Michael J Reifler

US Patent:

6956114, Oct 18, 2005

Filed:

Apr 11, 2002

Appl. No.:

10/122706

Inventors:

Maithreyan Srinivasan - Hamden CT, US
Michael Reifler - Hamden CT, US

Assignee:

'454 Corporation - Branford CT

International Classification:

C07H021/04
C12N009/12
C12N009/02
C12N001/21
C12N015/52

US Classification:

536 232, 536 234, 435194, 435189, 4352523, 4353201, 435325, 435353, 435354, 435366

Abstract:

The present invention relates to the field of DNA recombinant technology. More specifically, this invention relates to fusion proteins comprising an ATP generating polypeptide joined to a polypeptide that converts ATP into a detectable entity. Accordingly, this invention focuses on sulfurylase-luciferase fusion proteins. This invention also relates to pharmaceutical compositions containing the fusion proteins and methods for using them.

US Patent:

20030113747, Jun 19, 2003

Filed:

May 23, 2002

Appl. No.:

10/154515

Inventors:

Maithreyan Srinivasan - Branford CT, US
Michael Reifler - Hamden CT, US

International Classification:

C12Q001/68
C07H021/04
C12N009/22
C12P021/02
C12N001/21
C12N015/74

US Classification:

435/006000, 435/069100, 435/199000, 435/252300, 435/252310, 435/320100, 536/023200

Abstract:

The present invention relates to the field of DNA recombinant technology. More specifically, this invention relates to fusion proteins comprising an ATP generating polypeptide joined to a polypeptide that converts ATP into a detectable entity. Accordingly, this invention focuses on sulfurylase-luciferase fusion proteins. This invention also relates to pharmaceutical compositions containing the fusion proteins and methods for using them.

US Patent:

20050124022, Jun 9, 2005

Filed:

Oct 30, 2002

Appl. No.:

10/494073

Inventors:

Maithreyan Srinivasan - Hamden CT, US
Michael Reifler - Hamden CT, US

International Classification:

C12Q001/42
C12N009/10
C12N009/12
C12N001/21

US Classification:

435021000, 435194000, 435193000, 435252300

Abstract:

The present invention relates to the field of DNA recombinant technology. More specifically, this invention relates to fusion proteins comprising an ATP generating polypeptide joined to a polypeptide that converts ATP into a detectable entity. Accordingly, this invention focuses on sulfurylase-luciferase fusion proteins. This invention also relates to pharmaceutical compositions containing the fusion proteins and methods for using them.

US Patent:

20060078909, Apr 13, 2006

Filed:

Jun 7, 2005

Appl. No.:

11/147763

Inventors:

Maithreyan Srinivasan - Branford CT, US
Michael Reifler - Hamden CT, US

International Classification:

C12Q 1/68
C12N 9/06

US Classification:

435006000, 435191000

Abstract:

The present invention relates to the field of DNA recombinant technology. More specifically, this invention relates to fusion proteins comprising an ATP generating polypeptide joined to a polypeptide that converts ATP into a detectable entity. Accordingly, this invention focuses on sulfurylase-luciferase fusion proteins. This invention also relates to pharmaceutical compositions containing the fusion proteins and methods for using them.