Mark Cook - Madison WI Ming-der Yang - Madison WI Michael W Pariza - Madison WI
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 3120
US Classification:
514560
Abstract:
Administering conjugated linoleic acid to human and non-human animals having conditions associated with the existence of autoimmune complexes or auto-immune reactive cells can extend the survival life time, prolong healthy tissue and organ function and prevent body weight wasting in these animals.
Method For Reducing Adverse Effects Of A Weight Loss Regimen
A method for reducing certain effects associated with a negative calorie balance in a human includes the step of administering conjugated linoleic acid to a human in an amount effective to reduce at least one of the effects.
Mark E. Cook - Madison WI, US Michael W Pariza - Madison WI, US Yeonhwa Park - Madison WI, US Guangming Li - Madison WI, US
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K031/20
US Classification:
514560
Abstract:
The present invention provides a method of using conjugated nonadecadienoic acid (CNA), one of its derivatives, or a combination thereof to inhibit lipoprotein lipase activity associated with a cell, to control body fat in a human or non-human animal, to inhibit cyclooxygenase activity in a cell, to inhibit platelet aggregation in a human or non-human animal, and to prevent or treat a condition or disease related to platelet aggregation.
Michael W. Pariza - Madison WI, US Yeonhwa Park - Madison WI, US
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 31/00 A61K 31/045
US Classification:
514734, 514736, 514739
Abstract:
A method for controlling body fat in a human or nonhuman animal includes the step of reducing lipoxygenase activity in an animal. Lipoxygenase activity can be reduced by reducing the enzyme activity or by lowering the enzyme level. Reduced lipoxygenase activity correlates with reduced cell-associated LPL activity and with reduced cellular triacylglyceride level.
Methods Of Chelating Metal And Novel Compositions Therefor
Michael W. Pariza - Madison WI Yeong L. Ha - Madison WI
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 3122 A61K 3120
US Classification:
514549
Abstract:
A method of chelating a metal in solution comprise adding to the solution a safe and effective amount of an active form of CLA. Pharmaceutical preparations for practice of the method in vivo are disclosed.
Mark E Cook - Madison WI Leah D Whigham - Madison WI Michael W Pariza - Madison WI
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 31201
US Classification:
514560
Abstract:
Disclosed is a method for selectively inhibiting cyclooxygenase-2 in an animal having a cyclooxygenase-2 activity by delivering into the animal an amount of a conjugated linoleic acid effective to reduce cyclooxygenase-2 activity in the animal.
Methods Of Preventing Oxidation, Quenching Singlet Oxygen And Inhibiting Mold Growth And Novel Compositions Therefor
Michael W. Pariza - Madison WI Yeong L. Ha - Madison WI
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 3120 A61K 3100
US Classification:
514558
Abstract:
Methods of preventing oxidation, quenching singlet oxygen and inhibiting mold growth in a product comprises adding to the product a safe and effective amount of an active form of CLA. Active forms of CLA include 9,11-octadecadoenoic acid, 10,12-octadecadienoic acid, active isomers thereof, non-toxic salts thereof; active esters; other active chemical derivatives thereof, and mixtures thereof. Simple methods of making the compositions and novel compositions are also disclosed.
Use Of Cla To Reduce The Incidence Of Valgus And Varus Leg Deforomities In Poultry
Mark E. Cook - Madison WI Michael W. Pariza - Madison WI Daria L. Jerome - Middleton WI
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 3120
US Classification:
514560
Abstract:
Methods of treating a bird to prevent skeletal problems consist of administering to the bird a safe and effective amount of CLA (conjugated linoleic acid).