Ming Dong Zhang

US Patent:

20080139635, Jun 12, 2008

Filed:

Dec 5, 2007

Appl. No.:

11/950456

Inventors:

Billy R. Martin - Richmond VA, US
Mohamad Imad Damaj - Richmond VA, US
Martin W. Adler - Philadelphia PA, US
Ronald F. Tuma - Philadelphia PA, US
Ming Zhang - Philadelphia PA, US
Anu Mahadevan - Woburn MA, US
Raj K Razdan - Woburn MA, US

International Classification:

A61K 31/4164
A61P 25/28
A61K 31/045

US Classification:

514397, 514734

Abstract:

A method is provided for treating a patient in need of therapy for central nervous system inflammation comprising administering to that patient a therapeutically effective amount of a cannabinoid agonist having efficacy at the CBreceptor but having substantially no efficacy at the CBreceptor at that amount.

US Patent:

20110223617, Sep 15, 2011

Filed:

Jul 9, 2009

Appl. No.:

13/003332

Inventors:

Ming Zhang - Brooklyn NY, US

International Classification:

G01N 33/566

US Classification:

435 79, 436501, 435 71

Abstract:

The present invention relates to the quantitative measurement of auto-reactive antibodies in a patient sample. In particular, the present invention is directed to, inter alia, a method for predicting the degree of cardiovascular injury in a patient following an ischemic event, said method comprising: immobilizing anti-NMHC II antibody on a solid support; adding a lysate of cardiac tissue to the solid support so that antigens in the lysate are captured by the immobilized antibody; adding a biological sample from the patient to said solid support, and incubating said sample for a time sufficient for IgM autoantibodies in the biological sample to bind to antigens in the cardiac tissue lysate; contacting said solid support with an anti-IgM antibody; removing unbound labeled antibodies; and determining the level of anti NMHC II autoantibodies in the biological sample by measuring the amount of labeled anti-IgM antibody bound to the solid support, wherein elevated levels of anti-NMHC II autoantibodies compared to normal individuals at time of patient admission indicates an increased risk of injury. Such methods are useful, inter alia, in the prognosis and monitoring of cardiovascular diseases.

US Patent:

20180043512, Feb 15, 2018

Filed:

Oct 21, 2017

Appl. No.:

15/789986

Inventors:

Ming Liang Zhang - Brooklyn NY, US
Ming Zhu Zhang - Brooklyn NY, US

International Classification:

B25B 13/46
B25B 17/00

Abstract:

A ratchet wrench includes a first and a second drive members ′ rotatably mounted in a first and a second heads ′ extended from a first and a second ends of a handle . The first drive member includes a square inner periphery adapted to slidably retain a drive shaft including a ″ drive fitting and a ⅜″ drive fitting , and the second drive member ′ includes a ″ drive hexagonal bit holder and ″ drive fitting , for providing combined functions of ordinary ratchet wrenches for turning fasteners. A first and a second ratcheting mechanisms are mounted in the first and the second ends of the handle for turning the first and the second drive members ′, by the handle

US Patent:

20160332284, Nov 17, 2016

Filed:

May 2, 2016

Appl. No.:

15/144344

Inventors:

Ming Liang Zhang - Brooklyn NY, US
Ming Zhu Zhang - Brooklyn NY, US

International Classification:

B25B 13/46
B25B 13/48

Abstract:

A ratchet wrench includes a first and a second drive members rotatably mounted in a first and a second heads extended from a first and a second ends of a handle The first drive member includes a square inner periphery adapted to slidably retain a drive shaft including a ″ drive fitting and a 3/8″ drive fitting and the second drive member ′ includes a ″ drive hexagonal bit holder and ″ drive fitting for providing combined functions of ordinary ratchet wrenches for turning fasteners. A first and a second ratcheting mechanisms are mounted in the first and the second ends of the handle for turning the first and the second drive members by the handle