Michele E Ball

US Patent:

6878749, Apr 12, 2005

Filed:

Jan 16, 2003

Appl. No.:

10/345908

Inventors:

Marjorie Regan Gatlin - Hoboken NJ, US
Michele Ann Ball - Morris Plains NJ, US
Richard Owen Mannion - Mount Arlington NJ, US
Anees Abdulquadar Karnachi - Hillsborough NJ, US
Christiane Guitard - Hegenheim, FR
Malcolm Allison - Basel, CH

Assignee:

Novartis AG - Basel

International Classification:

A61K031/13
A61K031/70
A61K031/715

US Classification:

514641, 514 23, 514 57

Abstract:

The invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, which comprises nateglinide (1) stet or repaglinide and at least one other antidiabetic compound selected from the group consisting of thiazolidinedione derivatives (glitazones), sulfonyl urea derivatives and metformin for simultaneous, separate or sequential use in the prevention, delay of progression or treatment of diseases, especially metabolic disorders and in particular type 2 diabetes and diseases and conditions associated with diabetes; to a composition, respectively, which comprises nateglinide and a pharmaceutically acceptable carrier and to a process of making such composition; the use of such combination or composition for the preparation of a medicament for the prevention, delay of progression or treatment of metabolic disorders; a method of prevention, delay of progression or treatment of diseases in warm-blooded animals; the use of such combination or composition for the cosmetic treatment of a mammal in order to effect a cosmetically beneficial loss of body weight; and to a method of improving the bodily appearance of a warm-blooded animal.

US Patent:

20050124663, Jun 9, 2005

Filed:

Jan 14, 2005

Appl. No.:

11/036842

Inventors:

Marjorie Gatlin - Hoboken NJ, US
Michele Ball - Morris Plains NJ, US
Richard Mannion - Mount Arlington NJ, US
Anees Karnachi - Hillsborough NJ, US
Christiane Guitard - Hegenheim, FR
Malcolm Allison - Basel, CH

International Classification:

A61K031/4439
A61K031/426
A61K031/198
A61K031/175
A61K031/155

US Classification:

514340000, 514369000, 514563000, 514635000, 514592000

Abstract:

The invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, which comprises nateglinide (I) or repaglinide and at least one other antidiabetic compound selected from the group consisting of thiazolidinedione derivatives (glitazones), sulfonyl urea derivatives and metformin for simultaneous, separate or sequential use in the prevention, delay of progression or treatment of diseases, especially metabolic disorders and in particular type 2 diabetes and diseases and conditions associated with diabetes; to a composition, respectively, which comprises nateglinide and a pharmaceutically acceptable carrier and to a process of making such composition; the use of such combination or composition for the preparation of a medicament for the prevention, delay of progression or treatment of metabolic disorders; a method of prevention, delay of progression or treatment of diseases in warm-blooded animals; the use of such combination or composition for the cosmetic treatment of a mammal in order to effect a cosmetically beneficial loss of body weight; and to a method of improving the bodily appearance of a warm-blooded animal.

US Patent:

20070275928, Nov 29, 2007

Filed:

Jul 23, 2007

Appl. No.:

11/781630

Inventors:

Marjorie Gatlin - Hoboken NJ, US
Michele Ball - Morris Plains NJ, US
Richard Mannion - Mount Arlington NJ, US
Anees Karnachi - Hillsborough NJ, US
Christiane Guitard - Hegenheim, FR
Malcolm Allison - Basel, CH

International Classification:

A61K 31/197
A61K 31/717
A61P 3/04
A61P 3/10

US Classification:

514057000, 514023000, 514567000

Abstract:

The invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, which comprises nateglinide (I) or repaglinide and at least one other antidiabetic compound selected from the group consisting of thiazolidinedione derivatives (glitazones), sulfonyl urea derivatives and metformin for simultaneous, separate or sequential use in the prevention, delay of progression or treatment of diseases, especially metabolic disorders and in particular type 2 diabetes and diseases and conditions associated with diabetes; to a composition, respectively, which comprises nateglinide and a pharmaceutically acceptable carrier and to a process of making such composition; the use of such combination or composition for the preparation of a medicament for the prevention, delay of progression or treatment of metabolic disorders; a method of prevention, delay of progression or treatment of diseases in warm-blooded animals; the use of such combination or composition for the cosmetic treatment of a mammal in order to effect a cosmetically beneficial loss of body weight; and to a method of improving the bodily appearance of a warm-blooded animal.

US Patent:

20100076084, Mar 25, 2010

Filed:

Nov 24, 2009

Appl. No.:

12/624976

Inventors:

Marjorie Regan Gatlin - Hoboken NJ, US
Michele Ann Ball - Morris Plains NJ, US
Richard Owen Mannion - Mount Arlington NJ, US
Anees Abdulquadar Karnachi - Hillsborough NJ, US
Christiane Guitard - Hegenheim, FR
Malcolm Allison - Basel, CH

International Classification:

A61K 31/165
A61P 3/10

US Classification:

514617

Abstract:

The invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, which comprises nateglinide (I)or repaglinide and at least one other antidiabetic compound selected from the group consisting of thiazolidinedione derivatives (glitazones), sulfonyl urea derivatives and metformin for simultaneous, separate or sequential use in the prevention, delay of progression or treatment of diseases, especially metabolic disorders and in particular type 2 diabetes and diseases and conditions associated with diabetes; to a composition, respectively, which comprises nateglinide and a pharmaceutically acceptable carrier and to a process of making such composition; the use of such combination or composition for the preparation of a medicament for the prevention, delay of progression or treatment of metabolic disorders; a method of prevention, delay of progression or treatment of diseases in warm-blooded animals; the use of such combination or composition for the cosmetic treatment of a mammal in order to effect a cosmetically beneficial loss of body weight; and to a method of improving the bodily appearance of a warm-blooded animal.

US Patent:

6559188, May 6, 2003

Filed:

Sep 15, 2000

Appl. No.:

09/663264

Inventors:

Marjorie Regan Gatlin - Hoboken NJ
Michele Ann Ball - Morris Plains NJ
Richard Owen Mannion - Mount Arlington NJ
Anees Abdulquadar Karnachi - Hillsborough NJ
Christiane Guitard - Hegenheim, FR
Malcolm Allison - Basel, CH

Assignee:

Novartis AG - Basel

International Classification:

A61K 3113

US Classification:

514641, 514 23, 514 57, 514866

Abstract:

The invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, which comprises nateglinide (I) or repaglinide and at least one other antidiabetic compound selected from the group consisting of thiazolidinedione derivatives (glitazones), sulfonyl urea derivatives and metformin for simultaneous, separate or sequential use in the prevention, delay of progression or treatment of diseases, especially metabolic disorders and in particular type 2 diabetes and diseases and conditions associated with diabetes; to a composition, respectively, which comprises nateglinide and a pharmaceutically acceptable carrier and to a process of making such composition; the use of such combination or composition for the preparation of a medicament for the prevention, delay of progression or treatment of metabolic disorders; a method of prevention, delay of progression or treatment of diseases in warm-blooded animals; the use of such combination or composition for the cosmetic treatment of a mammal in order to effect a cosmetically beneficial loss of body weight; and to a method of improving the bodily appearance of a warm-blooded animal.