Michael D Weir

US Patent:

7713542, May 11, 2010

Filed:

May 18, 2005

Appl. No.:

11/132028

Inventors:

Huakun Xu - Frederick MD, US
Michael D. Weir - Silver Spring MD, US

Assignee:

ADA Foundation - Chicago IL

International Classification:

A61F 2/02

US Classification:

424426, 424422, 424484, 424 937, 623 1611, 623 2356, 623 2361, 623 2362

Abstract:

Living cellular material is encapsulated or placed in a protective material (cell protector) which is biocompatible, biodegradable and has a three-dimensional form. The three dimensional form is incorporated into a matrix that maybe implanted in vivo, ultimately degrade and thereby by replaced by living cell generated material.

US Patent:

20100247605, Sep 30, 2010

Filed:

May 10, 2010

Appl. No.:

12/776952

Inventors:

Huakun Xu - Frederick MD, US
Michael D. Weir - Silver Spring MD, US

Assignee:

American Dental Association Foundation - Chicago IL

International Classification:

A61K 35/00
A61F 2/00
A61P 19/08
A61P 19/04

US Classification:

424423, 424 931

Abstract:

Living cellular material is encapsulated or placed in a protective material (cell protector) which is biocompatible, biodegradable and has a three-dimensional form. The three dimensional form is incorporated into a matrix that maybe implanted in vivo, ultimately degrade and thereby by replaced by living cell generated material.

US Patent:

20130039990, Feb 14, 2013

Filed:

Apr 29, 2011

Appl. No.:

13/695122

Inventors:

Huakun Xu - Frederick MD, US
Michael Weir - Silver Spring MD, US

Assignee:

UNIVERSITY OF MARYLAND, BALTIMORE - Baltimore MD

International Classification:

A61K 9/50
A61K 35/32
A61K 35/44
A61K 9/14
A61K 35/54
A61P 19/08
A61K 47/42
A61K 35/12
A61K 35/28

US Classification:

424492, 424490, 424493, 424497, 424 937, 424491, 514773, 424400

Abstract:

The invention provides injectable, stem cell-containing calcium phosphate bone pastes for bone tissue engineering and methods of making and using the same.

US Patent:

20230130513, Apr 27, 2023

Filed:

Oct 20, 2022

Appl. No.:

17/970448

Inventors:

- Baltimore MD, US
Michael D. Weir - Silver Spring MD, US
Huakun Xu - Frederick MD, US

Assignee:

University of Maryland, Baltimore - Baltimore MD

International Classification:

A61K 9/107
A61K 9/51
A61K 9/00
A61P 31/04
A61P 1/02
A61Q 11/00
A61K 41/00
A61K 33/26
A61K 8/06
A61K 8/19
A61K 8/49
A61N 5/06

Abstract:

Provided herein are magnetically-responsive, photosensitizer based antimicrobial microemulsions and photodynamic nanoplatforms in which a photosensitizer functionally associated with a plurality of superparamagnetic iron oxide nanoparticles are encapsulated. Also provided are methods and processes utilizing the antimicrobial microemulsions and photodynamic nanoplatforms to treat an oral disease, to reduce a microbial population in a pathogenic oral biofilm and to improve the efficacy of a photosensitizer during an antimicrobial photodynamic therapy treatment of an oral disease.

US Patent:

20170112723, Apr 27, 2017

Filed:

Jan 6, 2017

Appl. No.:

15/399869

Inventors:

- Baltimore MD, US
Michael WEIR - Silver Spring MD, US

Assignee:

UNIVERSITY OF MARYLAND, BALTIMORE - Baltimore MD

International Classification:

A61K 6/00
A61K 6/083
A61K 6/06

Abstract:

The present invention provides dental bonding agents and dental bonding systems comprising the dental bonding agents. The dental bonding agents of the invention are characterized by having antibacterial properties, and in some aspects of the invention, remineralizing properties.

US Patent:

20160228335, Aug 11, 2016

Filed:

Feb 5, 2016

Appl. No.:

15/017123

Inventors:

- Baltimore MD, US
Michael D. WEIR - Silver Spring MD, US
Ling ZHANG - Xi'an, CN

Assignee:

University of Maryland, Baltimore - Baltimore MD

International Classification:

A61K 6/033
A61K 6/00
A61K 6/083

Abstract:

The present invention provides rechargeable dental materials that can be widely applied in a variety of dental applications. The rechargeable dental materials of the invention may be included in dental primers, dental adhesives, dental resins, dental composites, dental bonding systems and the like, as well as dental cements, dental sealants, dental bases and dental liners, each of which is rechargeable with calcium and phosphate ions. The present invention also provides for a method of recharging the rechargeable dental material with calcium and phosphate ions.

US Patent:

20160058675, Mar 3, 2016

Filed:

Feb 8, 2013

Appl. No.:

14/377313

Inventors:

Huakun XU - Frederick MD, US
Michael WEIR - Silver Spring MD, US

International Classification:

A61K 6/00
A61K 6/02

Abstract:

The present invention provides dental bonding agents and dental bonding systems comprising the dental bonding agents. The dental bonding agents of the invention are characterized by having antibacterial properties, and in some aspects of the invention, remineralizing properties.

US Patent:

20150299345, Oct 22, 2015

Filed:

Sep 19, 2013

Appl. No.:

14/436377

Inventors:

Huakun XU - Frederick MD, US
Michael WEIR - Silver Spring MD, US

Assignee:

UNIVERSITY OF MARYLAND, BALTIMORE - Baltimore MD

International Classification:

C08F 20/34
A61Q 11/00
A61K 8/02
A61K 8/26
A61K 8/24
A61K 8/81
A61K 8/19

Abstract:

Provided herein are antibacterial monomers, antibacterial resins comprising a resin and the monomers, and dental composites comprising the antibacterial resins and a filler, and methods of making the same. The dental composite can optionally contain amorphous calcium phosphate nanoparticles. The dental composites display strongly antibacterial properties, increased calcium and phosphate ion release, and improved mechanical properties.