Michael G Weir

US Patent:

20230130513, Apr 27, 2023

Filed:

Oct 20, 2022

Appl. No.:

17/970448

Inventors:

- Baltimore MD, US
Michael D. Weir - Silver Spring MD, US
Huakun Xu - Frederick MD, US

Assignee:

University of Maryland, Baltimore - Baltimore MD

International Classification:

A61K 9/107
A61K 9/51
A61K 9/00
A61P 31/04
A61P 1/02
A61Q 11/00
A61K 41/00
A61K 33/26
A61K 8/06
A61K 8/19
A61K 8/49
A61N 5/06

Abstract:

Provided herein are magnetically-responsive, photosensitizer based antimicrobial microemulsions and photodynamic nanoplatforms in which a photosensitizer functionally associated with a plurality of superparamagnetic iron oxide nanoparticles are encapsulated. Also provided are methods and processes utilizing the antimicrobial microemulsions and photodynamic nanoplatforms to treat an oral disease, to reduce a microbial population in a pathogenic oral biofilm and to improve the efficacy of a photosensitizer during an antimicrobial photodynamic therapy treatment of an oral disease.

US Patent:

20170112723, Apr 27, 2017

Filed:

Jan 6, 2017

Appl. No.:

15/399869

Inventors:

- Baltimore MD, US
Michael WEIR - Silver Spring MD, US

Assignee:

UNIVERSITY OF MARYLAND, BALTIMORE - Baltimore MD

International Classification:

A61K 6/00
A61K 6/083
A61K 6/06

Abstract:

The present invention provides dental bonding agents and dental bonding systems comprising the dental bonding agents. The dental bonding agents of the invention are characterized by having antibacterial properties, and in some aspects of the invention, remineralizing properties.

US Patent:

20160228335, Aug 11, 2016

Filed:

Feb 5, 2016

Appl. No.:

15/017123

Inventors:

- Baltimore MD, US
Michael D. WEIR - Silver Spring MD, US
Ling ZHANG - Xi'an, CN

Assignee:

University of Maryland, Baltimore - Baltimore MD

International Classification:

A61K 6/033
A61K 6/00
A61K 6/083

Abstract:

The present invention provides rechargeable dental materials that can be widely applied in a variety of dental applications. The rechargeable dental materials of the invention may be included in dental primers, dental adhesives, dental resins, dental composites, dental bonding systems and the like, as well as dental cements, dental sealants, dental bases and dental liners, each of which is rechargeable with calcium and phosphate ions. The present invention also provides for a method of recharging the rechargeable dental material with calcium and phosphate ions.