Ming Q Tan

US Patent:

20030138973, Jul 24, 2003

Filed:

Dec 23, 2002

Appl. No.:

10/328925

Inventors:

Peter Wagner - Belmont CA, US
Dana Ault-Riche - Hayward CA, US
Steffen Nock - Redwood City CA, US
Christian Itin - Menlo Park CA, US
Ming Tan - Danville CA, US

International Classification:

G01N033/543

US Classification:

436/518000

Abstract:

Methods and devices for the parallel, in vitro screening of biomolecular activity using miniaturized microfabricated devices are provided. The biomolecules immobilized on the surface of the devices of the present invention include proteins, polypeptides, polynucleotides, polysaccharides, phospolipids, and related unnatural polymers of biological relevance. These devices are useful drug development, functional proteomics and clinical diagnostics and are preferably used for the parallel screening of families of related proteins.

US Patent:

20090042744, Feb 12, 2009

Filed:

Jul 10, 2008

Appl. No.:

12/171217

Inventors:

Peter Wagner - Redwood City CA, US
Dana Ault-Riche - Los Gatos CA, US
Steffen Nock - Redwood City CA, US
Christian Itin - Menlo Park CA, US
Ming Tan - Danville CA, US

Assignee:

Zyomyx, Inc. - Hayward CA

International Classification:

C40B 60/12

US Classification:

506 39

Abstract:

Methods and devices for the parallel, in vitro screening of biomolecular activity using miniaturized microfabricated devices are provided. The biomolecules immobilized on the surface of the devices of the present invention include proteins, polypeptides, polynucleotides, polysaccharides, phospholipids, and related unnatural polymers of biological relevance. These devices are useful drug development, functional proteomics and clinical diagnostics and are preferably used for the parallel screening of families of related proteins.

US Patent:

20140025841, Jan 23, 2014

Filed:

Jul 19, 2012

Appl. No.:

13/552696

Inventors:

Dan Li - Sunnyvale CA, US
Dipak Punnoran Koroth - Fremont CA, US
Ming Tan - San Jose CA, US
Martin Ostrowski - Sunnyvale CA, US

Assignee:

Cisco Technology, Inc. - San Jose CA

International Classification:

G06F 15/16

US Classification:

709232

Abstract:

In one embodiment, redundancy elimination for web caching may be provided. Upon receiving a request for a content object, a determination of whether the content object is cached may be made. In response to determining that the content object is not cached, the requested content object may be retrieved and, if the content object is associated with an aggregate popularity exceeding a caching threshold, the content object may be cached before providing the requested content object.

US Patent:

20140044127, Feb 13, 2014

Filed:

Aug 10, 2012

Appl. No.:

13/571786

Inventors:

Dan Li - Sunnyvale CA, US
Dipak Punnoran Koroth - Fremont CA, US
Ming Tan - San Jose CA, US
Martin Ostrowski - Sunnyvale CA, US

Assignee:

Cisco Technology, Inc. - San Jose CA

International Classification:

H04L 12/56

US Classification:

370389

Abstract:

In some embodiments, a request for a content object may be received as a data packet. Upon determining that the content object is not cached, an element of the data packet may be modified and the modified data packet may be forwarded toward a content provider of the content object.

US Patent:

20200316593, Oct 8, 2020

Filed:

Dec 5, 2019

Appl. No.:

16/705047

Inventors:

- Menlo Park CA, US
Ming X. Tan - San Bruno CA, US
Arturo M. Escajeda - Oakland CA, US

International Classification:

B01L 3/00
B01L 9/00
G01N 21/64

Abstract:

Lateral loading methods of use in high-throughput methods for screening large populations of variant proteins are provided. The methods utilize a flow cell encompassing large-scale arrays of microcapillaries, where each microcapillary comprises a solution containing a variant protein, an immobilized target molecule, and a reporter element. Immobilized target molecules may include any molecule of interest, including proteins, nucleic acids, carbohydrates, and other biomolecules.

US Patent:

20180011090, Jan 11, 2018

Filed:

Sep 13, 2017

Appl. No.:

15/703928

Inventors:

- Franklin Lakes NJ, US
Jeffrey Sugarman - Los Altos CA, US
Wei Huang - Cupertino CA, US
Edward Michael Goldberg - Los Gatos CA, US
Ming Tan - Danville CA, US

International Classification:

G01N 33/558
B01F 13/00
B01F 5/06
B01L 3/00

Abstract:

The present disclosure provides methods and systems for assaying a sample. A microfluidic device to perform an assay of a sample (e.g., biological sample) is described having a sample application site, a porous component and a flow channel. The porous component provides for uniform dissolution of a reagent and mixing of the sample and reagent without filtering the sample.

US Patent:

20160033412, Feb 4, 2016

Filed:

Jul 29, 2015

Appl. No.:

14/813015

Inventors:

Ming TAN - Danville CA, US
Leyla SABET - Los Angeles CA, US
Ashutosh SHASTRY - Santa Clara CA, US
Christopher E. TODD - Campbell CA, US
Reuven DUER - Thousand Oaks CA, US

International Classification:

G01N 21/64
G01N 21/77

Abstract:

Optical readers and alignment tools for detecting the level of an analyte. Described herein are small, disposable partially-encapsulated sensing chips for detecting an analyte level from a fluid sample (e.g., a blood sample) having an edge of the integrated sensing chip exposed to directly expose a plurality of excitation and a collection waveguides, as well as optical readers and methods of operating them. A fluid sample maybe applied to a sensing surface of the sensing chip in the housing so that an analyte level can be optically detected. Also described are methods of sensing an analyte using these devices and systems including an optical detector.

US Patent:

20150125882, May 7, 2015

Filed:

Nov 5, 2014

Appl. No.:

14/533949

Inventors:

- Franklin Lakes NJ, US
Jeffrey Sugarman - Los Altos CA, US
Wei Huang - Cupertino CA, US
Edward Michael Goldberg - Los Gatos CA, US
Ming Tan - Danville CA, US

International Classification:

G01N 33/558
B01L 3/00
G01N 33/569

US Classification:

435 724, 422502, 422 69, 436501, 4352872, 435 71

Abstract:

The present disclosure provides methods and systems for assaying a sample. A microfluidic device to perform an assay of a sample (e.g., biological sample) is described having a sample application site, a porous component and a flow channel. The porous component provides for uniform dissolution of a reagent and mixing of the sample and reagent without filtering the sample.