Miklos E Gellai

US Patent:

6750026, Jun 15, 2004

Filed:

Dec 15, 2000

Appl. No.:

09/737379

Inventors:

Derk J. Bergsma - Berwyn PA
David P. Brooks - West Chester PA
Miklos Gellai - Devon PA
Shelagh Wilson - Beckets Bramfield, GB
Masashi Yanagisawa - Dallas TX

Assignee:

SmithKline Beecham Corporation - Philadelphia PA
Board of Regents The University of Texas System - Dallas TX

International Classification:

G01N 3353

US Classification:

435 71, 435 4, 4352523, 435325, 530300, 530324, 530399

Abstract:

Polypeptides of HFGAN72 receptor ligands and polynucleotides encoding the polypeptides are provided. Methods of using these polypeptides to diagnose diseases relating to the under- or over-expression of HFGAN72 receptor ligands are also provided. In addition, methods of identifying agonists or antagonists of the interaction of HFGAN72 receptor ligands with the HFGAN72 receptor are provided. Methods of treatment by administering the identified agonists or antagonists to patients in need thereof are further disclosed.

US Patent:

63098547, Oct 30, 2001

Filed:

Sep 26, 1997

Appl. No.:

8/939093

Inventors:

Derk J. Bergsma - Berwyn PA
David P. Brooks - West Chester PA
Miklos Gellai - Devon PA
Shelagh Wilson - Hertford, GB
Masashi Yanagisawa - Dallas TX

Assignee:

Smithkline Beecham Corporation - Philadelphia PA
Board of Regents The University of Texas System - Austin TX

International Classification:

C07H 2104
C12P 2106
C12N 1500

US Classification:

435 691

Abstract:

Polypeptides of HFGAN72 receptor ligands and polynucleotides encoding the polypeptides are provided. Methods of using these polypeptides to diagnose diseases relating to the under- or over-expression of HFGAN72 receptor ligands are also provided. In addition, methods of identifying agonists or antagonists of the interaction of HFGAN72 receptor ligands with the HFGAN72 receptor are provided. Methods of treatment by administering the identified agonists or antagonists to patients in need thereof are further disclosed.