Min Tang

US Patent:

20040111253, Jun 10, 2004

Filed:

Dec 10, 2002

Appl. No.:

10/315537

Inventors:

Xiaoqiang Luo - Ardsley NY, US
Salim Roukos - Scarsdale NY, US
Min Tang - Cambridge MA, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F017/28

US Classification:

704/004000

Abstract:

A method, computer program product, and data processing system for training a statistical parser by utilizing active learning techniques to reduce the size of the corpus of human-annotated training samples (e.g., sentences) needed is disclosed. According to a preferred embodiment of the present invention, the statistical parser under training is used to compare the grammatical structure of the samples according to the parser's current level of training. The samples are then divided into clusters, with each cluster representing samples having a similar structure as ascertained by the statistical parser. Uncertainty metrics are applied to the clustered samples to select samples from each cluster that reflect uncertainty in the statistical parser's grammatical model. These selected samples may then be annotated by a human trainer for training the statistical parser.

US Patent:

20070110962, May 17, 2007

Filed:

Sep 23, 2004

Appl. No.:

10/572987

Inventors:

Joe Tien - Brookline MA, US
Min Tang - Allston MA, US
Andrew Golden - Allston MA, US

International Classification:

B32B 3/00

US Classification:

428156000, 428172000

Abstract:

The present invention provides three-dimensional hydrogel structures patterned by a treated micropattern mold. The treated mold is capable of transferring the inverse of its micropattern to a hydrogel by contact during formation or polymerization of the structure from a precursor. The treated micropattern mold surface allows the mold to be separated from the hydrogel without collapsing the structure or irreparably damaging its micropattern. The transferred micropattern may yield individual features and/or interconnected channels in the hydrogel. The invention also provides a hydrogel network fabricated by interfacing at least two hydrogels in which one or more of the hydrogels may be a micropatterned structure. Micropatterned hydrogel structures can also be specifically aligned to interconnect their patterns. Structures or networks of the invention comprise hydrogels that can adhere together by chemically bonding and/or mechanically entangling.

US Patent:

20180289771, Oct 11, 2018

Filed:

Apr 2, 2018

Appl. No.:

15/943304

Inventors:

- West Newton MA, US
Nikoletta L. Kallinteris - Tustin CA, US
Min Tang - Tustin CA, US
F. Andrew Dorr - Tustin CA, US

International Classification:

A61K 38/17
G01N 33/574
A61K 47/68
A61P 35/04
C07K 14/705

Abstract:

Disclosed are surprising new methods and kits for treating patients, particularly cancer patients, using bavituximab in combination therapies with immuno-oncology (IO) agents such as checkpoint inhibitor antibodies. The methods and kits are based on the surprising finding that human patients treated with bavituximab and checkpoint inhibitor antibodies have a statistically significant prolonged survival in controlled studies.