Minjie Hu

US Patent:

20190000899, Jan 3, 2019

Filed:

Mar 28, 2017

Appl. No.:

15/744295

Inventors:

Minjie HU - Foster City CA, US
Yu LI - Johns Creek GA, US
Xiaoling LIU - Pearland TX, US
Rebecca HU - Foster City CA, US

International Classification:

A61K 35/768
A61P 35/00
A61K 39/39
A61K 35/745

Abstract:

Therapeutic methods for administering gut microbiota and oncolytic viruses to a subject are provided. The gut microbiota serve to pre-condition, the subject's immune system to antitumor responses and augments anticancer activity of the oncolytic vims. Combinations of the gut. microbiota and viruses and uses thereof for treating and preventing cancer are provided. The present disclosure also provides methods for building elite responder selection platforms through hierarchical clustering analysis of genomic profiles for human gut microbiome.