Michael P Schaffer

US Patent:

8084215, Dec 27, 2011

Filed:

Apr 29, 2008

Appl. No.:

12/111914

Inventors:

Virginia Hill - Los Angeles CA, US
Mohammad Atefi - Los Angeles CA, US
Michael I. Schaffer - Los Angeles CA, US

Assignee:

Psychemedics Corporation - Acton MA

International Classification:

G01N 33/53

US Classification:

435 71, 435 792, 435962, 436541

Abstract:

Methods that permit the rapid release of one or more analytes from head or body hair or other keratinized structures of an individual (who may previously have ingested one or more of the analytes) are provided. The methods can include contacting the keratinized structure with a reducing agent but not with a proteolytic agent. The methods can further include identification and quantification of the one or more analytes by known analytical techniques such as immunoassays. The described methods do not damage the analyte and do not cause harmful effects on a subsequently-used analyte detection probe (e. g. , an antibody).

US Patent:

8329417, Dec 11, 2012

Filed:

Dec 23, 2011

Appl. No.:

13/336119

Inventors:

Virginia Hill - Los Angeles CA, US
Mohammad Atefi - Los Angeles CA, US
Michael I. Schaffer - Los Angeles CA, US

Assignee:

Psychemedics Corporation - Acton MA

International Classification:

G01N 33/53

US Classification:

435 71, 435 792, 435692, 436541

Abstract:

Methods that permit the rapid release of one or more analytes from head or body hair or other keratinized structures of an individual (who may previously have ingested one or more of the analytes) are provided. The methods can include contacting the keratinized structure with a reducing agent but not with a proteolytic agent. The methods can further include identification and quantification of the one or more analytes by known analytical techniques such as immunoassays. The described methods do not damage the analyte and do not cause harmful effects on a subsequently-used analyte detection probe (e. g. , an antibody).

US Patent:

8435747, May 7, 2013

Filed:

Apr 29, 2009

Appl. No.:

12/990447

Inventors:

Virginia Hill - Los Angeles CA, US
Mohammad Atefi - Los Angeles CA, US
Michael I. Schaffer - Los Angeles CA, US

Assignee:

Psychemedics Corporation - Acton MA

International Classification:

G01N 33/53

US Classification:

435 71, 436518

Abstract:

Methods that permit the rapid release of one or more analytes from head or body hair or other keratinized structures of an individual (who may previously have ingested one or more of the analytes) are provided. The methods can include contacting the keratinized structure with a reducing agent but not with a proteolytic agent. The methods can further include identification and quantification of the one or more analytes by known analytical techniques such as immunoassays. The described methods do not damage the analyte and do not cause harmful effects on a subsequently-used analyte detection probe (e. g. , an antibody).

US Patent:

20110118138, May 19, 2011

Filed:

Apr 29, 2009

Appl. No.:

12/990451

Inventors:

Virginia Hill - Los Angeles CA, US
Mohammad Atefi - Los Angeles CA, US
Michael I. Schaffer - Los Angeles CA, US

International Classification:

C40B 30/04
G01N 33/543
G01N 33/53
C40B 40/00
C40B 40/04

US Classification:

506 9, 436518, 435 79, 435 71, 506 13, 506 15

Abstract:

Compositions and methods for detecting the presence and/or amount of one or more analytes, including analytes such as drugs of abuse, are provided. The compositions include two or more analytes associated with a solid phase, e.g., a particle or a multiwell plate. The compositions and methods also allow the simultaneous, tandem, or serial determination of the presence and/or amount of two or more analytes of interest in a sample.

US Patent:

20140004534, Jan 2, 2014

Filed:

Jun 28, 2013

Appl. No.:

13/931169

Inventors:

Michael I. Schaffer - Los Angeles CA, US

International Classification:

G01N 21/64

US Classification:

435 79, 436501

Abstract:

Compositions and methods for detecting the presence and/or amount of one or more analytes, including analytes such as drugs of abuse in a hair wash sample are provided. The compositions include two or more analytes associated with a solid phase, e.g., a particle or a multiwell plate. The compositions and methods also allow the simultaneous, tandem, or serial determination of the presence and/or amount of two or more analytes of interest in a hair wash sample.

US Patent:

50390392, Aug 13, 1991

Filed:

Jan 4, 1990

Appl. No.:

7/460820

Inventors:

Michael D. Schaffer - Santa Clara CA

International Classification:

F16L 300

US Classification:

248 59

Abstract:

Presented is a generally L-shaped pre-manufactured bracket designed for application to installed hanger rods in concrete buildings to provide a means of installing and supporting a cross-beam which, in turn, is utilized to support additional equipment, such as electrical conduits and pipes.

US Patent:

49223070, May 1, 1990

Filed:

Jun 30, 1988

Appl. No.:

7/213852

Inventors:

Michael J. Schaffer - Torrance CA

Assignee:

Hughes Aircraft Company - Los Angeles CA

International Classification:

G01C 308
G01B 1114

US Classification:

356 5

Abstract:

This invention provides apparatus and method to increase the direct measurement accuracy of a rotary encoder type of micrometer 10. To overcome a maximum measurement accuracy of 100 microinches there is provided a laser displacement meter which includes a laser head 24 which is coupled to a micrometer bed 12 by a pair of of clamps 26a and 26b and by a magnetic plate 28. Laser head 24 has an output display 30 associated therewith for indicating the magnitude of the measurement made by the laser head 24. Laser head 24 is operable for providing an output chirped laser beam 32 and for receiving a reflected output beam 34. A corner cube reflector 36 is mounted by an arm 38 to a headstock spindle 18. The reflected return beam is detected and processed by a phase demodulator and converted into pulses. The pulses are counted and converted to distance and displayed.

US Patent:

20210048436, Feb 18, 2021

Filed:

Sep 13, 2019

Appl. No.:

16/570667

Inventors:

- Acton MA, US
Elvan Loni - Torrance CA, US
Virginia Ann Hill - Los Angeles CA, US
Michael Irving Schaffer - Los Angeles CA, US

International Classification:

G01N 33/573
G01N 33/94

Abstract:

This disclosure relates to methods and kits for determining the presence and/or amount of one or more analytes in a keratinized structure (e.g., hair) sample.