Michael B Thornton

US Patent:

20130059738, Mar 7, 2013

Filed:

Oct 29, 2012

Appl. No.:

13/663334

Inventors:

Life Technologies Corporation - Carlsbad CA, US
Mark ANDERSEN - Carlsbad CA, US
Michael THORNTON - San Francisco CA, US

Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA

International Classification:

C40B 20/00

US Classification:

506 2

Abstract:

The present invention provides methods, compositions, kits, systems and apparatus that are useful for determining copy number variation of one or more nucleic acids present in a sample. In some aspects, the method includes various target-specific primers that allow for the selective amplification of one or more target nucleic acids in the sample. In yet another aspect, the invention relates to determining copy number variation with respect to gene or chromosome representation of a nucleic acid in the sample. In some aspects, the method for determining copy number variation of different target nucleic acids in a sample using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including diagnosis, predictive therapeutic regimes or other therapeutic purposes.

US Patent:

20130059762, Mar 7, 2013

Filed:

Nov 16, 2012

Appl. No.:

13/679706

Inventors:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA, US
Mark ANDERSEN - Carlsbad CA, US
Michael THORNTON - San Francisco CA, US

Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA

International Classification:

C40B 50/06

US Classification:

506 26

Abstract:

The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.

US Patent:

20210032679, Feb 4, 2021

Filed:

Oct 15, 2020

Appl. No.:

16/949159

Inventors:

- Carlsbad CA, US
Mark ANDERSEN - Carlsbad CA, US
Michael THORNTON - San Francisco CA, US

International Classification:

C12Q 1/686
C12Q 1/6806
C12Q 1/6855
C12N 15/10
C12Q 1/6886
C12Q 1/6874

Abstract:

The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.

US Patent:

20180245134, Aug 30, 2018

Filed:

Apr 27, 2018

Appl. No.:

15/965595

Inventors:

- Carlsbad CA, US
Mark ANDERSEN - Carlsbad CA, US
Michael THORNTON - San Francisco CA, US

International Classification:

C12Q 1/686
C12N 15/10
C12Q 1/6855
C12Q 1/6874
C12Q 1/6806
C12Q 1/6886

Abstract:

The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.

US Patent:

20180245135, Aug 30, 2018

Filed:

Apr 27, 2018

Appl. No.:

15/965650

Inventors:

- Carlsbad CA, US
Mark ANDERSEN - Carlsbad CA, US
Michael THORNTON - San Francisco CA, US

International Classification:

C12Q 1/686
C12N 15/10
C12Q 1/6855
C12Q 1/6874
C12Q 1/6806
C12Q 1/6886

Abstract:

The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.

US Patent:

20160046979, Feb 18, 2016

Filed:

Jul 9, 2015

Appl. No.:

14/795826

Inventors:

- Carlsbad CA, US
Mark Andersen - Carlsbad CA, US
Michael Thornton - San Francisco CA, US

International Classification:

C12Q 1/68

Abstract:

The present invention provides methods, compositions, kits, systems and apparatus that are useful for determining copy number variation of one or more nucleic acids present in a sample. In some aspects, the method includes various target-specific primers that allow for the selective amplification of one or more target nucleic acids in the sample. In yet another aspect, the invention relates to determining copy number variation with respect to gene or chromosome representation of a nucleic acid in the sample. In some aspects, the method for determining copy number variation of different target nucleic acids in a sample using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including diagnosis, predictive therapeutic regimes or other therapeutic purposes.

US Patent:

20150322490, Nov 12, 2015

Filed:

Jul 10, 2015

Appl. No.:

14/796400

Inventors:

- Carlsbad CA, US
Mark Andersen - Carlsbad CA, US
Michael Thornton - San Francisco CA, US

International Classification:

C12Q 1/68

Abstract:

The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.

US Patent:

20150307920, Oct 29, 2015

Filed:

Jul 10, 2015

Appl. No.:

14/796696

Inventors:

- Carlsbad CA, US
Mark Andersen - Carlsbad CA, US
Michael Thornton - San Francisco CA, US

International Classification:

C12Q 1/68

Abstract:

The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.

Address:

33375 Crestview Dr, Temecula, CA 92592

VIN:

1G1ZC5E10BF378731

Make:

CHEVROLET

Model:

MALIBU

Year:

2011