Adair J. Hotchkiss - Half Moon Bay CA John V. O'Connor - San Carlos CA Michael W. Spellman - San Bruno CA
Assignee:
Genentech, Inc. - So. San Francisco CA
International Classification:
A61K 3849 C07K 14435 C12N 948
US Classification:
424 9464
Abstract:
Novel human tissue-type plasminogen activator variant that a) retains substantially full biological activity b) has a modified carbohydrate structure and c) has an altered in vivo half-life. Means for preparation of the variants and results of assays measuring function of the activators are also disclosed.
Adair J. Hotchkiss - Half Moon Bay CA John V. O'Connor - San Carlos CA Michael W. Spellman - San Bruno CA
Assignee:
Genentech, Inc. - San Bruno CA
International Classification:
A61K 3849 C12N 1558
US Classification:
435 691
Abstract:
Novel human tissue-type plasminogen activator variant that a) retains substantially full biological activity b) has a modified carbohydrate structure and c) has an altered in vivo half-life. Means for preparation of the variants and results of assays measuring function of the activators are also disclosed.
Name / Title
Company / Classification
Phones & Addresses
Michael Spellman Engineer
Dynogen Pharmaceuticals, Inc Commercial Physical and Biological Research
52 2Nd Ave, Waltham, MA 02451
Michael Spellman Director
WAYLAND-WESTON ROWING ASSOCIATION, INC
6 Pesce Dr, Wayland, MA 01778 2 Hastings Rd, Weston, MA 02493
Pharmaceutical Development Consultant at Self Employed (Self-employed)
Location:
Greater Boston Area
Industry:
Biotechnology
Work:
Self Employed since Oct 2008
Pharmaceutical Development Consultant
Dynogen Pharmaceuticals, Inc. Jan 2003 - Sep 2008
SVP, Pharmaceutical Development
Millennium Pharmaceuticals Aug 2000 - Dec 2002
VP,Quality, Process Development,
Coulter Pharmaceuticals Mar 1998 - Jul 2000
VP, Preclinical Development
Genentech Aug 1984 - Mar 1998
Director, Pharmacokinetics and Metabolism
Education:
Michigan State University 1983
PhD, Biochemistry
Assumption College 1970 - 1974
BA, Natural Science
Sales Director, Global Cash at State Street Global Advisors
Location:
Greater Boston Area
Industry:
Investment Management
Work:
State Street Global Advisors - Greater Boston Area since May 2012
Sales Director, Global Cash
BlackRock - Greater Boston Area Oct 2006 - May 2012
Director, Cash Management - US FI Team
Merrill Lynch Investment Managers Sep 2002 - 2006
Vice President
Merrill Lynch Jun 2000 - Sep 2002
Analyst
Education:
Suffolk University - Sawyer School of Management 2005 - 2009
MBA, Finance
Saint Anselm College 1996 - 2000
BA, cum laude, Financial Economics
Arlington Catholic High School 1992 - 1996
Boston Cars Braintree, MA Feb 2005 to May 2008 Auto Detailer/ Building MaintenanceHVAC Ayer, MA 2004 to 2004 InstallerGuthrie Bros. Landscaping Shirley, MA 2003 to 2004 LaborerBrooks Automation Chelmsford, MA 1999 to 2002 IT TechnicianComet Products Chelmsford, MA 1988 to 1997 Thermoforming Machine Operator
Skills:
Use tools ranging from common hand and power tools, such as hammers, hoists, saws, drills, and wrenches, to precision measuring instruments and electrical and electronic testing devices.
Vincent Althaus, Harry Adrian, Richard Geimer, Francis Nichols, Bill Gregory, Jack Hanses, Thomas Hennessy, Richard Puhl, Thomas Carney, Thomas Kelly, John Cull, Richard Mann