Abstract:

Compounds of the formula ##STR1## wherein one of R. sup. 1 and R. sup. 2 is alkyl or the group ##STR2## IN WHICH N IS 0 TO 3 AND THE OTHER OF R. sup. 1 and R. sup. 2 is benzyl, substituted benzyl, phenyl or substituted phenyl, said substituted benzyl and substituted phenyl substituted on the phenyl ring with one or more substituents independently selected from the group consisting of halo, lower alkyl and trifluoromethyl; X and Y are independently oxygen or sulfur with the proviso that Y is not oxygen when R. sup. 2 is phenyl or substituted phenyl; and the antimicrobial acid addition salts thereof are useful as antifungal, antibacterial and antiprotozoal agents.

US Patent:

43224210, Mar 30, 1982

Filed:

Dec 1, 1980

Appl. No.:

6/211610

Inventors:

Klaus Weinhardt - Redwood City CA
Michael Marx - Sunnyvale CA

Assignee:

Syntex (U.S.A.) Inc. - Palo Alto CA

International Classification:

A61K 31505

US Classification:

424251

Abstract:

Certain 1,4,5,6-tetrahydropyrimidine compounds which are substituted with an amino, amido or carbamate at the 2-position, with an optionally substituted phenyl at the 5-position or at the 4-position when there is no alkyl at the 1-position and optionally a lower alkyl at the 1-position when the phenyl is at the 5-position are useful as CNS agents and as antihypertensives.

US Patent:

40369749, Jul 19, 1977

Filed:

Mar 8, 1976

Appl. No.:

5/664840

Inventors:

Keith A. M. Walker - Palo Alto CA
Michael Marx - Sunnyvale CA

Assignee:

Syntex (U.S.A.) Inc. - Palo Alto CA

International Classification:

A61K 31415
C07D23360

US Classification:

424273

Abstract:

Compounds of the formula ##STR1## wherein R. sup. 1 and R. sup. 2 are independently alkyl or the group ##STR2## IN WHICH N IS 0 TO 3; X and Y are independently oxygen or sulfur; and the antimicrobial acid addition salts thereof are useful as antifungal, antibacterial and antiprotozoal agents.

US Patent:

20200141716, May 7, 2020

Filed:

Feb 11, 2019

Appl. No.:

16/272258

Inventors:

- Mountain View CA, US
Caner Onal - Palo Alto CA, US
Michael Marx - Mountain View CA, US
Blaise Gassend - East Palo Alto CA, US

International Classification:

G01B 9/02
G01S 17/10
G06K 9/62
G01S 17/89

Abstract:

One example method involves a light detection and ranging (LIDAR) device focusing light from a target region in a scene for receipt by a detector. The method also involves emitting a primary light pulse. The method also involves directing, via one or more optical elements, the primary light pulse toward the target region. The primary light pulse illuminates the target region according to a primary light intensity of the primary light pulse. The method also involves emitting a secondary light pulse. At least a portion of the secondary light pulse illuminates the target region according to a secondary light intensity of the secondary light pulse. The secondary light intensity is less than the primary light intensity.