Michael P Morin

US Patent:

6410275, Jun 25, 2002

Filed:

Oct 18, 1999

Appl. No.:

09/420139

Inventors:

Bryan Kluttz - Norwell MA
Lawrence Burg - Framingham MA
Garry Tegeler - Hazelwood MO
Louis Graziano - Rockland MA
Christopher Cotter - Charlestown MA
Michel Guy - Scituate MA
James Greer - Rockland MA
Geoff McKinley - Duxbury MA
Luigi Catanzariti - Duxbury MA
James Clement Bishop - Columbia MO
Bruno Colin - Marcy lEtoile, FR
Cécile Paris - Lyons, FR
Thomas Wang - Lexington MA
Michael Morin - Dedham MA

Assignee:

bioMerieux, Inc. - Hazelwood MO

International Classification:

C12P 1934

US Classification:

435 911, 435 912, 4352851, 4352872, 4352873, 4352876, 4352885, 422 64, 422101, 422102, 935 78, 935 87, 935 88

Abstract:

A unit dose test device for a nucleic acid amplification reaction has the form of a elongate disposable test strip. The test strip includes a dual-chamber reaction vessel pre-loaded with nucleic acid amplification reaction reagents, and a plurality of wells for processing a reaction occurring in the reaction vessel.

US Patent:

6591469, Jul 15, 2003

Filed:

Sep 13, 2002

Appl. No.:

10/242899

Inventors:

Michael G. Morin - Keene NH

Assignee:

Sonnax Industries, Inc. - Bellows Falls VT

International Classification:

B23P 600

US Classification:

2940208, 29244, 29255, 29256, 29259, 29264, 29271, 294264, 294265, 29724

Abstract:

A special purpose tool for manual installation and removal of bushings or sleeve bearings from press fit bearing housings within automotive engines, transmissions, and other machinery with no resultant damage to the housing is disclosed. The present tool is comprised of a cylindrical body member including a pilot diameter, which aligns the tool in coaxial relation to the bushing and a bushing locating journal that engages the bushing to be removed. A plurality of machine screws are disposed in the body member at predetermined radial positions. To remove a bushing the machine screws are advanced axially within threaded holes such that the machine screw threads tap into and capture the worn bushing and/or bearing sleeve and the tool is withdrawn. The present tool is also utilized to manually install new bushings into housings and other components by removal of the aforementioned machine screws.

US Patent:

7290987, Nov 6, 2007

Filed:

Oct 14, 2004

Appl. No.:

10/966590

Inventors:

Michael G. Morin - Keene NH, US

Assignee:

Sonnax Industries, Inc. - Bellews Falls VT

International Classification:

F16D 33/18

US Classification:

416171, 416174, 416180, 416197 C, 416213 A, 416244 R, 4152161, 415229, 415230, 60330, 60358, 384276

Abstract:

A direct replacement impeller hub for the torque converter of an automatic transmission and a method of repairing an impeller assembly utilizing the replacement impeller hub to provide increased service longevity. In the present impeller hub the geometric roundness characteristic of the impeller hub is controlled to an exacting tolerance during the manufacturing process in accordance with American National Standards Institute (ANSI) definitions to provide a close tolerance fit within a mating bearing sleeve. The present impeller hub is also finish ground in accordance with ANSI definitions to reduce surface friction and to provide an optimal sealing surface for engagement with a radial seal, which is disposed about the impeller hub sealing it to prevent contaminants from entering the hydraulic pump of the transmission. The present impeller hub also includes additional structural features such as fillet radii machined on selected features to facilitate assembly of the torque converter.

US Patent:

7296666, Nov 20, 2007

Filed:

Jun 29, 2005

Appl. No.:

11/174267

Inventors:

Michael G. Morin - Keene NH, US

Assignee:

Sonnax Industries, Inc. - Bellews Falls VT

International Classification:

F16H 45/02

US Classification:

192 328

Abstract:

A heavy-duty replacement torque converter cover for an automatic transmission designed to withstand the mechanical stresses generated during the torque converter lock-up cycle and other peak torque events in diesel engine pick-up trucks is disclosed. The present cover includes an internal spline that achieves up to a 70% increase in spline tooth engagement with a mating friction plate in the lock-up clutch in comparison to the original equipment cover providing increased torque capacity to the lock-up clutch. This is accomplished by machining a true internal spline within the cover on gear shaping equipment instead of utilizing the so-called Grob cold forming method, which provides only a simulated internal spline comprised of interlocking embossments having substantially less torque capacity than the present internal spline. The present cover also provides a thicker lock-up clutch surface, increased structural support for stud weldments, reduced stress cracking, improved heat dissipation, and increased service longevity.

US Patent:

20220195236, Jun 23, 2022

Filed:

Dec 22, 2021

Appl. No.:

17/558850

Inventors:

- Somerville MA, US
Luke Kwisnek - Somerville MA, US
Michael Morin - Somerville MA, US

Assignee:

Formlabs, Inc. - Somerville MA

International Classification:

C09D 163/10
C08G 59/24
C08G 59/17
C08G 59/40
C08G 59/68
B33Y 70/00
B33Y 40/20
B29C 64/30

Abstract:

A multi-component composition for additive manufacturing, and related methods, are generally described.

US Patent:

20210347895, Nov 11, 2021

Filed:

Oct 17, 2019

Appl. No.:

17/283614

Inventors:

- Exton PA, US
Michael John MORIN - Salisbury MA, US

International Classification:

C07K 16/28

Abstract:

The inventions described herein are directed to bispecific antibodies that are capable of selectively targeting exosomes by specifically binding a first exosome-associated protein and Programmed Death Ligand-1 (“PD-L1”) as a second exosome-associated protein. These bispecific antibodies can disrupt the suppression of anti-tumor activity by immune cells by targeting tumor-cell derived exosomes that inhibit T cell activation. Therefore, bispecific antibodies of the invention can be used in methods for treating cancers.

US Patent:

20210221914, Jul 22, 2021

Filed:

May 17, 2019

Appl. No.:

17/055646

Inventors:

- Exton PA, US
Michael John MORIN - Salisbury MA, US

Assignee:

IMMUNOME, INC. - Exton PA

International Classification:

C07K 16/42

Abstract:

This invention relates to the incorporation of one, or more, heterologous antibody epitopes into the AB, EF, or CD structural loops of the constant heavy domain 3 (“CH3 domain”) of an engineered antibody or Fc-linked therapeutic agent. The heterologous epitopes serve as “epitope tags” that are specifically detectable by epitope tag-specific detector antibodies, irrespective of the tagged agent's target specificity. Therefore, the epitope tags are useful for the rapid detection of any tagged antibody or Fc-linked agent in biological samples, including samples, which also contain endogenous antibodies.

US Patent:

20210206818, Jul 8, 2021

Filed:

Jan 20, 2017

Appl. No.:

16/071131

Inventors:

- Cambridge MA, US
Joshua P. FREDERICK - Charlestown MA, US
Kristine MCKINNEY - Cambridge MA, US
Christina HENDERSON - Stow MA, US
Kahlin CHEUNG-ONG - Boston MA, US
Joseph BOLEN - Cambridge MA, US
Stephen Michael KELSEY - Brookline MA, US
Michael MORIN - Salisbury MA, US
Sushma GURUMURTHY - Sharon MA, US
Kerry BENENATO - Sudbury MA, US
Stephen HOGE - Brookline MA, US
Iain MCFADYEN - Arlington MA, US
Vladimir PRESNYAK - Manchester NH, US

International Classification:

C07K 14/47
A61K 9/51
A61P 35/00

Abstract:

The invention features isolated mRNAs encoding at least one intracellular binding domain, including mRNAs comprising one or more modified nucleobase and preferably lacking an encoded scaffold polypeptide, and methods of using the same, for example, for inducing apoptosis and/or treating cancer (e.g., liver cancer or colorectal cancer).