Ming M Li

US Patent:

8518259, Aug 27, 2013

Filed:

Jan 27, 2011

Appl. No.:

13/015363

Inventors:

Patrick Cloutier - Andover MN, US
Robert Olsen - Plymouth MN, US
Stephen Roller - Minneapolis MN, US
Chris Plott - St. Paul MN, US
Al McLevish - Apple Valley MN, US
Ming Li - Roseville MN, US
Michael Laxen - Minneapolis MN, US
John Knoll - Brooklyn Park MN, US
Gregory Hake - Otsego MN, US

Assignee:

Medtronic, Inc. - Minneapolis MN

International Classification:

B01D 61/30
B01D 61/28
B01D 61/20
B01D 61/18
A61M 1/36

US Classification:

210646, 210175, 210180, 210183, 210184, 210188, 210252, 210256, 210258, 210436, 210472, 210650, 422 44, 422 45, 422 46, 422 47, 422 48, 604 401, 604 501, 604 609, 604 613, 604 614, 604 28

Abstract:

An apparatus for de-aering, oxygenating and controlling a temperature of blood in an extracorporeal blood circuit. The apparatus includes a housing, a manifold body, a heat exchanger, and an oxygenator. A blood inlet tangentially directs blood into a first chamber of the housing. The manifold body is disposed in a second chamber, and includes a core and a plurality of vanes that define channels. The heat exchanger is arranged around the manifold body, and the oxygenator around the heat exchanger. The channels are open to the heat exchanger. An established blood flow path includes rotational flow within the first chamber to separate air from the blood, generally longitudinal flow from the first chamber and along the channels, and generally radial flow through the heat exchanger and the oxygenator. With this construction, gross air removal occurs prior to the blood passing through the heat exchanger and oxygenator.

US Patent:

8545754, Oct 1, 2013

Filed:

Apr 23, 2009

Appl. No.:

12/428674

Inventors:

Walt L. Carpenter - Minneapolis MN, US
Robert W. Olsen - Plymouth MN, US
Michael J. Hobday - Lino Lakes MN, US
Alford L. McLevish - Maple Grove MN, US
Christopher J. Plott - St. Paul MN, US
Roderick E. Briscoe - Rogers MN, US
Patrick J. Cloutier - Andover MN, US
Anil Thapa - Blaine MN, US
Ming Li - Roseville MN, US
Kevin McIntosh - Brooklyn Park MN, US
Ken Merte - Southlake TX, US

Assignee:

Medtronic, Inc. - Minneapolis MN

International Classification:

A61M 1/00
A61M 1/16

US Classification:

422 46, 422 44, 422 45, 422 48, 604 401, 604 609, 604 613, 604 614

Abstract:

Disclosed is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit. The apparatus has an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus. The apparatus comprises: a core that is substantially centrally located in the apparatus and to which blood from a patient can be supplied through the inlet; a heat exchanger comprising a plurality of heat transfer elements that are arranged around the core and between which blood from the core can move radially outward; and an oxygenator comprising a plurality of gas exchange elements that are arranged around the heat exchanger and between which blood from the heat exchanger can move radially outward before exiting the apparatus through the outlet.

US Patent:

8579845, Nov 12, 2013

Filed:

Jan 27, 2011

Appl. No.:

13/015398

Inventors:

Patrick Cloutier - Andover MN, US
Robert Olsen - Plymouth MN, US
Stephen Roller - Minneapolis MN, US
Chris Plott - St. Paul MN, US
Al McLevish - Apple Valley MN, US
Ming Li - Roseville MN, US
Michael Laxen - Minneapolis MN, US
John Knoll - Brooklyn Park MN, US
Gregory Hake - Otsego MN, US

Assignee:

Medtronic, Inc. - Minneapolis MN

International Classification:

A61M 1/36
A61M 1/14

US Classification:

604 613, 604 614, 422 46

Abstract:

A capillary tube bundle sub-assembly for use in an extracorporeal heat exchanger includes a continuous capillary tubing wound about a core to define a plurality of capillary layers each including a plurality of capillary segments. The capillary segments each define opposing terminal ends adjacent opposing ends of the core. The capillary segments of each layer are circumferentially aligned relative to an axis of the core, with each successive layer being radially outward of an immediately preceding layer. The capillary segments are non-parallel with the axis, spiraling partially about the axis in extension between the opposing terminal ends. Each capillary segment forms less than one complete revolution (i. e. , winds less than 360). The segments within each layer are substantially parallel with one another; however, an orientation of the segments differs from layer-to-layer such as by pitch or angle.

US Patent:

20020150842, Oct 17, 2002

Filed:

Apr 11, 2001

Appl. No.:

09/829974

Inventors:

Ming Li - Thousand Oaks CA, US

Assignee:

Solus Micro Technologies, Inc.

International Classification:

G03F007/00

US Classification:

430/323000, 430/327000

Abstract:

Elastomer thin films can be lithographically patterned by using an UV curable polydimethylsiloxane, rather than replica molding of thermal cure elastomers. The fabrication method of such patterned elastomers consists of elastomer formulation, substrate modification, spinning elastomer, pattern development, and possible a backside etch of the substrate.

US Patent:

20100269342, Oct 28, 2010

Filed:

Apr 23, 2009

Appl. No.:

12/428706

Inventors:

Walt L. Carpenter - Minneapolis MN, US
Robert W. Olsen - Plymouth MN, US
Michael J. Hobday - Lino Lakes MN, US
Alford L. McLevish - Maple Grove MN, US
Christopher J. Plott - St. Paul MN, US
Roderick E. Briscoe - Rogers MN, US
Patrick J. Cloutier - Andover MN, US
Anil Thapa - Blaine MN, US
Ming Li - Roseville MN, US

International Classification:

B21D 53/02

US Classification:

2989003

Abstract:

Described is a method of making an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit, the steps comprising: providing a core through which blood can be supplied to the apparatus from a patient; providing a heat exchanger about the core such that blood from the core can move radially outward through the heat exchanger; providing an oxygenator about the heat exchanger such that blood from the heat exchanger can move radially outward through the oxygenator; and placing the core, heat exchanger and oxygenator in a housing that includes an inlet in communication with the core and an outlet that is located radially outward from the inlet in order to define a flowpath for blood through the apparatus.

US Patent:

20100272606, Oct 28, 2010

Filed:

Apr 23, 2009

Appl. No.:

12/428697

Inventors:

Walt L. Carpenter - Minneapolis MN, US
Robert W. Olsen - Plymouth MN, US
Michael J. Hobday - Lino Lakes MN, US
Alford L. McLevish - Maple Grove MN, US
Christopher J. Plott - St. Paul MN, US
Roderick E. Briscoe - Rogers MN, US
Partick J. Cloutier - Andover MN, US
Anil Thapa - Blaine MN, US
Ming Li - Roseville MN, US

International Classification:

A61M 1/36

US Classification:

422 46

Abstract:

Described is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit comprising: an inlet mandrel that is configured such that the blood moves radially outward from the inlet mandrel through the openings in a radial direction; a heat exchanger arranged around the inlet mandrel, wherein blood can move radially outward with the transfer of heat to or from the blood; an oxygenator arranged around the heat exchanger, wherein blood can move from the heat exchanger radially outward with the transfer of oxygen into the blood; and a housing that houses the inlet mandrel, the heat exchanger and the oxygenator, and that comprises a blood inlet in communication with the inlet mandrel in order to allow blood to enter the apparatus from the patient, and a blood outlet in communication with the oxygenator in order for blood to exit the apparatus, wherein the blood outlet is located in the housing radially outward from the inlet.

US Patent:

20100272607, Oct 28, 2010

Filed:

Apr 23, 2009

Appl. No.:

12/428716

Inventors:

Walt L. Carpenter - Minneapolis MN, US
Robert W. Olsen - Plymouth MN, US
Michael J. Hobday - Lino Lakes MN, US
Alford L. McLevish - Maple Grove MN, US
Christopher J. Plott - St. Paul MN, US
Roderick E. Briscoe - Rogers MN, US
Patrick J. Cloutier - Andover MN, US
Anil Thapa - Blaine MN, US
Ming Li - Roseville MN, US
Kevin McIntosh - Brooklyn Park MN, US
Ken Merte - South Lake TX, US

International Classification:

A61M 1/36

US Classification:

422 46

Abstract:

Described is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit, the apparatus having an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus, the apparatus comprising: a core in communication with the inlet such that blood from a patient can be supplied to the core, the core comprising a first element and a second element that interfit to define openings, wherein the elements and the openings together enhance flow of blood from the patient radially outward from the core; a heat exchanger that is arranged about the core and through which blood from the core can move radially outward; and an oxygenator that is arranged about the heat exchanger and through which blood from the heat exchanger can move radially outward before exiting the apparatus through the outlet.

US Patent:

20120265481, Oct 18, 2012

Filed:

Apr 13, 2011

Appl. No.:

13/085900

Inventors:

ROBERT E. STEWART - Woodland Hills CA, US
Daryl Sakaida - Simi Valley CA, US
Michael D. Bulatowicz - Canoga Park CA, US
Ming Li - Camarillo CA, US
John Thomson Douglass - Woodland Hills CA, US

International Classification:

G01P 15/00

US Classification:

702141

Abstract:

An accelerometer system can include a sensor element comprising first and second proofmasses, the first proofmass accelerating in a first direction and the second proofmass accelerating in a second direction opposite the first direction in response to an external acceleration. A force rebalance controller applies control signals to at least one control element to provide a first force to accelerate the first proofmass toward a first null position and to at least one control element to provide a second force to accelerate the second proofmass toward a second null position. The force rebalance controller can also generate opposite polarity first and second output signals associated with respective displacements of the first and second proofmasses relative to the respective first and second null positions. An acceleration component calculates the external acceleration based on the first and second output signals.